1Y1V: Refined RNA Polymerase II-TFIIS complex

Refined RNA Polymerase II-TFIIS complex. Determined by X-ray diffraction at 3.8 Å resolution. Released 28 Dec 2004.

Method: X-ray diffraction
Resolution: 3.8 Å
Organism: Saccharomyces cerevisiae
Chains: 13
Atoms: 31,803
Mol. weight: 535.04 kDa
Ligands: MG, ZN
Released: 28 Dec 2004

Explore 1Y1V in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1Y1V contains 150 α-helices and 228 β-strands across 13 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 65 helices, 73 β-strands

Element	Residues	Length	Sheet
β-strand	11-12	2	1
β-strand	16-21	6	2
α-helix	24-30	7
β-strand	82	1	3
β-strand	85-90	6	4
α-helix	96-104	9
β-strand	107	1	5
β-strand	112	1	5
α-helix	120-126	7
α-helix	135-138	4
β-strand	147	1	6
β-strand	151-153	3	7
β-strand	161-163	3	7
β-strand	170	1	6
α-helix	171-172	2
β-strand	173-177	5	8
β-strand	180-184	5	8
β-strand	200-202	3	8
α-helix	204-213	10
α-helix	216-221	6
β-strand	225	1	9
β-strand	229	1	9
α-helix	231-233	3
β-strand	236-238	3	4
β-strand	241	1	3
α-helix	244-246	3
β-strand	251	1	10
β-strand	257	1	10
α-helix	261-277	17
α-helix	286-288	3
α-helix	293-302	10
β-strand	316	1	11
β-strand	320	1	11
α-helix	325-329	5
α-helix	335-340	6
β-strand	343-345	3	12
β-strand	348-355	8	13
β-strand	363-367	5	13
α-helix	368-371	4
β-strand	375-379	5	14
α-helix	385-394	10
β-strand	402	1	14
β-strand	405-407	3	14
β-strand	411-413	3	14
β-strand	428	1	15
β-strand	430	1	15
β-strand	431-435	5	14
β-strand	441-445	5	13
α-helix	452-454	3
β-strand	455-463	9	13
β-strand	468-470	3	13
α-helix	472-474	3
β-strand	486-490	5	13
α-helix	495-502	8
β-strand	506	1	13
α-helix	507-510	4
β-strand	512-513	2	16
α-helix	514-516	3
β-strand	518-519	2	16
α-helix	525-535	11
β-strand	540-542	3	17
α-helix	543-552	10
α-helix	560-562	3
β-strand	565	1	18
β-strand	571-573	3	17
α-helix	574-578	5
α-helix	579-581	3
β-strand	587-589	3	19
β-strand	606-608	3	19
β-strand	611-614	4	19
α-helix	619-622	4
α-helix	629-636	8
α-helix	639-660	22
β-strand	662-663	2	20
α-helix	666-668	3
α-helix	673-695	23
α-helix	710-736	27
α-helix	742-749	8
α-helix	755-762	8
β-strand	766-767	2	21
α-helix	794-797	4
β-strand	799-800	2	21
α-helix	810-820	11
α-helix	823-826	4
α-helix	830-844	15
β-strand	849	1	22
β-strand	857	1	22
α-helix	868-870	3
β-strand	873	1	23
β-strand	879-882	4	24
α-helix	890-897	8
α-helix	928-944	17
β-strand	953-956	4	24
α-helix	960-969	10
α-helix	983-994	12
α-helix	1005-1025	21
α-helix	1028-1033	6
α-helix	1039-1056	18
β-strand	1057	1	23
α-helix	1058-1059	2
α-helix	1064-1078	15
α-helix	1098-1106	9
β-strand	1117-1119	3	25
β-strand	1120	1	26
α-helix	1130-1138	9
β-strand	1139	1	27
β-strand	1142	1	28
α-helix	1143-1146	4
β-strand	1147	1	29
β-strand	1151-1154	4	30
α-helix	1167-1175	9
β-strand	1191-1194	4	30
β-strand	1197	1	29
α-helix	1200-1202	3
α-helix	1209-1220	12
β-strand	1225-1226	2	31
β-strand	1240-1241	2	31
α-helix	1259-1265	7
β-strand	1272	1	28
β-strand	1276	1	27
β-strand	1283-1287	5	25
β-strand	1290-1292	3	32
β-strand	1298-1300	3	32
β-strand	1303-1307	5	25
α-helix	1313-1316	4
β-strand	1322	1	26
β-strand	1328	1	25
α-helix	1332-1337	6
α-helix	1341-1357	17
α-helix	1366-1376	11
α-helix	1389-1391	3
α-helix	1396-1400	5
α-helix	1405-1413	9
β-strand	1419	1	2
α-helix	1424-1428	5
α-helix	1437-1439	3
β-strand	1442-1445	4	33
α-helix	1447-1451	5

Chain B: 41 helices, 71 β-strands

Element	Residues	Length	Sheet
α-helix	27-40	14
α-helix	45-56	12
α-helix	58-63	6
β-strand	91-97	7	34
α-helix	114-119	6
β-strand	127-133	7	34
β-strand	166-169	4	34
α-helix	172-173	2
α-helix	186-190	5
β-strand	210-211	2	35
β-strand	214-218	5	36
β-strand	223-227	5	37
β-strand	234	1	38
β-strand	236-242	7	37
β-strand	252-256	5	37
β-strand	259	1	38
β-strand	270-272	3	37
β-strand	280-281	2	37
α-helix	282-288	7
α-helix	298-301	4
α-helix	308-321	14
α-helix	327-332	6
α-helix	348-354	7
α-helix	355-359	5
α-helix	371-389	19
α-helix	401-403	3
β-strand	404-407	4	36
α-helix	409-432	24
α-helix	451-462	12
β-strand	481-482	2	35
α-helix	489-495	7
β-strand	497-499	3	36
β-strand	522	1	39
β-strand	537-538	2	36
β-strand	539	1	39
β-strand	544-545	2	40
α-helix	552-558	7
β-strand	564	1	41
α-helix	566-568	3
β-strand	580-582	3	42
β-strand	585-586	2	42
β-strand	589	1	41
α-helix	593-604	12
β-strand	614-618	5	42
α-helix	619-621	3
β-strand	623-627	5	42
β-strand	633-634	2	40
β-strand	637-639	3	43
α-helix	655-666	12
α-helix	681-686	6
β-strand	690-691	2	43
β-strand	694	1	40
α-helix	696-699	4
β-strand	703-704	2	43
β-strand	740-741	2	43
α-helix	745-748	4
α-helix	751-754	4
β-strand	762	1	44
α-helix	764-773	10
β-strand	777	1	45
β-strand	779	1	46
α-helix	785-787	3
β-strand	794-796	3	46
β-strand	800	1	47
β-strand	804-805	2	48
α-helix	807-811	5
β-strand	820-827	8	47
β-strand	828-829	2	20
β-strand	838-841	4	47
α-helix	843-847	5
β-strand	853-856	4	46
β-strand	859-862	4	49
β-strand	865	1	50
β-strand	871	1	50
β-strand	873	1	51
α-helix	890-892	3
β-strand	898	1	52
β-strand	910	1	53
β-strand	912	1	52
β-strand	915-916	2	51
β-strand	935-936	2	51
β-strand	940	1	53
β-strand	948-951	4	46
β-strand	954-957	4	49
β-strand	961-966	6	49
β-strand	967-972	6	46
β-strand	979-981	3	47
β-strand	988-992	5	47
β-strand	1001	1	54
β-strand	1010-1012	3	47
α-helix	1014-1016	3
α-helix	1018-1020	3
β-strand	1022	1	44
α-helix	1023-1038	16
β-strand	1042-1043	2	48
α-helix	1052-1060	9
β-strand	1069-1070	2	47
β-strand	1073	1	54
α-helix	1079	1
β-strand	1080	1	54
α-helix	1081	1
β-strand	1085-1093	9	47
β-strand	1095	1	45
α-helix	1099-1101	3
β-strand	1104-1106	3	13
β-strand	1128-1130	3	12
α-helix	1132-1141	10
α-helix	1144-1151	8
β-strand	1159-1163	5	1
β-strand	1191-1195	5	1
α-helix	1198-1209	12
β-strand	1212-1217	6	2

Chain C: 8 helices, 13 β-strands

Element	Residues	Length	Sheet
β-strand	8	1	55
β-strand	13	1	55
β-strand	17-22	6	55
α-helix	27-39	13
β-strand	45-54	10	56
α-helix	60-69	10
β-strand	72	1	57
α-helix	75-77	3
β-strand	99-103	5	56
β-strand	113-114	2	58
α-helix	115-117	3
β-strand	119-120	2	56
β-strand	132	1	57
β-strand	143-145	3	58
β-strand	153-160	8	56
α-helix	164-166	3
β-strand	176-177	2	55
α-helix	197-200	4
α-helix	205-209	5
β-strand	228-233	6	55
α-helix	240-263	24

Chain D: 8 helices, 3 β-strands

Element	Residues	Length	Sheet
α-helix	31-33	3
β-strand	37-38	2	59
β-strand	44-45	2	59
β-strand	49-50	2	60
α-helix	54-71	18
α-helix	120-133	14
α-helix	139-151	13
α-helix	159-167	9
α-helix	174-179	6
α-helix	188-194	7
α-helix	204-217	14

Chain E: 13 helices, 17 β-strands

Element	Residues	Length	Sheet
α-helix	3-5	3
α-helix	6-25	20
β-strand	28	1	61
α-helix	32-35	4
α-helix	39-46	8
β-strand	47	1	62
β-strand	53	1	62
α-helix	55-57	3
β-strand	60-62	3	63
β-strand	64	1	61
α-helix	67-71	5
β-strand	78-82	5	63
β-strand	87	1	64
α-helix	92-103	12
β-strand	107-112	6	63
β-strand	115	1	64
α-helix	124-126	3
β-strand	131-136	6	63
α-helix	137-140	4
α-helix	144-146	3
β-strand	155	1	65
α-helix	160-166	7
α-helix	172-174	3
β-strand	177-178	2	66
α-helix	183-187	5
β-strand	196	1	65
β-strand	200-201	2	67
β-strand	207-208	2	67
β-strand	212	1	65
β-strand	213-214	2	66

Chain F: 2 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	84	1	68
α-helix	87-102	16
α-helix	117-126	10
β-strand	132-137	6	33
β-strand	143-147	5	33
β-strand	152	1	68

Chain G: 2 helices, 19 β-strands

Element	Residues	Length	Sheet
β-strand	2-7	6	60
β-strand	10-13	4	33
α-helix	22-33	12
β-strand	37-39	3	60
β-strand	43-48	6	60
β-strand	55	1	69
β-strand	59-61	3	33
β-strand	68-71	4	33
β-strand	73	1	69
β-strand	74-79	6	60
β-strand	86-95	10	70
β-strand	98-103	6	70
β-strand	106-111	6	70
α-helix	112-114	3
β-strand	119-122	4	71
β-strand	129-132	4	71
β-strand	136-137	2	71
β-strand	142-146	5	70
β-strand	149-153	5	70
β-strand	156-160	5	70
β-strand	169-170	2	70

Chain H: 1 helix, 13 β-strands

Element	Residues	Length	Sheet
β-strand	7-16	10	72
β-strand	23-30	8	72
β-strand	37-43	7	72
β-strand	54-58	5	72
α-helix	84-86	3
β-strand	95	1	73
β-strand	97	1	18
β-strand	98	1	74
β-strand	100-106	7	72
β-strand	112-118	7	72
β-strand	121-127	7	72
β-strand	141	1	74
β-strand	143	1	72
β-strand	144	1	73

5 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase II largest subunit	A	protein	1733	Saccharomyces cerevisiae	P04050 (AlphaFold model)
DNA-directed RNA polymerase II 140 kDa polypeptide	B	protein	1224	Saccharomyces cerevisiae	P08518 (AlphaFold model)
DNA-directed RNA polymerase II 45 kDa polypeptide	C	protein	318	Saccharomyces cerevisiae	P16370 (AlphaFold model)
DNA-directed RNA polymerase II 32 kDa polypeptide	D	protein	221	Saccharomyces cerevisiae	P20433 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide	E	protein	215	Saccharomyces cerevisiae	P20434
DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide	F	protein	155	Saccharomyces cerevisiae	P20435
DNA-directed RNA polymerase II 19 kDa polypeptide	G	protein	171	Saccharomyces cerevisiae	P34087
DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide	H	protein	146	Saccharomyces cerevisiae	P20436
DNA-directed RNA polymerase II subunit 9	I	protein	122	Saccharomyces cerevisiae	P27999
DNA-directed RNA polymerases I/II/III subunit 10	J	protein	70	Saccharomyces cerevisiae	P22139
DNA-directed RNA polymerase II 13.6 kDa polypeptide	K	protein	120	Saccharomyces cerevisiae	P38902
DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide	L	protein	70	Saccharomyces cerevisiae	P40422

1 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>1Y1V_1 DNA-directed RNA polymerase II largest subunit (chains A)
MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGS
IDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNE
LMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLK
LVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLP
VPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHV
ATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLE
LDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKR
AGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNA
DFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTF
IELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSP
KDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHN
GFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVR
FLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFV
DRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRR
LVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVD
LLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNI
RRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCC
LLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMT
LNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEH
TTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRA
AMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHML
KKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVP
GIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGG
LTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGA
FDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGS
NDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTS
PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS
PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR

Sequence of entity 2 (B), FASTA

>1Y1V_2 DNA-directed RNA polymerase II 140 kDa polypeptide (chains B)
MSDLANSEKYYDEDPYGFEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQ
DIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLR
NLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCY
LSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEI
RSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEH
ICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEF
LPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTL
FKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVS
QVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLS
LMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETL
RTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAK
LMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEEND
LDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGV
FLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMI
MNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIA
PGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDG
LKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSR
MTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKK
LMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIA
HGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAA
KLLFQELMAMNITPRLYTDRSRDF

Sequence of entity 3 (C), FASTA

>1Y1V_3 DNA-directed RNA polymerase II 45 kDa polypeptide (chains C)
MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD
EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI
VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY
DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV
DQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPY
SNASQMGNTGSGGYDNAW

Sequence of entity 4 (D), FASTA

>1Y1V_4 DNA-directed RNA polymerase II 32 kDa polypeptide (chains D)
MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIK
EALVERRRAFKRSQKKHKKKHLKHENANDETTAVEDEDDDLDEDDVNADDDDFMHSETRE
KELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQL
GSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY

Sequence of entity 5 (E), FASTA

>1Y1V_5 DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>1Y1V_6 DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>1Y1V_7 DNA-directed RNA polymerase II 19 kDa polypeptide (chains G)
MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGR
ILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLT
FNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI

Sequence of entity 8 (H), FASTA

>1Y1V_8 DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>1Y1V_9 DNA-directed RNA polymerase II subunit 9 (chains I)
MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQ
DIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ
FS

Sequence of entity 10 (J), FASTA

>1Y1V_10 DNA-directed RNA polymerases I/II/III subunit 10 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>1Y1V_11 DNA-directed RNA polymerase II 13.6 kDa polypeptide (chains K)
MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAA
YKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF

Sequence of entity 12 (L), FASTA

>1Y1V_12 DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
MG	Magnesium ion	Mg	1
ZN	Zinc ion	Zn	9

Primary citation

Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Kettenberger, H., Armache, K.J., Cramer, P. Mol Cell (2004) 16:955-965. DOI 10.1016/j.molcel.2004.11.040 · PubMed

Other PDB entries of the same protein (UniProt P04050 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5VKO 1.8 Å, SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493
9SV6 1.96 Å, CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1
5VKL 2.2 Å, SPT6 tSH2-RPB1 1476-1500 pS1493
9W8V 2.23 Å, Structure of post-translocation state of yeast Pol II complexed with a cisplatin-induced…
9QEB 2.26 Å, CryoEM structure of transcribing RNA polymerase II elongation complex
1TWF 2.3 Å, RNA polymerase II complexed with UTP at 2.3 A resolution
9RYB 2.33 Å, CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis…
9KD8 2.46 Å, The structure of RNA polymerase II elongation complex paused at N-2 state by actinomycin…
6NPW 2.49 Å, SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide
9K7F 2.5 Å, RNA polymerase II elongation complex apo structure.
30ES 2.54 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…
30EP 2.55 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…

Browse structure collections

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