3I4R: Nuclear pore complex protein Nup107

Nup107(aa658-925)/Nup133(aa517-1156) complex, H.sapiens. Determined by X-ray diffraction at 3.53 Å resolution. Released 11 Aug 2009.

Method
X-ray diffraction
Resolution
3.53 Å
Organism
Homo sapiens
Chains
2
Atoms
5,161
Mol. weight
106.09 kDa
Released
11 Aug 2009

Explore 3I4R in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3I4R contains 49 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 14 helices, 0 β-strands

ElementResiduesLengthSheet
α-helix668-68013
α-helix682-6843
α-helix685-70016
α-helix705-71410
α-helix719-7235
α-helix738-76730
α-helix770-7767
α-helix782-82140
α-helix837-8382
α-helix840-86728
α-helix871-8755
α-helix877-8826
α-helix888-8914
α-helix894-91320
Chain B: 35 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix522-5254
α-helix544-5496
α-helix562-5698
α-helix599-6079
α-helix613-6164
α-helix639-65012
α-helix662-67110
α-helix687-6904
α-helix694-6963
α-helix724-73411
α-helix737-7404
α-helix779-7879
α-helix797-8026
α-helix806-82217
α-helix830-8323
α-helix835-8417
α-helix850-8534
α-helix859-8657
α-helix870-87910
α-helix885-8917
α-helix897-9004
α-helix902-9054
α-helix922-9243
α-helix926-9305
α-helix936-9427
α-helix946-95914
α-helix964-98017
α-helix985-100622
α-helix1012-10154
α-helix1028-10347
α-helix1045-10495
α-helix1066-107914
α-helix1096-11038
α-helix1125-11284
α-helix1144-11474

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Nuclear pore complex protein Nup107Aprotein277Homo sapiensP57740 (AlphaFold model)
Nuclear pore complex protein Nup133Bprotein644Homo sapiensQ8WUM0 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>3I4R_1 Nuclear pore complex protein Nup107 (chains A)
GSPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKI
PQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPA
LIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVRED
AKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKE
ELRKLLQKLRESSLMLLDQGLDPLGYEIQLSGRIVTD
Sequence of entity 2 (B), FASTA
>3I4R_2 Nuclear pore complex protein Nup133 (chains B)
GSHMDKIKLLKAAFLQYCRKDLGHAQMVVDELFSSHSDLDSDSELDRAVTQISVDLMDDY
PASDPRWAESVPEEAPGFSNTSLIILHQLEDKMKAHSFLMDFIHQVGLFGRLGSFPVRGT
PMATRLLLCEHAEKLSAAIVLKNHHSRLSDLVNTAILIALNKREYEIPSNLTPADVFFRE
VSQVDTICECLLEHEEQVLRDAPMDSIEWAEVVINVNNILKDMLQAASHYRQNRNSLYRR
EESLEKEPEYVPWTATSGPGGIRTVIIRQHEIVLKVAYPQADSNLRNIVTEQLVALIDCF
LDGYVSQLKSVDKSSNRERYDNLEMEYLQKRSDLLSPLLSLGQYLWAASLAEKYCDFDIL
VQMCEQTDNQSRLQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQLANFLQAH
EHLSWLHEINSQELEKAHATLLGLANMETRYFAKKKTLLGLSKLAALASDFSEDMLQEKI
EEMAEQERFLLHQETLPEQLLAEKQLNLSAMPVLTAPQLIGLYICEENRRANEYDFKKAL
DLLEYIDEEEDININDLKLEILCKALQRDNWSSSDGKDDPIEVSKDSIFVKILQKLLKDG
IQLSEYLPEVKDLLQADQLGSLKSNPYFEFVLKANYEYYVQGQI

Primary citation

Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. Whittle, J.R., Schwartz, T.U. J Biol Chem (2009) 284:28442-28452. DOI 10.1074/jbc.M109.023580 · PubMed

Other PDB entries of the same protein (UniProt P57740 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

About this viewer

MolViewer shows 3I4R directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.