9KDW: 80S ribosome
Cryo-EM structure of 80S ribosome. Determined by electron microscopy at 2.67 Å resolution. Released 13 May 2026.
- Method
- Electron microscopy
- Resolution
- 2.67 Å
- Organism
- Mus musculus
- Chains
- 81
- Atoms
- 204,125
- Mol. weight
- 3704.44 kDa
- Ligands
- MG, ZN
- Released
- 13 May 2026
Explore 9KDW in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9KDW contains 479 α-helices and 529 β-strands across 73 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain La: 9 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 7-10 | 4 | |
| α-helix | 42-48 | 7 | |
| α-helix | 65-68 | 4 | |
| β-strand | 72-73 | 2 | 20 |
| α-helix | 75-77 | 3 | |
| α-helix | 79-81 | 3 | |
| α-helix | 84-92 | 9 | |
| β-strand | 98 | 1 | 99 |
| β-strand | 100-102 | 3 | 21 |
| α-helix | 103-106 | 4 | |
| β-strand | 110-111 | 2 | 20 |
| β-strand | 123-126 | 4 | 21 |
| β-strand | 128-129 | 2 | 20 |
| α-helix | 131-140 | 10 | |
| β-strand | 145-146 | 2 | 21 |
Chain LA: 12 helices, 19 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 4-5 | 2 | |
| α-helix | 29-32 | 4 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 25 |
| α-helix | 50-51 | 2 | |
| β-strand | 58-64 | 7 | 25 |
| β-strand | 71-74 | 4 | 25 |
| α-helix | 76 | 1 | |
| β-strand | 77 | 1 | 25 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 26 |
| β-strand | 83 | 1 | 27 |
| β-strand | 87-91 | 5 | 25 |
| β-strand | 101-103 | 3 | 25 |
| α-helix | 104-106 | 3 | |
| β-strand | 112-113 | 2 | 28 |
| β-strand | 116 | 1 | 29 |
| β-strand | 126 | 1 | 29 |
| β-strand | 134-140 | 7 | 28 |
| β-strand | 145-149 | 5 | 28 |
| β-strand | 155-159 | 5 | 28 |
| β-strand | 163-165 | 3 | 25 |
| β-strand | 166 | 1 | 28 |
| β-strand | 169 | 1 | 26 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-189 | 8 | |
| α-helix | 198-200 | 3 | |
| α-helix | 201-203 | 3 | |
| β-strand | 224-225 | 2 | 30 |
| α-helix | 229-230 | 2 | |
| β-strand | 237-238 | 2 | 30 |
Chain Lb: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-15 | 4 | |
| α-helix | 22-26 | 5 | |
| α-helix | 37-48 | 12 | |
| α-helix | 54-68 | 15 | |
| α-helix | 90-97 | 8 | |
| α-helix | 104-113 | 10 | |
Chain LB: 19 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-10 | 3 | |
| α-helix | 14-16 | 3 | |
| α-helix | 33-35 | 3 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 33 |
| β-strand | 45-59 | 15 | 34 |
| β-strand | 71-80 | 10 | 34 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 35 |
| β-strand | 98-106 | 9 | 35 |
| α-helix | 112-115 | 4 | |
| α-helix | 116-118 | 3 | |
| α-helix | 131-134 | 4 | |
| α-helix | 135-137 | 3 | |
| α-helix | 140-156 | 17 | |
| β-strand | 159-165 | 7 | 35 |
| α-helix | 168-170 | 3 | |
| β-strand | 180-184 | 5 | 35 |
| β-strand | 185-186 | 2 | 33 |
| α-helix | 190-200 | 11 | |
| β-strand | 204-205 | 2 | 35 |
| α-helix | 207-209 | 3 | |
| β-strand | 216-222 | 7 | 34 |
| α-helix | 223-224 | 2 | |
| β-strand | 225-229 | 5 | 36 |
| α-helix | 231-234 | 4 | |
| α-helix | 237-241 | 5 | |
| β-strand | 270-273 | 4 | 36 |
| β-strand | 276-287 | 12 | 34 |
| β-strand | 292-293 | 2 | 37 |
| β-strand | 297-298 | 2 | 37 |
| α-helix | 300-302 | 3 | |
| β-strand | 320 | 1 | 38 |
| β-strand | 324 | 1 | 38 |
| β-strand | 330-334 | 5 | 34 |
| β-strand | 344-349 | 6 | 34 |
| β-strand | 365-368 | 4 | 34 |
| α-helix | 382-389 | 8 | |
| α-helix | 393-396 | 4 | |
Chain Lc: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-24 | 11 | |
| β-strand | 26-29 | 4 | 39 |
| α-helix | 31-40 | 10 | |
| β-strand | 45-48 | 4 | 39 |
| α-helix | 54-67 | 14 | |
| β-strand | 70-73 | 4 | 39 |
| α-helix | 78-85 | 8 | |
| β-strand | 93-98 | 6 | 39 |
Chain LC: 20 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 7-11 | 5 | 44 |
| β-strand | 17-23 | 7 | 44 |
| α-helix | 24-25 | 2 | |
| α-helix | 26-29 | 4 | |
| α-helix | 34-44 | 11 | |
| β-strand | 64-65 | 2 | 45 |
| β-strand | 78-79 | 2 | 45 |
| β-strand | 90 | 1 | 45 |
| α-helix | 117-130 | 14 | |
| α-helix | 134-138 | 5 | |
| β-strand | 152-154 | 3 | 44 |
| α-helix | 156-160 | 5 | |
| α-helix | 164-173 | 10 | |
| α-helix | 177-185 | 9 | |
| β-strand | 188-189 | 2 | 46 |
| α-helix | 193-197 | 5 | |
| β-strand | 201-202 | 2 | 46 |
| β-strand | 208-210 | 3 | 44 |
| α-helix | 217-220 | 4 | |
| β-strand | 228-229 | 2 | 44 |
| α-helix | 237-240 | 4 | |
| β-strand | 250-253 | 4 | 44 |
| α-helix | 254-257 | 4 | |
| α-helix | 260-264 | 5 | |
| α-helix | 279-282 | 4 | |
| α-helix | 289-293 | 5 | |
| α-helix | 296-299 | 4 | |
| α-helix | 302-305 | 4 | |
| α-helix | 316-317 | 2 | |
| α-helix | 322-328 | 7 | |
| α-helix | 331-357 | 27 | |
Chain Ld: 3 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 21-28 | 8 | 47 |
| α-helix | 38-40 | 3 | |
| α-helix | 41-56 | 16 | |
| β-strand | 62-64 | 3 | 47 |
| α-helix | 66-72 | 7 | |
| β-strand | 83-92 | 10 | 47 |
| β-strand | 102-108 | 7 | 47 |
| β-strand | 120-121 | 2 | 47 |
Chain LD: 11 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-15 | 6 | |
| α-helix | 21-24 | 4 | |
| α-helix | 32-37 | 6 | |
| β-strand | 50-55 | 6 | 49 |
| β-strand | 60-66 | 7 | 49 |
| β-strand | 73-79 | 7 | 49 |
| α-helix | 95-113 | 19 | |
| α-helix | 139-142 | 4 | |
| β-strand | 143 | 1 | 50 |
| β-strand | 145-147 | 3 | 49 |
| α-helix | 158-169 | 12 | |
| β-strand | 172 | 1 | 50 |
| β-strand | 184 | 1 | 51 |
| β-strand | 189 | 1 | 51 |
| α-helix | 194-200 | 7 | |
| α-helix | 202-213 | 12 | |
| α-helix | 218-222 | 5 | |
| α-helix | 236-249 | 14 | |
| α-helix | 273-293 | 21 | |
65 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Mus musculus 28S ribosomal RNA | L5 | RNA | 4731 | Mus musculus | |
| Mus musculus 5S ribosomal RNA | L7 | RNA | 120 | Mus musculus | |
| Mus musculus 5.8S ribosomal RNA | L8 | RNA | 158 | Mus musculus | |
| Large ribosomal subunit protein uL2 | LA | protein | 257 | Mus musculus | P62918 (AlphaFold model) |
| Large ribosomal subunit protein uL3 | LB | protein | 403 | Mus musculus | P27659 (AlphaFold model) |
| Large ribosomal subunit protein uL4 | LC | protein | 419 | Mus musculus | Q9D8E6 (AlphaFold model) |
| Large ribosomal subunit protein uL18 | LD | protein | 297 | Mus musculus | P47962 (AlphaFold model) |
| Large ribosomal subunit protein eL6 | LE | protein | 296 | Mus musculus | P47911 |
| Large ribosomal subunit protein uL30 | LF | protein | 270 | Mus musculus | P14148 |
| Large ribosomal subunit protein eL8 | LG | protein | 266 | Mus musculus | P12970 |
| Large ribosomal subunit protein uL6 | LH | protein | 192 | Mus musculus | P51410 |
| Large ribosomal subunit protein uL16-like | LI | protein | 214 | Mus musculus | P86048 |
68 more molecules are not listed.
Sequence of entity 1 (L5), FASTA
>9KDW_1 Mus musculus 28S ribosomal RNA (chains L5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAA
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCGCGCGUCGCGGCGUGGGAAAUGUGGCGUACGGAAGACCCACUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCGGCGCGCCGGGCUCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCAG
CCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAAC
AAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAAC
CGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGCG
GGCGUCCGGCCGUGCCCGGUGGUCCCGGCGGAUCUUUCCCGCUCCCCGUUCCUCCCGACC
CCUCCACCCGCGCGUCGUUCCCCUCUUCCUCCCCGCGUCCGGCGCCUCCGGCGGCGGGCG
CGGGGGGUGGUGUGGUGGUGGCGCGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGGACCG
UCCCCCGGCCGGCGACCGGCCGCCGCCGGGCGCACUUCCACCGUGGCGGUGCGCCGCGAC
CGGCUCCGGGACGGCCGGGAAGGCCCGGUGGGGAAGGUGGCUCGGGGGGGGCGGCGCGUC
UCAGGGCGCGCCGAACCACCUCACCCCGAGUGUUACAGCCCUCCGGCCGCGCUUUCGCCG
AAUCCCGGGGCCGAGGAAGCCAGAUACCCGUCGCCGCGCUCUCCCUCUCCCCCCGUCCGC
CUCCCGGGCGGGCGUGGGGGUGGGGGCCGGGCCGCCCCUCCCACGGCGCGACCGCUCUCC
CACCCCCCUCCGUCGCCUCUCUCGGGGCCCGGUGGGGGGCGGGGCGGACUGUCCCCAGUG
CGCCCCGGGCGUGGUCGCGCCGUCGGGUCCGGGGGGGACCGUCGGUCACGCGUCUCCCGA
CGAAGCCGAGCGCACGGGGUCGGCGGCGAUGUCGGCUACCCACCCGACCCGUCUUGAAAC
ACGGACCAAGGAGUCUAACGCGUGCGCGAGUCAGGGGCUCGUCCGAAAGCCGCCGUGGCG
CAAUGAAGGUGAAGGGCCCCGCCCGGGGGCCCGAGGUGGGAUCCCGAGGCCUCUCCAGUC
CGCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGCACGAGCG
UACGCGUUAGGACCCGAAAGAUGGUGAACUAUGCUUGGGCAGGGCGAAGCCAGAGGAAAC
UCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGGUCGUCCGACCUGGGUAUAGGG
GCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUCCGAAGUUUCCCUCAGGAUAGC
UGGCGCUCUCGCUCCCGACGUACGCAGUUUUAUCCGGUAAAGCGAAUGAUUAGAGGUCUU
GGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUAAGAAGCCCGGCUCGCU
GGCGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUUUUGGUAAGCAGAACUG
GCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCCGACGCUCAUCAGACCC
CAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCU
AAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAAAAUGGAUGGCGCUGGA
GCGUCGGGCCCAUACCCGGCCGUCGCCGGCAGUCGGAACGGAACGGGACGGGAGCGGCCG
CGGGUGCGCGUCUCUCGGGGUCGGGGGUGCGUGGCGGGGGCCCGUCCCCCGCCUCCCCUC
CGCGCGCCGGGUUCGCCCCCGCGGCGUCGGGCCCCGCGGACGCUACGCCGCGACGAGUAG
GAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCCGCAGG
UGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGUGGAGA
AGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGCGAGUG
CCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGCCCUCGGCCGAUCGAAAGGGAGUCGGG
UUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGGCGCCGCGAGGCCAGUGCGGUAACGCG
ACCGAUCCCGGAGAAGCCGGCGGGAGCCCCGGGGAGAGUUCUCUUUUCUUUGUGAAGGGC
AGGGCGCCCUGGAAUGGGUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAGCGUCGCGG
UUCCGGCGGCGUCCGGUGAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAGGGUGUAAA
UCUCGCGCCGGGCCGUACCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCCUCUGGCAU
GUUGGAACAAUGUAGGUAAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGGAUAAGGAU
UGGCUCUAAGGGCUGGGUCGGUCGGGCUGGGGCGCGAAGCGGGGCUGGGCGCGCGCCGCG
GCUGGACGAGGCGCCGCCGCCCUCUCCCACGUCCGGGGAGACCCCCCGUCCUUUCCGCCC
GGGCCCGCCCUCCCCUCUUCCCCGCGGGGCCCCGUCGUCCCCCGCGUCGUCGCCACCUCU
CUUCCCCCCUCCUUCUUCCCGUCGGGGGGCGGGUCGGGGGUCGGCGCGCGGCGCGGGCUC
CGGGGCGGCGGGUCCAACCCCGCGGGGGUUCCGGAGCGGGAGGAACCAGCGGUCCCCGGU
GGGGCGGGGGGCCCGGACACUCGGGGGGCCGGCGGCGGCGGCGACUCUGGACGCGAGCCG
GGCCCUUCCCGUGGAUCGCCUCAGCUGCGGCGGGCGUCGCGGCCGCUCCCGGGGAGCCCG
GCGGGUGCCGGCGCGGGUCCCCUCCCCGCGGGGCCUCGCUCCACCCCCCCAUCGCCUCUC
CCGAGGUGCGUGGCGGGGGCGGGCGGGCGUGUCCCGCGCGUGUGGGGGGAACCUCCGCGU
CGGUGUUCCCCCGCCGGGUCCGCCCCCCGGGCCGCGGUUUUCCGCGCGGCGCCCCCGCCU
CGGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACCAGGGGAAUCCGACUGUUUAA
UUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAUGUGAUUUCUGCCCAG
UGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAACGGCGGGAGUAACUA
UGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUG
AACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAGCCAAGGGAACGGGCU
UGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCUGGCACGGUGAA
GAGACAUGAGAGGUGUAGAAUAAGUGGGAGGCCCCCGGCGCCCGGCCCCGUCCUCGCGUC
GGGGUCGGGGCACGCCGGCCUCGCGGGCCGCCGGUGAAAUACCACUACUCUCAUCGUUUU
UUCACUGACCCGGUGAGGCGGGGGGGCGAGCCCCGAGGGGCUCUCGCUUCUGGCGCCAAG
CGUCCGUCCCGCGCGUGCGGGCGGGCGCGACCCGCUCCGGGGACAGUGCCAGGUGGGGAG
UUUGACUGGGGCGGUACACCUGUCAAACGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGG
AGGACAGAAACCUCCCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUA
CGAAUACAGACCGUGAAAGCGGGGCCUCACGAUCCUUCUGACCUUUUGGGUUUUAAGCAG
GAGGUGUCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCG
ACGUCGCUUUUUGAUCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCA
AGCGUUGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGAC
AGGUUAGUUUUACCCUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGA
GGAACCGCAGGUUCAGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGC
UACCAUCUGUGGGAUUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGA
UACGGCAGCGCCGAAGGAGCCUCGGUUGGCCCCGGAUAGCCGGGUCCCCGUCCGUCCCCG
CUCGGCGGGGUCCCCGCGUCGUCCCCGCGGCGGCGCGGGGUCUCCCCCCGCCGGGCGUCG
GGACCGGGGUCCGGUGCGGAGAGCCGUUCGUCUUGGGAAACGGGGUGCGGCCGGAAAGGC
GGCCGCCCUCUCGCCCGUCACGUUGAACGCACGUUCGUGUGGAACCUGGCGCUAAACCAU
UCGUAGACGACCUGCUUCUGGGUCGGGGUUUCGUACGUAGCAGAGCAGCUCCCUCGCUGC
GAUCUAUUGAAAGUCAGCCCUCGACACAAGGGUUUGUCUCUGCGGGCUUUC
Sequence of entity 2 (L7), FASTA
>9KDW_2 Mus musculus 5S ribosomal RNA (chains L7)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
Sequence of entity 3 (L8), FASTA
>9KDW_3 Mus musculus 5.8S ribosomal RNA (chains L8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCUUG
Sequence of entity 4 (LA), FASTA
>9KDW_4 Large ribosomal subunit protein uL2 (chains LA)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAA
RRTGRLRGTKTVQEKEN
Sequence of entity 5 (LB), FASTA
>9KDW_5 Large ribosomal subunit protein uL3 (chains LB)
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDASKPVHLTAFLGYKAGMTHIVREV
DRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYK
NWHKSKKKAFTKYCKKWQDDTGKKQLEKDFNSMKKYCQVIRIIAHTQMRLLPLRQKKAHL
MEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKL
PRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIK
NNASTDYDLSDKSINPLGGFVHYGEVTNDFIMLKGCVVGTKKRVLTLRKSLLVQTKRRAL
EKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA
Sequence of entity 6 (LC), FASTA
>9KDW_6 Large ribosomal subunit protein uL4 (chains LC)
MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGH
QTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQK
RYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVQLLKKLKAWNDI
KKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKL
APGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQR
ALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVKKLEAAATA
LATKSEKVVPEKGTADKKPAVGKKGKKVDAKKQKPAGKKVVAKKPAEKKPTTEEKKPAA
Sequence of entity 7 (LD), FASTA
>9KDW_7 Large ribosomal subunit protein uL18 (chains LD)
MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDI
ICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYE
GQVEVNGGEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRF
PGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMY
KKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES
Sequence of entity 8 (LE), FASTA
>9KDW_8 Large ribosomal subunit protein eL6 (chains LE)
MAGEKAPDTKEKKPAAKKAGSDAAASRPRAAKVAKKVHPKGKKPKKAKPHCSRNPVLVRG
IGRYSRSAMYSRKALYKRKYSAAKTKVEKKKKKEKVLATVTKTVGGDKNGGTRVVKLRKM
PRYYPTEDVPRKLLSHGKKPFSQHVRRLRSSITPGTVLIILTGRHRGKRVVFLKQLDSGL
LLVTGPLVINRVPLRRTHQKFVIATSTKVDISDVKIPKHLTDAYFKKKQLRKPRHQEGEI
FDTEKEKYEITEQRKADQKAVDLQILPKIKAVPQLQGYLRSQFSLTNGMYPHKLVF
Sequence of entity 9 (LF), FASTA
>9KDW_9 Large ribosomal subunit protein uL30 (chains LF)
MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFA
LKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGI
NGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRG
YGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRG
GMKKKTTHFVEGGDAGNREDQINRLIRRMN
Sequence of entity 10 (LG), FASTA
>9KDW_10 Large ribosomal subunit protein eL8 (chains LG)
MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRY
IRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEK
KAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVP
YCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGN
VLGPKSVARIAKLEKAKAKELATKLG
Sequence of entity 11 (LH), FASTA
>9KDW_11 Large ribosomal subunit protein uL6 (chains LH)
MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKW
WGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGE
KYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIY
VSEKGTVQQADE
Sequence of entity 12 (LI), FASTA
>9KDW_12 Large ribosomal subunit protein uL16-like (chains LI)
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL
SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG
KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE
FEDKVAAKRLIPDGCGVKYIPERGPLDKWRALHS
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| MG | Magnesium ion | Mg | 97 |
| ZN | Zinc ion | Zn | 3 |
Primary citation
Cryo-EM structure of 80S ribosome. Lu, Y., Wang, X., Qin, Y. et al. To be published.
Other PDB entries of the same protein (UniProt P62918 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9H4N 2.46 Å, RPL13 (eL13)-mutant 80S ribosome from mouse
- 31FX 2.54 Å, Mouse 80S ribosome, sgRNA control
- 31FY 2.57 Å, Mouse 80S ribosome, Gm10076 KO
- 9KDT 2.63 Å, Cryo-EM structure of 80S ribosome
- 9QOH 2.78 Å, Mouse Ribosome POST translocation state
- 9QQP 2.8 Å, Mouse Ribosome rotated-2 PRE state
- 7CPU 2.82 Å, Cryo-EM structure of 80S ribosome from mouse kidney
- 31FZ 2.89 Å, Mouse 80S ribosome, eL41 KO
- 9KDU 2.96 Å, Cryo-EM structure of 80S ribosome
- 7CPV 3.03 Å, Cryo-EM structure of 80S ribosome from mouse testis
- 9QQL 3.09 Å, Mouse RPS15 P131 Mutant Ribosome POST translocation state
- 6SWA 3.1 Å, Mus musculus brain neocortex ribosome 60S bound to Ebp1
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