2LYW: Neurotensin receptor type 1
Intermolecular interactions between neurotensin and the third extracellular loop of human neurotensin 1 receptor. Determined by solution NMR. Released 12 Dec 2012.
- Method
- Solution NMR
- Organism
- Homo sapiens
- Chains
- 2
- Atoms
- 346
- Mol. weight
- 4.86 kDa
- Released
- 12 Dec 2012
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RCSB PDB
PDBe
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Neurotensin receptor type 1 | A | protein | 24 | Homo sapiens | P30989 (AlphaFold model) |
| Neurotensin | B | protein | 13 | Homo sapiens | P30990 (AlphaFold model) |
Sequence of entity 1 (A), FASTA
>2LYW_1 Neurotensin receptor type 1 (chains A)
VRRLMFSYISDEQWTPFLYDFYHY
Sequence of entity 2 (B), FASTA
>2LYW_2 Neurotensin (chains B)
QLYENKPRRPYIL
Primary citation
Intermolecular interactions between the neurotensin and the third extracellular loop of human neurotensin 1 receptor. Da Costa, G., Bondon, A., Coutant, J. et al. J Biomol Struct Dyn (2013) 31:1381-1392. DOI 10.1080/07391102.2012.736776 · PubMed
Other PDB entries of the same protein (UniProt P30989 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9P7Z 2.1 Å, NTSR1-Gi-NTS(8-13) Complex in the Canonical, AHD Open State (C-Open-Apo)
- 9YCX 2.1 Å, Neurotensin Receptor 1 (NTSR1) bound to Octotensin in complex with Gi3 in the…
- 9YCY 2.2 Å, Neurotensin Receptor 1 (NTSR1) bound to Octotensin in complex with Gi3 in the Canonical…
- 9VAW 2.24 Å, Cryo-EM structure of human Neurotensin Receptor 1 (hNTSR1)-Gq (delipidated) complex in…
- 9P80 2.3 Å, NTSR1-Gi-NTS(8-13) Complex in the Non-Canonical, AHD Open State (NC-Open-Apo)
- 20ZG 2.4 Å, Cryo-EM structure of the human neurotensin receptor 1 (hNTSR1)-Gi1 complex in the…
- 20ZH 2.4 Å, Cryo-EM structure of the human neurotensin receptor 1 (hNTSR1)-Gi1 complex in the…
- 7UL2 2.4 Å, CryoEM Structure of Inactive NTSR1 Bound to SR48692 and Nb6
- 9P82 2.4 Å, NTSR1-Gi-NTS(8-13) GTP-Bound Complex in the Canonical, AHD Closed State (C-Closed-GTP)
- 20ZC 2.6 Å, Cryo-EM structure of human Neurotensin Receptor 1 (hNTSR1)-Gi1 (delipidated) complex in…
- 9P81 2.6 Å, NTSR1-Gi-NTS(8-13), GTP-bound Complex in the Canonical, AHD Open State (C-Open-GTP)
- 8ZYT 2.65 Å, Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin1 and SBI-553…
Browse structure collections
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