4BY7: Elongating RNA Polymerase II-Bye1 TLD complex

elongating RNA Polymerase II-Bye1 TLD complex. Determined by X-ray diffraction at 3.15 Å resolution. Released 11 Sept 2013.

Method: X-ray diffraction
Resolution: 3.15 Å
Organisms: SACCHAROMYCES CEREVISIAE, SYNTHETIC CONSTRUCT
Chains: 16
Atoms: 33,227
Mol. weight: 548.11 kDa
Ligands: ZN, MG
Released: 11 Sept 2013

Explore 4BY7 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4BY7 contains 201 α-helices and 218 β-strands across 13 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 77 helices, 67 β-strands

Element	Residues	Length	Sheet
α-helix	10	1
β-strand	11	1	1
β-strand	16-18	3	2
β-strand	21	1	3
α-helix	24-30	7
β-strand	34	1	4
β-strand	82-91	10	4
α-helix	93-95	3
α-helix	96-103	8
β-strand	106	1	5
β-strand	113	1	5
α-helix	120-126	7
α-helix	131-142	12
β-strand	147	1	6
β-strand	151-153	3	7
β-strand	161-163	3	7
α-helix	169	1
β-strand	170	1	6
α-helix	171-172	2
β-strand	175-177	3	8
β-strand	180-185	6	8
β-strand	198-202	5	8
α-helix	203	1
α-helix	204-212	9
α-helix	216-221	6
β-strand	225	1	9
β-strand	229	1	9
α-helix	231-234	4
β-strand	235-241	7	4
α-helix	244-246	3
α-helix	248-251	4
α-helix	261-281	21
α-helix	289-304	16
α-helix	325-329	5
α-helix	335-340	6
β-strand	343-345	3	10
β-strand	348-355	8	11
β-strand	363-367	5	11
α-helix	368-373	6
β-strand	375-379	5	12
α-helix	385-394	10
β-strand	402-406	5	12
α-helix	411	1
β-strand	412-414	3	12
β-strand	431-435	5	12
α-helix	436	1
β-strand	441-445	5	11
α-helix	452-454	3
β-strand	455-463	9	11
β-strand	468-470	3	11
α-helix	472-474	3
α-helix	475-478	4
β-strand	486-490	5	11
α-helix	495-500	6
α-helix	501-505	5
β-strand	506	1	11
α-helix	507-510	4
β-strand	512-513	2	13
β-strand	518-519	2	13
α-helix	525-534	10
β-strand	540-542	3	14
α-helix	543-552	10
α-helix	560-563	4
β-strand	565	1	14
β-strand	571-573	3	14
α-helix	574-578	5
α-helix	583	1
β-strand	588-589	2	15
β-strand	606-607	2	15
β-strand	612-614	3	15
α-helix	619-622	4
α-helix	629-637	9
α-helix	639-660	22
β-strand	663	1	16
α-helix	666-669	4
α-helix	673-698	26
α-helix	710-736	27
α-helix	742-749	8
α-helix	755-762	8
β-strand	766-767	2	17
β-strand	770	1	18
β-strand	773	1	18
β-strand	779	1	19
β-strand	782	1	19
β-strand	799-800	2	17
α-helix	810-829	20
α-helix	832-845	14
β-strand	849-850	2	20
β-strand	856-857	2	20
β-strand	863-865	3	20
α-helix	868-870	3
β-strand	873	1	21
α-helix	875-877	3
β-strand	878-882	5	22
α-helix	890-897	8
α-helix	908-909	2
β-strand	913	1	23
α-helix	914-916	3
α-helix	923-946	24
β-strand	953-957	5	22
α-helix	960-971	12
α-helix	978	1
β-strand	979	1	23
α-helix	983-994	12
α-helix	1005-1014	10
α-helix	1016-1025	10
α-helix	1028-1029	2
α-helix	1030-1035	6
α-helix	1039-1056	18
β-strand	1057	1	21
α-helix	1058-1059	2
α-helix	1064-1077	14
α-helix	1097-1105	9
β-strand	1115-1119	5	24
β-strand	1120	1	25
α-helix	1128-1138	11
β-strand	1141-1142	2	26
α-helix	1143-1146	4
β-strand	1147-1154	8	27
α-helix	1167-1169	3
α-helix	1170-1174	5
β-strand	1191-1197	7	27
α-helix	1199-1204	6
α-helix	1209-1217	9
β-strand	1224-1228	5	27
β-strand	1236-1242	7	27
α-helix	1258-1269	12
β-strand	1272-1274	3	26
β-strand	1280-1292	13	24
β-strand	1298-1309	12	24
α-helix	1313-1317	5
β-strand	1322	1	25
β-strand	1328-1329	2	24
α-helix	1332-1339	8
α-helix	1341-1358	18
α-helix	1365-1376	12
α-helix	1389-1391	3
α-helix	1396-1400	5
α-helix	1405-1414	10
β-strand	1418-1419	2	2
α-helix	1424-1430	7
α-helix	1437-1439	3
β-strand	1442-1445	4	28
α-helix	1447-1450	4

Chain B: 61 helices, 73 β-strands

Element	Residues	Length	Sheet
α-helix	23	1
β-strand	24	1	29
α-helix	25	1
α-helix	30-41	12
α-helix	45-53	9
α-helix	54-58	5
α-helix	59-62	4
β-strand	92-97	6	30
α-helix	98-100	3
β-strand	101-102	2	31
β-strand	110-111	2	31
α-helix	112-113	2
α-helix	114-119	6
β-strand	125-132	8	30
α-helix	133	1
β-strand	165-171	7	30
α-helix	172-173	2
α-helix	180-182	3
α-helix	186-191	6
β-strand	203-205	3	32
β-strand	208-212	5	32
β-strand	214-218	5	33
α-helix	219	1
β-strand	223-227	5	34
α-helix	228-229	2
β-strand	234-242	9	34
β-strand	252-260	9	34
β-strand	269-272	4	34
α-helix	273	1
α-helix	279	1
β-strand	280-281	2	34
α-helix	282-288	7
α-helix	297-301	5
α-helix	308-312	5
α-helix	315-321	7
α-helix	327-336	10
α-helix	345-354	10
α-helix	355-359	5
α-helix	372-389	18
α-helix	394-396	3
α-helix	401-403	3
β-strand	404-407	4	33
α-helix	409-434	26
α-helix	451-463	13
β-strand	480-482	3	32
α-helix	483-484	2
α-helix	488-494	7
β-strand	497-499	3	33
α-helix	516-518	3
β-strand	522	1	35
β-strand	536-538	3	33
β-strand	539	1	35
β-strand	544-545	2	36
α-helix	552-560	9
β-strand	564-565	2	37
α-helix	577	1
β-strand	578-582	5	37
β-strand	586-590	5	37
α-helix	593-606	14
β-strand	614-618	5	37
β-strand	623-627	5	37
β-strand	633-639	7	36
β-strand	640-641	2	38
β-strand	650-651	2	38
β-strand	654	1	29
α-helix	655-666	12
α-helix	681-686	6
β-strand	690-694	5	36
α-helix	695-698	4
β-strand	703-704	2	36
α-helix	728-729	2
β-strand	740-741	2	36
α-helix	745-748	4
α-helix	753-755	3
α-helix	759-761	3
α-helix	764-773	10
α-helix	774-776	3
β-strand	777	1	39
β-strand	779	1	40
β-strand	793-796	4	40
β-strand	800	1	41
β-strand	804-805	2	42
α-helix	809-812	4
β-strand	821-827	7	43
β-strand	828	1	16
β-strand	838-842	5	43
α-helix	843-847	5
β-strand	853-862	10	40
β-strand	865	1	44
β-strand	871	1	44
β-strand	873-874	2	45
β-strand	898	1	46
α-helix	899-900	2
β-strand	904-905	2	40
β-strand	910-912	3	46
β-strand	914-915	2	45
β-strand	936	1	45
β-strand	939-940	2	46
α-helix	941-942	2
β-strand	947-956	10	40
β-strand	962-972	11	40
β-strand	979-982	4	43
β-strand	987-994	8	43
β-strand	1001	1	43
β-strand	1010-1012	3	43
α-helix	1014-1016	3
α-helix	1023-1038	16
α-helix	1041	1
β-strand	1042-1043	2	42
α-helix	1052-1060	9
β-strand	1069-1073	5	43
α-helix	1079	1
β-strand	1080-1094	15	43
β-strand	1095	1	39
α-helix	1099-1101	3
β-strand	1104-1106	3	11
β-strand	1111	1	47
β-strand	1118	1	47
α-helix	1119	1
α-helix	1122-1124	3
α-helix	1126-1127	2
β-strand	1128-1130	3	10
α-helix	1132-1141	10
α-helix	1144-1151	8
α-helix	1152-1156	5
β-strand	1157-1163	7	1
β-strand	1174	1	48
β-strand	1179	1	48
β-strand	1182	1	49
β-strand	1187	1	49
β-strand	1191-1197	7	1
α-helix	1198-1209	12
β-strand	1212	1	3
β-strand	1215-1217	3	2

Chain C: 12 helices, 14 β-strands

Element	Residues	Length	Sheet
β-strand	8-13	6	50
β-strand	17-22	6	50
α-helix	27-39	13
β-strand	43-54	12	51
α-helix	60-68	9
β-strand	72-74	3	52
α-helix	77-79	3
β-strand	96-104	9	51
α-helix	110	1
β-strand	111-114	4	53
α-helix	115-117	3
β-strand	119-120	2	51
β-strand	129-132	4	52
α-helix	133	1
β-strand	143-147	5	53
β-strand	152-162	11	51
α-helix	168-170	3
β-strand	173	1	54
β-strand	177-180	4	50
α-helix	197-200	4
α-helix	202-204	3
α-helix	205-209	5
α-helix	217-219	3
β-strand	228-233	6	50
β-strand	234	1	54
α-helix	240-266	27

Chain D: 8 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	6	1	28
β-strand	36-38	3	55
β-strand	44-46	3	55
β-strand	48-49	2	28
α-helix	54-73	20
α-helix	122-133	12
α-helix	139-151	13
α-helix	157-167	11
α-helix	174-182	9
α-helix	188-194	7
α-helix	196-200	5
α-helix	204-217	14

Chain E: 13 helices, 14 β-strands

Element	Residues	Length	Sheet
α-helix	2-25	24
β-strand	28	1	56
α-helix	32-35	4
α-helix	39-46	8
β-strand	47	1	57
β-strand	53	1	57
α-helix	55-58	4
β-strand	60-62	3	58
β-strand	64	1	56
α-helix	66-71	6
β-strand	78-82	5	58
β-strand	87-88	2	59
α-helix	90-102	13
β-strand	107-112	6	58
β-strand	115-116	2	59
α-helix	120-126	7
β-strand	131-136	6	58
α-helix	137-140	4
α-helix	144-146	3
β-strand	152-155	4	60
α-helix	156-157	2
α-helix	158-167	10
α-helix	172-174	3
β-strand	177-178	2	60
α-helix	183-187	5
β-strand	195-200	6	60
β-strand	208-214	7	60

Chain F: 4 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	76-78	3
β-strand	84	1	61
α-helix	85-86	2
α-helix	87-102	16
α-helix	117-126	10
β-strand	132-137	6	28
β-strand	143-147	5	28
β-strand	152	1	61

Chain G: 6 helices, 15 β-strands

Element	Residues	Length	Sheet
β-strand	3-13	11	28
α-helix	15-17	3
α-helix	22-34	13
β-strand	38-39	2	28
β-strand	43-48	6	28
α-helix	51-53	3
β-strand	55	1	28
α-helix	58	1
β-strand	59-61	3	28
α-helix	62	1
β-strand	68-79	12	28
β-strand	86-95	10	62
β-strand	98-103	6	62
β-strand	106-111	6	62
α-helix	112-114	3
β-strand	120-122	3	63
β-strand	129-131	3	63
β-strand	136-137	2	63
β-strand	142-151	10	62
β-strand	158-162	5	62
β-strand	169-170	2	62

Chain H: 1 helix, 8 β-strands

Element	Residues	Length	Sheet
β-strand	7-16	10	14
β-strand	23-30	8	14
β-strand	37-43	7	14
β-strand	54-58	5	14
β-strand	95-106	12	14
β-strand	112-118	7	14
β-strand	121-126	6	14
α-helix	130-132	3
β-strand	140-145	6	14

5 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase II subunit RPB1	A	protein	1733	SACCHAROMYCES CEREVISIAE	P04050 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB2	B	protein	1224	SACCHAROMYCES CEREVISIAE	P08518 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB3	C	protein	318	SACCHAROMYCES CEREVISIAE	P16370 (AlphaFold model)
DNA-directed RNA polymerase II subunit RPB4	D	protein	221	SACCHAROMYCES CEREVISIAE	P20433 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit rpabc 1	E	protein	215	SACCHAROMYCES CEREVISIAE	P20434
DNA-directed RNA polymerases I, II, and III subunit rpabc 2	F	protein	155	SACCHAROMYCES CEREVISIAE	P20435
DNA-directed RNA polymerase II subunit RPB7	G	protein	171	SACCHAROMYCES CEREVISIAE	P34087
DNA-directed RNA polymerases I, II, and III subunit rpabc 3	H	protein	146	SACCHAROMYCES CEREVISIAE	P20436
DNA-directed RNA polymerase II subunit RPB9	I	protein	122	SACCHAROMYCES CEREVISIAE	P27999
DNA-directed RNA polymerases I, II, and III subunit rpabc 5	J	protein	70	SACCHAROMYCES CEREVISIAE	P22139
DNA-directed RNA polymerase II subunit RPB11	K	protein	120	SACCHAROMYCES CEREVISIAE	P38902
DNA-directed RNA polymerases I, II, and III subunit rpabc 4	L	protein	70	SACCHAROMYCES CEREVISIAE	P40422

4 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>4BY7_1 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGS
IDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNE
LMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLK
LVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLP
VPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHV
ATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLE
LDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKR
AGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNA
DFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTF
IELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSP
KDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHN
GFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVR
FLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFV
DRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRR
LVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVD
LLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNI
RRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCC
LLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMT
LNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEH
TTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRA
AMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHML
KKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVP
GIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGG
LTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGA
FDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGS
NDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTS
PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS
PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR

Sequence of entity 2 (B), FASTA

>4BY7_2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (chains B)
MSDLANSEKYYDEDPYGFEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQ
DIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLR
NLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCY
LSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEI
RSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEH
ICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEF
LPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTL
FKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVS
QVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLS
LMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETL
RTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAK
LMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEEND
LDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGV
FLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMI
MNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIA
PGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDG
LKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSR
MTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKK
LMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIA
HGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAA
KLLFQELMAMNITPRLYTDRSRDF

Sequence of entity 3 (C), FASTA

>4BY7_3 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 (chains C)
MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD
EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI
VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY
DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV
DQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPY
SNASQMGNTGSGGYDNAW

Sequence of entity 4 (D), FASTA

>4BY7_4 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 (chains D)
MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIK
EALVERRRAFKRSQKKHKKKHLKHENANDETTAVEDEDDDLDEDDVNADDDDFMHSETRE
KELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQL
GSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY

Sequence of entity 5 (E), FASTA

>4BY7_5 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>4BY7_6 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>4BY7_7 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 (chains G)
MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGR
ILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLT
FNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI

Sequence of entity 8 (H), FASTA

>4BY7_8 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSLATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>4BY7_9 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 (chains I)
MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQ
DIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ
FS

Sequence of entity 10 (J), FASTA

>4BY7_10 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>4BY7_11 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 (chains K)
MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAA
YKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF

Sequence of entity 12 (L), FASTA

>4BY7_12 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	8
MG	Magnesium ion	Mg	1

Water and common crystallization additives (EPE) are not listed.

Primary citation

Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Kinkelin, K., Wozniak, G.G., Rothbart, S.B. et al. Proc Natl Acad Sci U S A (2013) 110:15277-15282. DOI 10.1073/pnas.1311010110 · PubMed

Other PDB entries of the same protein (UniProt P04050 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5VKO 1.8 Å, SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493
9SV6 1.96 Å, CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1
5VKL 2.2 Å, SPT6 tSH2-RPB1 1476-1500 pS1493
9W8V 2.23 Å, Structure of post-translocation state of yeast Pol II complexed with a cisplatin-induced…
9QEB 2.26 Å, CryoEM structure of transcribing RNA polymerase II elongation complex
1TWF 2.3 Å, RNA polymerase II complexed with UTP at 2.3 A resolution
9RYB 2.33 Å, CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis…
9KD8 2.46 Å, The structure of RNA polymerase II elongation complex paused at N-2 state by actinomycin…
6NPW 2.49 Å, SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide
9K7F 2.5 Å, RNA polymerase II elongation complex apo structure.
30ES 2.54 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…
30EP 2.55 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…

Browse structure collections

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