1W0S: Properdin

Solution structure of trimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation. Determined by solution scattering. Released 6 Jul 2005.

Method

Solution scattering

Organism

HOMO SAPIENS

Chains

3

Atoms

1,326

Mol. weight

145.66 kDa

Released

6 Jul 2005

Explore 1W0S in 3D Show helices and sheets RCSB PDB PDBe

Molecules and chains

>1W0S_1 PROPERDIN (chains A, B, C)
DPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWA
PCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEP
CSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSA
SCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVS
PCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPC
IRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWST
WGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKL
VVEEKRPCLHVPACKDPEEEEL

Primary citation

The Dimeric and Trimeric Solution Structures of the Multidomain Complement Protein Properdin by X-Ray Scattering, Analytical Ultracentrifugation and Constrained Modelling. Sun, Z., Reid, K.B.M., Perkins, S.J. J Mol Biol (2004) 343:1327. DOI 10.1016/J.JMB.2004.09.001 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P27918 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 8Q6R 1.9 Å, Structure of complement FP in complex with the TPP-3077 VHH
• 6S08 2.03 Å, Crystal Structure of Properdin (TSR domains N1 & 456)
• 6S0B 2.31 Å, Crystal Structure of Properdin in complex with the CTC domain of C3/C3b
• 6S0A 2.52 Å, Crystal Structure of Properdin (TSR domains N12 & 456)
• 9U62 2.7 Å, AP pathways C3 convertase C3bBbP and C3 complex
• 6RUS 2.8 Å, Structure of a functional properdin monomer
• 7B26 3.4 Å, CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
• 6SEJ 3.5 Å, Structure of a functional monomeric properdin lacking TSR3
• 6RV6 3.51 Å, Structure of properdin lacking TSR3 based on anomalous data
• 7NOZ 3.9 Å, Structure of the nanobody stablized properdin bound alternative pathway proconvertase…
• 6RUR 6.0 Å, Structure of the SCIN stabilized C3bBb convertase bound to properdin
• 6RUV 6.15 Å, Structure of the SCIN stabilized C3bBb convertase bound to Properdin and a the…

Browse structure collections

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