3AZD: Tropomyosin N-terminal fragment

Crystal structure of tropomyosin N-terminal fragment at 0.98A resolution. Determined by X-ray diffraction at 0.98 Å resolution. Released 19 Oct 2011.

Method: X-ray diffraction
Resolution: 0.98 Å
Organisms: Rattus norvegicus, Saccharomyces cerevisiae S288c
Chains: 2
Atoms: 595
Mol. weight: 8.55 kDa
Released: 19 Oct 2011

Explore 3AZD in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3AZD contains 3 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 2 helices, 0 β-strands

Element	Residues	Length	Sheet
α-helix	7-19	13
α-helix	24-31	8

Chain B: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	7-34	28

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
short alpha-tropomyosin,transcription factor GCN4	A, B	protein	37	Rattus norvegicus, Saccharomyces cerevisiae S288c	P03069 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>3AZD_1 short alpha-tropomyosin,transcription factor GCN4 (chains A, B)
AGSSSLEAVRRKIRSLQEQNYHLENEVARLKKLVGER

Primary citation

Structure of a tropomyosin N-terminal fragment at 0.98 A resolution. Meshcheryakov, V.A., Krieger, I., Kostyukova, A.S. et al. Acta Crystallogr D Biol Crystallogr (2011) 67:822-825. DOI 10.1107/S090744491102645X · PubMed

Other PDB entries of the same protein (UniProt P03069 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2WQ1 1.08 Å, GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating bromide
2WQ0 1.12 Å, GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating chloride
4OWI 1.2 Å, peptide structure
2WQ3 1.22 Å, GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating chloride and nitrate
2HY6 1.25 Å, A seven-helix coiled coil
2WPZ 1.25 Å, GCN4 leucine zipper mutant with two VxxNxxx motifs coordinating chloride
6PSA 1.3 Å, PIE12 D-peptide against HIV entry (in complex with IQN17 Q577R resistance mutant)
2IPZ 1.35 Å, A Parallel Coiled-Coil Tetramer with Offset Helices
2YNY 1.35 Å, Salmonella enterica SadA 255-302 fused to GCN4 adaptors (SadAK1)
5APU 1.35 Å, Sequence IANKEDKAD inserted between GCN4 adaptors - Structure A9b black
2WQ2 1.36 Å, GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating iodide
5APS 1.37 Å, Sequence IENKKAD inserted between GCN4 adaptors - Structure A7

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