Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein. Determined by X-ray diffraction at 1.2 Å resolution. Released 9 Aug 2005.
Explore 2A26 in 3D Show helices and sheets RCSB PDB PDBe
2A26 contains 6 α-helices and 0 β-strands across 3 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 3-19 | 17 | |
| α-helix | 23-46 | 24 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 3-19 | 17 | |
| α-helix | 23-42 | 20 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Calcyclin-binding protein | A, B, C | protein | 50 | Homo sapiens | Q9HB71 (AlphaFold model) |
>2A26_1 Calcyclin-binding protein (chains A, B, C) GSHMASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQK
| ID | Name | Formula | Copies |
|---|---|---|---|
| CXS | 3-cyclohexyl-1-propylsulfonic acid | C9 H19 N O3 S | 1 |
Water and common crystallization additives (SO4) are not listed.
Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex. Santelli, E., Leone, M., Li, C. et al. J Biol Chem (2005) 280:34278-34287. DOI 10.1074/jbc.M506707200 · PubMed
Other PDB entries of the same protein (UniProt Q9HB71 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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