2OCW: Human secretory component

Solution structure of human secretory component. Determined by solution scattering. Released 10 Apr 2007.

Method

Solution scattering

Organism

Homo sapiens

Chains

1

Atoms

585

Mol. weight

64.36 kDa

Released

10 Apr 2007

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Molecules and chains

>2OCW_1 Polymeric-immunoglobulin receptor (chains A)
KSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKY
AGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTK
VYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGT
GQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCA
LGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKE
DAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGSSVAVLCPYNRKES
KSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGF
YWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKW
NNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAV
YVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPR

Primary citation

Solution structure of human secretory component and implications for biological function. Bonner, A., Perrier, C., Corthesy, B. et al. J Biol Chem (2007) 282:16969-16980. DOI 10.1074/jbc.M701281200 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P01833 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 1XED 1.9 Å, Crystal Structure of a Ligand-Binding Domain of the Human Polymeric Ig Receptor, pIgR
• 5D4K 2.6 Å, Crystal structure of the human polymeric Ig receptor (pIgR) ectodomain
• 6UE7 2.9 Å, Structure of dimeric sIgA complex
• 6UE9 2.9 Å, Structure of tetrameric sIgA complex (Class 2)
• 6UE8 3.0 Å, Structure of tetrameric sIgA complex (Class 1)
• 6UEA 3.0 Å, Structure of pentameric sIgA complex
• 8SKV 3.1 Å, Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4)
• 6LX3 3.15 Å, Cryo-EM structure of human secretory immunoglobulin A
• 7YSG 3.18 Å, Cryo-EM structure of human FcmR bound to sIgM
• 8SKU 3.2 Å, Structure of human SIgA1 in complex with human CD89 (FcaR1)
• 6LXW 3.27 Å, Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal…
• 7K0C 3.3 Å, Structure of Secretory IgM Core

Browse structure collections

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