3LDD: Calcium-gated potassium channel mthK

High resolution open MthK pore structure crystallized in 100 mM K+ and further soaked in 99 mM Na+/1 mM K+. Determined by X-ray diffraction at 1.45 Å resolution. Released 11 Aug 2010.

Method: X-ray diffraction
Resolution: 1.45 Å
Organism: Methanothermobacter thermautotrophicus
Chains: 1
Atoms: 702
Mol. weight: 9.25 kDa
Released: 11 Aug 2010

Explore 3LDD in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

3LDD contains 3 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	20-42	23
α-helix	46-57	12
α-helix	70-98	29

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Calcium-gated potassium channel mthK	A	protein	82	Methanothermobacter thermautotrophicus	O27564 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>3LDD_1 Calcium-gated potassium channel mthK (chains A)
VPATRILLLVLAVIIYGTAGFHFIEGESWTVSLYWTFVTIATVGYGDYSPRTPLGMYFTC
TLIVLGIGTFAVAVERLLEFLI

Primary citation

Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore. Ye, S., Li, Y., Jiang, Y. Nat Struct Mol Biol (2010) 17:1019-1023. DOI 10.1038/nsmb.1865 · PubMed

Other PDB entries of the same protein (UniProt O27564 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3LDC 1.45 Å, High resolution open MthK pore structure crystallized in 100 mM K+
6U9T 1.55 Å, Wild-type MthK pore in 50 mM K+
4HYO 1.65 Å, Crystal Structure of MthK Pore
6U9P 1.65 Å, Wild-type MthK pore in ~150 mM K+
2AEF 1.7 Å, Crystal Structures of the MthK RCK Domain in Ca2+ bound form
4HZ3 1.7 Å, MthK pore crystallized in presence of TBSb
3OUS 1.75 Å, MthK channel pore T59A mutant
3R65 1.8 Å, MthK channel pore E92Q mutant
6U9Y 1.8 Å, Wild-type MthK pore in 11 mM K+
4L74 1.84 Å, Ca2+-bound MthK RCK domain at 1.9 Angstrom with single ligand
6U9Z 1.95 Å, Wild-type MthK pore in 6 mM K+
2AEJ 2.1 Å, Crystal Structures of the MthK RCK Domain in no Ca2+ bound form

Browse structure collections

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