4A8D: DegP dodecamer with bound OMP

DegP dodecamer with bound OMP. Determined by electron microscopy at 28.0 Å resolution. Released 11 Jan 2012.

Method

Electron microscopy

Resolution

28.0 Å

Organism

ESCHERICHIA COLI

Chains

13

Atoms

4,954

Mol. weight

600.57 kDa

Released

11 Jan 2012

Explore 4A8D in 3D Show helices and sheets RCSB PDB PDBe

Molecules and chains

>4A8D_1 PERIPLASMIC SERINE ENDOPROTEASE DEGP (chains A, B, C, D, E, F, G, H, I, J, K, L)
AETSSATTAQQMPSLAPMLEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEG
SPFQSSPFCQGGQGGNGGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDG
RKFDAKMVGKDPRSDIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSG
IVSALGRSGLNAENYENFIQTDAAINRGNAGGALVNLNGELIGINTAILAPDGGNIGIGF
AIPSNMVKNLTSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAA
KAGIKAGDVITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQN
QVDSSSIFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAE
LRKVLDSKPSVLALNIQRGDSTIYLLMQ

>4A8D_2 OUTER MEMBRANE PROTEIN C (chains M)
AEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQI
QGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNF
MQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGNPSGEGFTSGVTNNGRDALRQNGDGV
GGSITYDYEGFGIGGAISSSKRTDAQNTAAYIGNGDRAETYTGGLKYDANNIYLAAQYTQ
TYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDV
GATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Primary citation

Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq. Malet, H., Canellas, F., Sawa, J. et al. Nat Struct Mol Biol (2012) 19:152. DOI 10.1038/NSMB.2210 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P0C0V0 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 8F0A 2.6 Å, Client-bound structure of a DegP trimer within a 12mer cage
• 1KY9 2.8 Å, Crystal Structure of DegP (HtrA)
• 3MH7 2.96 Å, HtrA proteases are activated by a conserved mechanism that can be triggered by distinct…
• 3CS0 3.0 Å, Crystal structure of DegP24
• 3MH5 3.0 Å, HtrA proteases are activated by a conserved mechanism that can be triggered by distinct…
• 3OU0 3.0 Å, re-refined 3CS0
• 3MH4 3.1 Å, HtrA proteases are activated by a conserved mechanism that can be triggered by distinct…
• 8F0U 3.1 Å, Structure of a 12mer DegP cage bound to the client protein hTRF1
• 3MH6 3.6 Å, HtrA proteases are activated by a conserved mechanism that can be triggered by distinct…
• 6JJK 3.6 Å, Crystal structure of the DegP dodecamer with a modulator
• 3OTP 3.76 Å, Crystal structure of the DegP dodecamer with a model substrate
• 6JJO 4.16 Å, Crystal structure of the DegP dodecamer with a modulator

Browse structure collections

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