2NWD: Chemically synthesized human lysozyme

Structure of chemically synthesized human lysozyme at 1 Angstrom resolution. Determined by X-ray diffraction at 1.04 Å resolution. Released 19 Dec 2006.

Method: X-ray diffraction
Resolution: 1.04 Å
Chains: 1
Atoms: 1,250
Mol. weight: 14.72 kDa
Released: 19 Dec 2006

Explore 2NWD in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2NWD contains 7 α-helices and 9 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain X: 7 helices, 9 β-strands

Element	Residues	Length	Sheet
β-strand	2	1	1
α-helix	5-14	10
β-strand	20	1	2
β-strand	23	1	2
α-helix	25-36	12
β-strand	39	1	1
β-strand	43-46	4	3
β-strand	51-54	4	3
β-strand	59-60	2	3
β-strand	66	1	4
β-strand	80	1	4
α-helix	81-85	5
α-helix	90-101	12
α-helix	105-108	4
α-helix	110-115	6
α-helix	122-124	3

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Lysozyme C	X	protein	130		P61626 (AlphaFold model)

Sequence of entity 1 (X), FASTA

>2NWD_1 Lysozyme C (chains X)
KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQIN
SRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRD
VRQYVQGCGV

Primary citation

Convergent chemical synthesis and high-resolution x-ray structure of human lysozyme. Durek, T., Torbeev, V.Y., Kent, S.B. Proc Natl Acad Sci U S A (2007) 104:4846-4851. DOI 10.1073/pnas.0610630104 · PubMed

Other PDB entries of the same protein (UniProt P61626 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5LSH 1.06 Å, human lysozyme in complex with a tetrasaccharide fragment of the O-chain of LPS from…
1JSF 1.15 Å, Full-matrix least-squares refinement of human lysozyme
7AP7 1.15 Å, Structure of the W64R amyloidogenic variant of human lysozyme
7XF6 1.3 Å, Crystal Structure of Human Lysozyme
1IWT 1.4 Å, Crystal Structure Analysis of Human lysozyme at 113K.
1IWU 1.4 Å, Crystal Structure Analysis of Human lysozyme at 127K.
1IWV 1.4 Å, Crystal Structure Analysis of Human lysozyme at 147K.
1IWW 1.4 Å, Crystal Structure Analysis of Human lysozyme at 152K.
1IWX 1.4 Å, Crystal Structure Analysis of Human lysozyme at 161K.
1IWY 1.4 Å, Crystal Structure Analysis of Human lysozyme at 170K.
1JWR 1.4 Å, Crystal structure of human lysozyme at 100 K
6LFH 1.46 Å, X-ray crystal structure of chemically synthesized human lysozyme

Browse structure collections

About this viewer

MolViewer shows 2NWD directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.