1PMS: SOS 1

Pleckstrin homology domain of son of sevenless 1 (SOS1) with glycine-serine added to the N-terminus, NMR, 20 structures. Determined by solution NMR. Released 15 May 1997.

Method
Solution NMR
Organism
Mus musculus
Chains
1
Atoms
1,085
Mol. weight
15.57 kDa
Released
15 May 1997

Explore 1PMS in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1PMS contains 2 α-helices and 11 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 2 helices, 11 β-strands

ElementResiduesLengthSheet
α-helix436-4449
β-strand463-46751
β-strand46812
β-strand476-48051
β-strand484-48851
β-strand507-51261
β-strand517-51933
β-strand52414
β-strand52714
β-strand531-53443
β-strand540-54343
β-strand54412
α-helix549-56214

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
SOS 1Aprotein136Mus musculusQ62245 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>1PMS_1 SOS 1 (chains A)
GSKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCK
SNHGQPRLPGASSAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAE
EKNNWMAALISLQYRS

Primary citation

The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1). Koshiba, S., Kigawa, T., Kim, J.H. et al. J Mol Biol (1997) 269:579-591. DOI 10.1006/jmbi.1997.1041 · PubMed

Other PDB entries of the same protein (UniProt Q62245 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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