4BBS: DNA-directed RNA polymerase II subunit RPB1

Structure of an initially transcribing RNA polymerase II-TFIIB complex. Determined by X-ray diffraction at 3.6 Å resolution. Released 14 Nov 2012.

Method: X-ray diffraction
Resolution: 3.6 Å
Organism: SACCHAROMYCES CEREVISIAE
Chains: 16
Atoms: 33,420
Mol. weight: 567.51 kDa
Ligands: ZN, MG
Released: 14 Nov 2012

Explore 4BBS in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4BBS contains 198 α-helices and 246 β-strands across 13 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 84 helices, 72 β-strands

Element	Residues	Length	Sheet
α-helix	10	1
β-strand	11	1	1
β-strand	16-21	6	2
α-helix	24-30	7
β-strand	41	1	3
β-strand	49	1	3
β-strand	82-91	10	4
α-helix	93-95	3
α-helix	96-105	10
β-strand	106	1	5
β-strand	113	1	5
α-helix	120-125	6
α-helix	131-142	12
β-strand	147	1	6
β-strand	152-153	2	7
β-strand	161-162	2	7
α-helix	169	1
β-strand	170	1	6
α-helix	171-172	2
β-strand	175-177	3	8
β-strand	180-185	6	8
β-strand	198-202	5	8
α-helix	204-213	10
α-helix	216-221	6
β-strand	225	1	9
β-strand	229	1	9
α-helix	231-234	4
β-strand	235-241	7	4
α-helix	242-243	2
α-helix	244-246	3
β-strand	250-251	2	10
β-strand	257-260	4	10
α-helix	261-281	21
α-helix	286-288	3
α-helix	289-304	16
β-strand	310	1	11
α-helix	312-313	2
β-strand	314-316	3	12
β-strand	320-321	2	12
α-helix	322	1
α-helix	325-329	5
α-helix	335-339	5
β-strand	343-345	3	13
β-strand	348-355	8	14
β-strand	363-367	5	14
α-helix	368-373	6
β-strand	375-379	5	15
α-helix	385-394	10
β-strand	402-406	5	15
β-strand	412-414	3	15
α-helix	421-423	3
β-strand	431-435	5	15
α-helix	436	1
β-strand	441-445	5	14
α-helix	452-454	3
β-strand	455-463	9	14
β-strand	468-470	3	14
α-helix	472-474	3
α-helix	475-478	4
β-strand	486-490	5	14
α-helix	495-500	6
α-helix	501-505	5
β-strand	506	1	14
α-helix	507-511	5
β-strand	512-513	2	16
β-strand	518-519	2	16
α-helix	525-535	11
β-strand	540-542	3	17
α-helix	543-552	10
α-helix	560-563	4
β-strand	565-567	3	17
β-strand	571-573	3	17
α-helix	574-578	5
α-helix	583	1
β-strand	588-589	2	18
β-strand	606-607	2	18
β-strand	612-614	3	18
α-helix	619-622	4
α-helix	629-637	9
α-helix	639-660	22
β-strand	663	1	19
α-helix	666-669	4
α-helix	673-698	26
α-helix	702-705	4
α-helix	710-736	27
α-helix	742-749	8
α-helix	755-758	4
α-helix	759-763	5
β-strand	766-767	2	20
β-strand	769-770	2	21
β-strand	773-774	2	21
α-helix	775-776	2
β-strand	799-800	2	20
α-helix	810-845	36
β-strand	849-850	2	22
β-strand	856-857	2	22
β-strand	863-865	3	22
α-helix	868-870	3
β-strand	873	1	23
α-helix	875-877	3
β-strand	878-882	5	24
α-helix	884-886	3
α-helix	890-897	8
β-strand	913	1	25
α-helix	914-916	3
α-helix	923-946	24
β-strand	953-957	5	24
α-helix	960-971	12
β-strand	979	1	25
α-helix	983-994	12
α-helix	1005-1014	10
α-helix	1016-1025	10
α-helix	1028-1030	3
α-helix	1031-1035	5
α-helix	1039-1055	17
β-strand	1057	1	23
α-helix	1058-1059	2
α-helix	1064-1073	10
α-helix	1074-1076	3
α-helix	1098-1106	9
β-strand	1116-1119	4	26
β-strand	1120	1	27
α-helix	1123-1125	3
α-helix	1128-1138	11
β-strand	1141-1142	2	28
α-helix	1143-1146	4
β-strand	1147-1154	8	29
α-helix	1164-1166	3
α-helix	1167-1172	6
β-strand	1191-1197	7	29
α-helix	1199-1204	6
α-helix	1209-1217	9
α-helix	1221-1223	3
β-strand	1226-1228	3	29
β-strand	1236-1240	5	29
α-helix	1261-1270	10
β-strand	1272-1274	3	28
β-strand	1281-1287	7	26
β-strand	1290-1292	3	30
β-strand	1298-1300	3	30
β-strand	1303-1309	7	26
α-helix	1313-1318	6
β-strand	1322	1	27
β-strand	1328-1329	2	26
α-helix	1332-1339	8
α-helix	1341-1358	18
α-helix	1365-1376	12
α-helix	1389-1391	3
α-helix	1396-1399	4
α-helix	1400-1404	5
α-helix	1405-1414	10
β-strand	1418-1419	2	2
α-helix	1424-1429	6
α-helix	1437-1439	3
β-strand	1441-1445	5	31
α-helix	1447-1453	7

Chain B: 56 helices, 89 β-strands

Element	Residues	Length	Sheet
α-helix	23	1
β-strand	24	1	32
α-helix	25	1
α-helix	30-40	11
α-helix	45-53	9
α-helix	54-58	5
α-helix	59-64	6
β-strand	69-74	6	33
β-strand	85-90	6	33
β-strand	91-100	10	34
β-strand	101-103	3	35
β-strand	109-111	3	35
α-helix	114-119	6
β-strand	125-133	9	34
β-strand	136-139	4	33
β-strand	164-171	8	34
α-helix	172	1
β-strand	173	1	36
α-helix	180-183	4
α-helix	186-191	6
β-strand	203-205	3	36
β-strand	208-211	4	36
α-helix	212-213	2
β-strand	214-218	5	37
α-helix	219	1
β-strand	223-227	5	38
β-strand	234-240	7	38
β-strand	255-259	5	38
β-strand	269-272	4	38
β-strand	280-281	2	38
α-helix	282-287	6
α-helix	294-301	8
α-helix	308-320	13
α-helix	327-336	10
α-helix	347-358	12
α-helix	372-389	18
α-helix	394-397	4
α-helix	401-403	3
β-strand	404-407	4	37
α-helix	409-437	29
α-helix	444-447	4
α-helix	451-463	13
β-strand	465	1	39
α-helix	476	1
β-strand	477	1	39
β-strand	481-482	2	36
α-helix	483-484	2
α-helix	488-495	8
β-strand	497-499	3	37
α-helix	516-518	3
β-strand	522	1	40
β-strand	533	1	41
β-strand	536	1	41
β-strand	537-538	2	37
β-strand	539	1	40
β-strand	540	1	42
β-strand	544-545	2	43
α-helix	552-559	8
β-strand	564-565	2	44
α-helix	566-568	3
α-helix	577	1
β-strand	578-582	5	44
β-strand	585-590	6	44
α-helix	593-604	12
β-strand	614-618	5	44
β-strand	623-627	5	44
β-strand	633-639	7	43
β-strand	640-641	2	45
β-strand	650-651	2	45
β-strand	654	1	32
α-helix	655-666	12
α-helix	681-686	6
β-strand	690-694	5	43
α-helix	697-700	4
β-strand	703-704	2	43
α-helix	713-714	2
α-helix	728-729	2
β-strand	740-741	2	43
α-helix	745-748	4
β-strand	750	1	42
α-helix	753-755	3
α-helix	759-761	3
β-strand	762	1	46
α-helix	764-773	10
β-strand	777	1	47
β-strand	779	1	48
β-strand	793-796	4	48
β-strand	800	1	49
β-strand	804-805	2	50
α-helix	807-810	4
β-strand	821-827	7	51
β-strand	828	1	19
β-strand	839-842	4	51
α-helix	843-847	5
β-strand	853-862	10	48
β-strand	865-866	2	52
β-strand	870-871	2	52
β-strand	873-874	2	53
β-strand	882-883	2	53
β-strand	886	1	54
β-strand	898	1	55
α-helix	899-900	2
β-strand	901	1	56
β-strand	903	1	56
β-strand	904	1	48
β-strand	910-912	3	55
β-strand	914-917	4	53
β-strand	934-936	3	53
β-strand	939-940	2	55
α-helix	941-942	2
β-strand	948-956	9	48
β-strand	962-972	11	48
β-strand	979-982	4	51
β-strand	987-994	8	51
β-strand	1001-1002	2	57
β-strand	1010-1012	3	51
α-helix	1014-1016	3
β-strand	1022	1	46
α-helix	1023-1038	16
β-strand	1042-1043	2	50
α-helix	1052-1061	10
β-strand	1072-1073	2	57
α-helix	1079	1
β-strand	1080	1	57
α-helix	1081	1
β-strand	1086-1094	9	51
β-strand	1095	1	47
α-helix	1099-1101	3
β-strand	1104-1106	3	14
β-strand	1111	1	58
β-strand	1118	1	58
α-helix	1119-1120	2
α-helix	1122-1124	3
α-helix	1127	1
β-strand	1128-1130	3	13
α-helix	1132-1141	10
α-helix	1144-1151	8
β-strand	1158-1163	6	1
β-strand	1174	1	59
β-strand	1179	1	59
β-strand	1182	1	60
β-strand	1187	1	60
β-strand	1191-1196	6	1
α-helix	1198-1209	12
β-strand	1212-1217	6	2

Chain C: 12 helices, 12 β-strands

Element	Residues	Length	Sheet
β-strand	7-13	7	61
β-strand	17-23	7	61
α-helix	27-39	13
β-strand	43-54	12	62
α-helix	60-69	10
β-strand	72	1	63
α-helix	75-79	5
α-helix	83-85	3
β-strand	97-104	8	62
β-strand	111-114	4	64
α-helix	115-117	3
β-strand	119-120	2	62
α-helix	131	1
β-strand	132	1	63
α-helix	133	1
β-strand	143-147	5	64
β-strand	152-162	11	62
α-helix	168-170	3
β-strand	173-180	8	61
α-helix	197-200	4
α-helix	202-204	3
α-helix	205-208	4
β-strand	228-234	7	61
α-helix	240-264	25

Chain D: 8 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	6	1	31
α-helix	17-19	3
β-strand	36-38	3	65
β-strand	44-46	3	65
β-strand	49	1	31
α-helix	54-72	19
α-helix	120-133	14
α-helix	139-151	13
α-helix	157-167	11
α-helix	174-182	9
α-helix	188-194	7
α-helix	204-217	14

Chain E: 12 helices, 14 β-strands

Element	Residues	Length	Sheet
α-helix	3-5	3
α-helix	6-25	20
β-strand	28	1	66
α-helix	32-35	4
α-helix	39-46	8
β-strand	47	1	67
β-strand	53	1	67
α-helix	55-57	3
β-strand	60-62	3	68
β-strand	64	1	66
α-helix	68-71	4
β-strand	78-82	5	68
β-strand	87-88	2	69
α-helix	90-103	14
β-strand	107-112	6	68
β-strand	115-116	2	69
α-helix	120-123	4
β-strand	131-136	6	68
α-helix	137-140	4
α-helix	144-146	3
β-strand	152-156	5	70
α-helix	158-167	10
β-strand	177-178	2	70
α-helix	183-188	6
β-strand	195-200	6	70
β-strand	208-214	7	70

Chain F: 3 helices, 5 β-strands

Element	Residues	Length	Sheet
β-strand	73	1	31
β-strand	84	1	71
α-helix	85-86	2
α-helix	87-102	16
α-helix	117-125	9
β-strand	132-137	6	31
β-strand	143-147	5	31
β-strand	152	1	71

Chain G: 3 helices, 15 β-strands

Element	Residues	Length	Sheet
β-strand	3-13	11	31
α-helix	15-17	3
α-helix	22-33	12
β-strand	37-39	3	31
β-strand	43-49	7	31
β-strand	55	1	31
β-strand	59-61	3	31
α-helix	62	1
β-strand	68-79	12	31
β-strand	86-95	10	72
β-strand	98-103	6	72
β-strand	106-111	6	72
β-strand	121-122	2	73
β-strand	129-132	4	73
β-strand	135-137	3	73
β-strand	142-153	12	72
β-strand	156-162	7	72
β-strand	169-170	2	72

Chain H: 0 helices, 8 β-strands

Element	Residues	Length	Sheet
β-strand	4-16	13	17
β-strand	23-30	8	17
β-strand	37-43	7	17
β-strand	54-60	7	17
β-strand	95-103	9	17
β-strand	112-118	7	17
β-strand	121-127	7	17
β-strand	140-145	6	17

5 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase II subunit RPB1	A	protein	1733	SACCHAROMYCES CEREVISIAE	P04050 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB2	B	protein	1224	SACCHAROMYCES CEREVISIAE	P08518 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB3	C	protein	318	SACCHAROMYCES CEREVISIAE	P16370 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB4	D	protein	221	SACCHAROMYCES CEREVISIAE	P20433 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit rpabc 1	E	protein	215	SACCHAROMYCES CEREVISIAE	P20434
DNA-directed RNA polymerases I, II, and III subunit rpabc 2	F	protein	155	SACCHAROMYCES CEREVISIAE	P20435
DNA-directed RNA polymerase II subunit RPB7	G	protein	171	SACCHAROMYCES CEREVISIAE	P34087
DNA-directed RNA polymerases I, II, and III subunit rpabc 3	H	protein	146	SACCHAROMYCES CEREVISIAE	P20436
DNA-directed RNA polymerase II subunit RPB9	I	protein	122	SACCHAROMYCES CEREVISIAE	P27999
DNA-directed RNA polymerases I, II, and III subunit rpabc 5	J	protein	70	SACCHAROMYCES CEREVISIAE	P22139
DNA-directed RNA polymerase II subunit RPB11	K	protein	120	SACCHAROMYCES CEREVISIAE	P38902
DNA-directed RNA polymerases I, II, and III subunit rpabc 4	L	protein	70	SACCHAROMYCES CEREVISIAE	P40422

4 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>4BBS_1 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGS
IDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNE
LMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLK
LVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLP
VPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHV
ATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLE
LDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKR
AGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNA
DFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTF
IELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSP
KDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHN
GFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVR
FLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFV
DRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRR
LVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVD
LLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNI
RRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCC
LLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMT
LNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEH
TTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRA
AMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHML
KKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVP
GIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGG
LTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGA
FDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGS
NDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTS
PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS
PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR

Sequence of entity 2 (B), FASTA

>4BBS_2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (chains B)
MSDLANSEKYYDEDPYGFEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQ
DIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLR
NLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCY
LSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEI
RSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEH
ICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEF
LPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTL
FKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVS
QVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLS
LMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETL
RTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAK
LMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEEND
LDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGV
FLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMI
MNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIA
PGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDG
LKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSR
MTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKK
LMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIA
HGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAA
KLLFQELMAMNITPRLYTDRSRDF

Sequence of entity 3 (C), FASTA

>4BBS_3 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 (chains C)
MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD
EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI
VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY
DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV
DQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPY
SNASQMGNTGSGGYDNAW

Sequence of entity 4 (D), FASTA

>4BBS_4 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 (chains D)
MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIK
EALVERRRAFKRSQKKHKKKHLKHENANDETTAVEDEDDDLDEDDVNADDDDFMHSETRE
KELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQL
GSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY

Sequence of entity 5 (E), FASTA

>4BBS_5 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>4BBS_6 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>4BBS_7 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 (chains G)
MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGR
ILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLT
FNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI

Sequence of entity 8 (H), FASTA

>4BBS_8 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>4BBS_9 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 (chains I)
MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQ
DIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ
FS

Sequence of entity 10 (J), FASTA

>4BBS_10 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>4BBS_11 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 (chains K)
MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAA
YKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF

Sequence of entity 12 (L), FASTA

>4BBS_12 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	9
MG	Magnesium ion	Mg	2

Primary citation

Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex. Sainsbury, S., Niesser, J., Cramer, P. Nature (2013) 493:437. DOI 10.1038/NATURE11715 · PubMed

Other PDB entries of the same protein (UniProt P04050 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5VKO 1.8 Å, SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493
9SV6 1.96 Å, CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1
5VKL 2.2 Å, SPT6 tSH2-RPB1 1476-1500 pS1493
9W8V 2.23 Å, Structure of post-translocation state of yeast Pol II complexed with a cisplatin-induced…
9QEB 2.26 Å, CryoEM structure of transcribing RNA polymerase II elongation complex
1TWF 2.3 Å, RNA polymerase II complexed with UTP at 2.3 A resolution
9RYB 2.33 Å, CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis…
9KD8 2.46 Å, The structure of RNA polymerase II elongation complex paused at N-2 state by actinomycin…
6NPW 2.49 Å, SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide
9K7F 2.5 Å, RNA polymerase II elongation complex apo structure.
30ES 2.54 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…
30EP 2.55 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…

Browse structure collections

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