31FZ: Mouse 80S ribosome, eL41 KO

Name: PDB 31FZ: Mouse 80S ribosome, eL41 KO
Published: 2026-09-23
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: ribosome

Mouse 80S ribosome, eL41 KO. Determined by electron microscopy at 2.89 Å resolution. Released 23 Sept 2026.

Method: Electron microscopy
Resolution: 2.89 Å
Organism: Mus musculus
Chains: 78
Atoms: 208,103
Mol. weight: 3679.79 kDa
Ligands: ZN
Released: 23 Sept 2026

Explore 31FZ in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

31FZ contains 560 α-helices and 516 β-strands across 74 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain Aa: 5 helices, 3 β-strands

Element	Residues	Length	Sheet
α-helix	7-10	4
β-strand	16-17	2	7
β-strand	27-28	2	7
β-strand	33-34	2	7
α-helix	44-45	2
α-helix	51-56	6
α-helix	67-74	8
α-helix	84-86	3

Chain AA: 11 helices, 19 β-strands

Element	Residues	Length	Sheet
α-helix	6-9	4
α-helix	10-12	3
α-helix	30-32	3
α-helix	34-38	5
β-strand	40-49	10	1
α-helix	50-51	2
β-strand	58-64	7	1
β-strand	71-77	7	1
α-helix	78	1
β-strand	79	1	2
β-strand	83	1	3
β-strand	87-91	5	1
β-strand	101-103	3	1
α-helix	104-106	3
α-helix	108	1
β-strand	112-114	3	1
β-strand	116-117	2	4
β-strand	120	1	5
β-strand	122	1	5
β-strand	125-126	2	4
β-strand	134-140	7	1
β-strand	145-149	5	1
β-strand	155-159	5	1
β-strand	163-166	4	1
β-strand	169	1	2
α-helix	174-176	3
α-helix	182-190	9
α-helix	201-203	3
β-strand	224-225	2	6
β-strand	237-238	2	6

Chain Ab: 3 helices, 5 β-strands

Element	Residues	Length	Sheet
β-strand	3-4	2	15
α-helix	8-16	9
β-strand	22-27	6	15
β-strand	32-37	6	15
β-strand	42-47	6	15
α-helix	51-59	9
α-helix	61	1
β-strand	65-68	4	15

Chain AB: 23 helices, 18 β-strands

Element	Residues	Length	Sheet
α-helix	9-10	2
α-helix	14-16	3
α-helix	27-28	2
α-helix	32-35	4
α-helix	40-41	2
β-strand	42-43	2	10
β-strand	45-59	15	11
β-strand	71-80	10	11
α-helix	82-83	2
β-strand	84-95	12	12
β-strand	98-106	9	12
α-helix	112-115	4
α-helix	116-118	3
α-helix	131-134	4
α-helix	135-137	3
α-helix	140-156	17
β-strand	159-165	7	12
α-helix	168-170	3
α-helix	178-179	2
β-strand	180-184	5	12
β-strand	185-186	2	10
α-helix	190-198	9
β-strand	204-205	2	12
α-helix	207-209	3
β-strand	216-222	7	11
α-helix	223-224	2
β-strand	225-229	5	13
α-helix	231-234	4
α-helix	237-241	5
β-strand	270-273	4	13
β-strand	276-288	13	11
β-strand	293-294	2	14
β-strand	297-298	2	14
α-helix	316	1
β-strand	330-334	5	11
β-strand	344-349	6	11
α-helix	357-360	4
α-helix	362-363	2
β-strand	364-368	5	11
α-helix	382-389	8
α-helix	393-402	10

Chain Ac: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	7-19	13
α-helix	22-24	3
α-helix	25-29	5

Chain AC: 24 helices, 11 β-strands

Element	Residues	Length	Sheet
β-strand	7-11	5	18
β-strand	17-23	7	18
α-helix	24-25	2
α-helix	26-29	4
α-helix	31-32	2
α-helix	34-44	11
α-helix	45-48	4
α-helix	49-51	3
β-strand	64-66	3	19
β-strand	77-79	3	19
β-strand	90	1	19
α-helix	117-130	14
α-helix	134-139	6
β-strand	152-154	3	18
α-helix	156-160	5
α-helix	164-174	11
α-helix	177-186	10
β-strand	188-189	2	20
α-helix	190-191	2
α-helix	193-197	5
β-strand	201-202	2	20
β-strand	208-211	4	18
α-helix	217-221	5
β-strand	228-231	4	18
α-helix	232-234	3
α-helix	237-240	4
β-strand	250-253	4	18
α-helix	254-264	11
α-helix	279-282	4
α-helix	289-294	6
α-helix	296-299	4
α-helix	302-305	4
α-helix	311-314	4
α-helix	322-328	7
α-helix	332-367	36

Chain Ad: 2 helices, 3 β-strands

Element	Residues	Length	Sheet
α-helix	80-90	11
β-strand	94-96	3	25
β-strand	102-103	2	25
β-strand	121-123	3	25
α-helix	124-127	4

Chain AD: 17 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	10-15	6
α-helix	21-24	4
α-helix	30-37	8
α-helix	38-40	3
β-strand	50-55	6	23
β-strand	60-66	7	23
β-strand	73-79	7	23
α-helix	80-82	3
α-helix	95-113	19
α-helix	134-135	2
α-helix	139-142	4
β-strand	145-147	3	23
α-helix	158-169	12
β-strand	183-184	2	24
β-strand	189-190	2	24
α-helix	194-200	7
α-helix	202-214	13
α-helix	217-222	6
α-helix	225-229	5
α-helix	236-249	14
α-helix	252-258	7
α-helix	268-272	5
α-helix	273-291	19

66 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Large ribosomal subunit protein uL2	AA	protein	257	Mus musculus	P62918 (AlphaFold model)
Large ribosomal subunit protein uL3	AB	protein	403	Mus musculus	P27659 (AlphaFold model)
Large ribosomal subunit protein uL4	AC	protein	419	Mus musculus	Q9D8E6 (AlphaFold model)
Large ribosomal subunit protein uL18	AD	protein	297	Mus musculus	P47962 (AlphaFold model)
Large ribosomal subunit protein eL6	AE	protein	296	Mus musculus	P47911
Large ribosomal subunit protein uL13	AF	protein	203	Mus musculus	P19253
Large ribosomal subunit protein uL22	AG	protein	184	Mus musculus	Q9CPR4
Large ribosomal subunit protein eL18	AH	protein	188	Mus musculus	P35980
Large ribosomal subunit protein eL19	AI	protein	196	Mus musculus	P84099
Large ribosomal subunit protein eL20	AJ	protein	176	Mus musculus	P62717
Large ribosomal subunit protein eL21	AK	protein	160	Mus musculus	O09167
Large ribosomal subunit protein eL22	AL	protein	128	Mus musculus	P67984

66 more molecules are not listed.

Sequence of entity 1 (AA), FASTA

>31FZ_1 Large ribosomal subunit protein uL2 (chains AA)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAA
RRTGRLRGTKTVQEKEN

Sequence of entity 2 (AB), FASTA

>31FZ_2 Large ribosomal subunit protein uL3 (chains AB)
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDASKPVHLTAFLGYKAGMTHIVREV
DRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYK
NWHKSKKKAFTKYCKKWQDDTGKKQLEKDFNSMKKYCQVIRIIAHTQMRLLPLRQKKAHL
MEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKL
PRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIK
NNASTDYDLSDKSINPLGGFVHYGEVTNDFIMLKGCVVGTKKRVLTLRKSLLVQTKRRAL
EKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA

Sequence of entity 3 (AC), FASTA

>31FZ_3 Large ribosomal subunit protein uL4 (chains AC)
MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGH
QTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQK
RYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVQLLKKLKAWNDI
KKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKL
APGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQR
ALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVKKLEAAATA
LATKSEKVVPEKGTADKKPAVGKKGKKVDAKKQKPAGKKVVAKKPAEKKPTTEEKKPAA

Sequence of entity 4 (AD), FASTA

>31FZ_4 Large ribosomal subunit protein uL18 (chains AD)
MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDI
ICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYE
GQVEVNGGEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRF
PGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMY
KKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES

Sequence of entity 5 (AE), FASTA

>31FZ_5 Large ribosomal subunit protein eL6 (chains AE)
MAGEKAPDTKEKKPAAKKAGSDAAASRPRAAKVAKKVHPKGKKPKKAKPHCSRNPVLVRG
IGRYSRSAMYSRKALYKRKYSAAKTKVEKKKKKEKVLATVTKTVGGDKNGGTRVVKLRKM
PRYYPTEDVPRKLLSHGKKPFSQHVRRLRSSITPGTVLIILTGRHRGKRVVFLKQLDSGL
LLVTGPLVINRVPLRRTHQKFVIATSTKVDISDVKIPKHLTDAYFKKKQLRKPRHQEGEI
FDTEKEKYEITEQRKADQKAVDLQILPKIKAVPQLQGYLRSQFSLTNGMYPHKLVF

Sequence of entity 6 (AF), FASTA

>31FZ_6 Large ribosomal subunit protein uL13 (chains AF)
MAEGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRK
RMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVV
PAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKMHYRKKKQILRLRKQ
AEKNVEKKICKFTEVLKTNGLLV

Sequence of entity 7 (AG), FASTA

>31FZ_7 Large ribosomal subunit protein uL22 (chains AG)
MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPF
RRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVN
KAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKL
MARE

Sequence of entity 8 (AH), FASTA

>31FZ_8 Large ribosomal subunit protein eL18 (chains AH)
MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPP
LSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCALRVSSRARSRILKAGGKI
LTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGR
RASRGYKN

Sequence of entity 9 (AI), FASTA

>31FZ_9 Large ribosomal subunit protein eL19 (chains AI)
MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSR
ARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMY
HSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAK
KEEIIKTLSKEEETKK

Sequence of entity 10 (AJ), FASTA

>31FZ_10 Large ribosomal subunit protein eL20 (chains AJ)
MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGE
IVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRAR
AHSIQIMKVEEIAAGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF

Sequence of entity 11 (AK), FASTA

>31FZ_11 Large ribosomal subunit protein eL21 (chains AK)
MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGK
TGRVYNVTQHAVGIIVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAK
EKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA

Sequence of entity 12 (AL), FASTA

>31FZ_12 Large ribosomal subunit protein eL22 (chains AL)
MAPVKKLVAKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGV
VTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQD
EEEEEDED

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	7

Primary citation

Gm10076 and eL41. Rabl, J., Valdivia Francia, F., Sendoel, A. To be published.

Other PDB entries of the same protein (UniProt P62918 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9H4N 2.46 Å, RPL13 (eL13)-mutant 80S ribosome from mouse
31FX 2.54 Å, Mouse 80S ribosome, sgRNA control
31FY 2.57 Å, Mouse 80S ribosome, Gm10076 KO
9KDT 2.63 Å, Cryo-EM structure of 80S ribosome
9KDW 2.67 Å, Cryo-EM structure of 80S ribosome
9QOH 2.78 Å, Mouse Ribosome POST translocation state
9QQP 2.8 Å, Mouse Ribosome rotated-2 PRE state
7CPU 2.82 Å, Cryo-EM structure of 80S ribosome from mouse kidney
9KDU 2.96 Å, Cryo-EM structure of 80S ribosome
7CPV 3.03 Å, Cryo-EM structure of 80S ribosome from mouse testis
9QQL 3.09 Å, Mouse RPS15 P131 Mutant Ribosome POST translocation state
6SWA 3.1 Å, Mus musculus brain neocortex ribosome 60S bound to Ebp1

Browse structure collections

About this viewer

MolViewer shows 31FZ directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.