2JIK: PDZ domain of Synaptojanin-2 binding protein

Crystal structure of PDZ domain of Synaptojanin-2 binding protein. Determined by X-ray diffraction at 1.35 Å resolution. Released 10 Jul 2007.

Method: X-ray diffraction
Resolution: 1.35 Å
Organism: HOMO SAPIENS
Chains: 2
Atoms: 1,828
Mol. weight: 22.07 kDa
Released: 10 Jul 2007

Explore 2JIK in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2JIK contains 7 α-helices and 16 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 4 helices, 8 β-strands

Element	Residues	Length	Sheet
α-helix	6-8	3
β-strand	9-17	9	1
β-strand	25-29	5	1
β-strand	36	1	2
β-strand	39	1	2
β-strand	42-47	6	1
α-helix	52-56	5
α-helix	63	1
β-strand	64-68	5	1
β-strand	71-72	2	1
α-helix	78-86	9
β-strand	91-99	9	1

Chain B: 3 helices, 8 β-strands

Element	Residues	Length	Sheet
α-helix	6-8	3
β-strand	9-17	9	3
β-strand	19	1	4
β-strand	22	1	4
β-strand	25-29	5	3
β-strand	42-47	6	3
α-helix	52-56	5
β-strand	64-68	5	3
β-strand	71-72	2	3
α-helix	78-86	9
β-strand	91-99	9	3

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Synaptojanin-2 binding protein	A, B	protein	101	HOMO SAPIENS	P57105 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>2JIK_1 SYNAPTOJANIN-2 BINDING PROTEIN (chains A, B)
SMDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGD
KILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLESSI

Primary citation

Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein. Tickle, J., Phillips, C., Pike, A.C.W. et al. To be published.

Other PDB entries of the same protein (UniProt P57105 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2JIN 1.5 Å, Crystal structure of PDZ domain of Synaptojanin-2 binding protein
7P73 1.85 Å, The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1
7P74 1.9 Å, The PDZ domain of SYNJ2BP complexed with the phosphorylated PDZ-binding motif of RSK1
8AEL 2.2 Å, SYNJ2BP complex with a synthetic Vangl2 peptide (3mer).
7PC9 2.4 Å, The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1
7R2M 2.4 Å, SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).
7R2T 2.5 Å, SYNJ2BP complex with a phosphorylated Vangl2 peptide at the P-1 position.
2ENO Solution structure of the PDZ domain from human Synaptojanin 2 binding protein

Browse structure collections

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