S25-2- A(2-4)KDO disaccharide complex. Determined by X-ray diffraction at 1.74 Å resolution. Released 24 Aug 2011.
Explore 3T77 in 3D Show helices and sheets RCSB PDB PDBe
3T77 contains 18 α-helices and 46 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 4-7 | 4 | 1 |
| β-strand | 10-14 | 5 | 2 |
| β-strand | 19-25 | 7 | 1 |
| β-strand | 30 | 1 | 3 |
| β-strand | 31 | 1 | 3 |
| β-strand | 33-38 | 6 | 2 |
| β-strand | 45-49 | 5 | 2 |
| β-strand | 53-54 | 2 | 2 |
| α-helix | 55 | 1 | |
| β-strand | 62-67 | 6 | 1 |
| β-strand | 70-75 | 6 | 1 |
| α-helix | 80-82 | 3 | |
| β-strand | 84-90 | 7 | 2 |
| β-strand | 96-97 | 2 | 2 |
| β-strand | 101-106 | 6 | 2 |
| β-strand | 110 | 1 | 4 |
| α-helix | 111-112 | 2 | |
| β-strand | 113-117 | 5 | 5 |
| α-helix | 118-120 | 3 | |
| α-helix | 121-125 | 5 | |
| β-strand | 128-138 | 11 | 5 |
| β-strand | 139 | 1 | 4 |
| β-strand | 144-149 | 6 | 6 |
| β-strand | 152-154 | 3 | 6 |
| β-strand | 158-162 | 5 | 5 |
| α-helix | 163-166 | 4 | |
| β-strand | 172-181 | 10 | 5 |
| α-helix | 182-185 | 4 | |
| β-strand | 190-196 | 7 | 6 |
| α-helix | 203 | 1 | |
| β-strand | 204-209 | 6 | 6 |
| α-helix | 210-212 | 3 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 3-7 | 5 | 7 |
| β-strand | 11-12 | 2 | 8 |
| β-strand | 18-25 | 8 | 7 |
| α-helix | 29-31 | 3 | |
| β-strand | 34-39 | 6 | 9 |
| β-strand | 46-51 | 6 | 9 |
| α-helix | 52B-52D | 3 | |
| β-strand | 55-57 | 3 | 9 |
| β-strand | 65-70 | 6 | 7 |
| β-strand | 75-80 | 6 | 7 |
| α-helix | 84-86 | 3 | |
| β-strand | 88-94 | 7 | 9 |
| β-strand | 100E-101 | 2 | 9 |
| β-strand | 105-107 | 3 | 9 |
| β-strand | 108-109 | 2 | 8 |
| α-helix | 113-114 | 2 | |
| β-strand | 115 | 1 | 10 |
| α-helix | 116-117 | 2 | |
| β-strand | 118-122 | 5 | 11 |
| β-strand | 133-143 | 11 | 11 |
| β-strand | 144 | 1 | 10 |
| β-strand | 149-152 | 4 | 12 |
| α-helix | 153-155 | 3 | |
| β-strand | 157 | 1 | 12 |
| β-strand | 161-163 | 3 | 11 |
| α-helix | 164-166 | 3 | |
| β-strand | 167-169 | 3 | 11 |
| β-strand | 172-182 | 11 | 11 |
| α-helix | 183-185 | 3 | |
| β-strand | 192-197 | 6 | 12 |
| α-helix | 198-200 | 3 | |
| β-strand | 202-207 | 6 | 12 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| S25-2 FAB (IGG1K) light chain | A | protein | 219 | Mus musculus | Q52L64 (AlphaFold model) |
| S25-2 FAB (IGG1K) heavy chain | B | protein | 224 | Mus musculus |
>3T77_1 S25-2 FAB (IGG1K) light chain (chains A) DIVMSQSPSSLAVSAGEKVTMSCKSSQSLLNSRTRKNYLAWYQQKPGQSPKLLIYWASTR ESGVPDRFTGSGSGTDFTLTITSVQAEDLAVYYCKQSYNLRTFGGGTKLEIKRADAAPTV SIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSM SSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
>3T77_2 S25-2 FAB (IGG1K) heavy chain (chains B) EVKLVESGGGLVQSGGSLRLSCATSGFTFTDYYMSWVRQPPGKALEWLGFIRNKANGYTT EYSPSVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCARDHDGYYERFSYWGQGTLVTV SAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQ SDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDC
Germline antibody recognition of distinct carbohydrate epitopes. Nguyen, H.P., Seto, N.O., MacKenzie, C.R. et al. Nat Struct Biol (2003) 10:1019-1025. DOI 10.1038/nsb1014 · PubMed
Other PDB entries of the same protein (UniProt Q52L64 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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