2BUO: HIV-1 capsid C-terminal domain

HIV-1 capsid C-terminal domain in complex with an inhibitor of particle assembly. Determined by X-ray diffraction at 1.7 Å resolution. Released 21 Jul 2005.

Method: X-ray diffraction
Resolution: 1.7 Å
Organisms: HUMAN IMMUNODEFICIENCY VIRUS 1, SYNTHETIC CONSTRUCT
Chains: 2
Atoms: 894
Mol. weight: 11.04 kDa
Released: 21 Jul 2005

Explore 2BUO in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2BUO contains 6 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 5 helices, 0 β-strands

Element	Residues	Length
α-helix	150-152	3
α-helix	161-174	14
α-helix	179-192	14
α-helix	196-205	10
α-helix	211-218	8

Chain T: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	3-10	8

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
HIV-1 capsid protein	A	protein	86	HUMAN IMMUNODEFICIENCY VIRUS 1	P03347
Inhibitor of capsid assembly	T	protein	12	SYNTHETIC CONSTRUCT

Sequence of entity 1 (A), FASTA

>2BUO_1 HIV-1 CAPSID PROTEIN (chains A)
SPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKAL
GPGATLEEMMTACQGVGGPGHKARVL

Sequence of entity 2 (T), FASTA

>2BUO_2 INHIBITOR OF CAPSID ASSEMBLY (chains T)
ITFEDLLDYYGP

Primary citation

The HIV-1 Capsid Protein C-Terminal Domain in Complex with a Virus Assembly Inhibitor. Ternois, F., Sticht, J., Duquerroy, S. et al. Nat Struct Mol Biol (2005) 12:678. DOI 10.1038/NSMB967 · PubMed

Other PDB entries of the same protein (UniProt P03347), best resolution first:

6BHR 2.91 Å, HIV-1 immature CTD-SP1 hexamer in complex with IP6
5KP9 5.7 Å, Structure of Nanoparticle Released from Enveloped Protein Nanoparticle

Browse structure collections

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