ZO1 ZU5 domain in complex with GRINL1A peptide. Determined by solution NMR. Released 30 Mar 2011.
Explore 2KXS in 3D Show helices and sheets RCSB PDB PDBe
2KXS contains 1 α-helix and 10 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 3-9 | 7 | 1 |
| β-strand | 16-24 | 9 | 1 |
| β-strand | 29-33 | 5 | 2 |
| β-strand | 38-42 | 5 | 2 |
| β-strand | 53-60 | 8 | 1 |
| β-strand | 76 | 1 | 1 |
| β-strand | 82-84 | 3 | 1 |
| β-strand | 89-99 | 11 | 2 |
| α-helix | 104-107 | 4 | |
| β-strand | 125-132 | 8 | 2 |
| β-strand | 138-144 | 7 | 1 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Tight junction protein ZO-1,Myocardial zonula adherens protein | A | protein | 146 | Homo sapiens | P0CAP1 (AlphaFold model), Q07157 (AlphaFold model) |
>2KXS_1 Tight junction protein ZO-1,Myocardial zonula adherens protein (chains A) HSSGLEVLFQGPGSTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVC RDNSILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLV GANCVSVLIDHFGSGSGVVYGVVRRS
Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration. Huo, L., Wen, W., Wang, R. et al. EMBO J (2011) 30:665-678. DOI 10.1038/emboj.2010.353 · PubMed
MolViewer shows 2KXS directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.