2LNE: Neurotensin

Neurotensin 40 structures in water pH 5.5 298 K. NMR data & structures. Determined by solution NMR. Released 14 Nov 2012.

Method: Solution NMR
Organism: Homo sapiens
Chains: 1
Atoms: 120
Mol. weight: 1.69 kDa
Released: 14 Nov 2012

Explore 2LNE in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2LNE contains 1 α-helix and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	2-6	5

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Neurotensin	A	protein	13	Homo sapiens	P30990 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>2LNE_1 Neurotensin (chains A)
ELYENKPRRPYIL

Primary citation

Modulation of the neurotensin solution structure in the presence of ganglioside GM1 bicelle. Khatun, U.L., Goswami, S.K., Mukhopadhyay, C. Biophys Chem (2012) 168:48-59. DOI 10.1016/j.bpc.2012.06.003 · PubMed

Other PDB entries of the same protein (UniProt P30990 (AlphaFold model), which also has an AlphaFold model), best resolution first:

8VJY 1.95 Å, Structure of Human Neurolysin in complex with Neurotensin peptide
3F6K 2.0 Å, Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with neurotensin
4PO7 2.66 Å, Structure of the Sortilin:neurotensin complex at excess neurotensin concentration
5LUZ 2.7 Å, Structure of Human Neurolysin (E475Q) in complex with neurotensin peptide products
6UP7 4.2 Å, neurotensin receptor and arrestin2 complex
2LNF Neurotensin 40 structures in DMPC/CHAPS(q=0.25) bicelle pH 5.5 & 298K. NMR data &…
2LNG Neurotensin 40 structures in DMPC:CHAPS:GM1(q= 0.25) bicelle pH 5.5 & 298K. NMR data &…
2LYW Intermolecular interactions between neurotensin and the third extracellular loop of…
2OYV Neurotensin in DPC micelles
2OYW Neurotensin in TFE:H2O (80:20)

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