2I5Z: OspA mutant

The crystal structure of OspA mutant. Determined by X-ray diffraction at 1.2 Å resolution. Released 10 Jul 2007.

Method: X-ray diffraction
Resolution: 1.2 Å
Organism: Borrelia burgdorferi
Chains: 1
Atoms: 2,475
Mol. weight: 26.57 kDa
Released: 10 Jul 2007

Explore 2I5Z in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2I5Z contains 3 α-helices and 23 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain O: 3 helices, 23 β-strands

Element	Residues	Length	Sheet
β-strand	29-34	6	1
α-helix	35-37	3
β-strand	38-43	6	1
α-helix	51	1
β-strand	52-58	7	1
β-strand	61-67	7	1
β-strand	74-79	6	1
β-strand	85-90	6	1
β-strand	96-102	7	1
β-strand	109-116	8	1
β-strand	121-126	6	1
β-strand	132-138	7	1
β-strand	144-148	5	1
β-strand	156-161	6	1
β-strand	166-171	6	1
β-strand	175-182	8	1
β-strand	185-192	8	1
β-strand	197-203	7	1
β-strand	212-217	6	2
β-strand	222-227	6	2
β-strand	230-237	8	2
β-strand	243-247	5	2
β-strand	248	1	3
β-strand	255	1	3
β-strand	260-262	3	2
α-helix	265-272	8

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Outer surface protein A	O	protein	251	Borrelia burgdorferi	P0CL66 (AlphaFold model)

Sequence of entity 1 (O), FASTA

>2I5Z_1 Outer surface protein A (chains O)
GSHMKNSVSVDLPGSMKVLVSKSSNADGKYDLIATVDALELSGTSDKNNGSGVLEGVKAD
ASKVKLTISDDLGQTTLEVFKSDGSTLVSKKVTSKDKSSTEEKANEKGEVSEKIITRADG
TRLEYTGIKSDGSGKAKEVLKGYVLEGTLTAEKTTLVVKEGTVTLSKNISKSGEVSVELN
DTDSSAATKKTAAWNSGTSTLTITVNSKKTKDLVFTSSNTITVQQYDSNGTSLEGSAVEI
TKLDEIKNALK

Primary citation

Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet. Yan, S., Gawlak, G., Makabe, K. et al. J Mol Biol (2007) 368:230-243. DOI 10.1016/j.jmb.2007.02.003 · PubMed

Other PDB entries of the same protein (UniProt P0CL66 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2I5V 1.1 Å, Crystal structure of OspA mutant
2G8C 1.15 Å, Atomic-resolution crystal structure of Borrelia burgdorferi OspA via surface entropy…
6J48 1.2 Å, Glycine mutation on single layer beta-sheet of OspAsm1
9WVV 1.27 Å, The crystal structure of OspA mutant
2OYB 1.3 Å, The crystal structure of OspA mutant
2OL7 1.35 Å, The crystal structure of OspA mutant
6KWV 1.37 Å, A Crystal Structure of OspA mutant
2PI3 1.4 Å, The crystal structure of OspA mutant
6ICS 1.4 Å, Loop deletion mutant (deleting four residues)
6KT1 1.43 Å, Crystal structure of an OspA mutant
6KWU 1.43 Å, A Crystal Structure of OspA mutant
6J6E 1.5 Å, Borrelia burgdorferi OspA via surface entropy reduction (form5)

Browse structure collections

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