4V7O: Proteasome Activator Complex
Proteasome Activator Complex. Determined by X-ray diffraction at 3.0 Å resolution. Released 9 Jul 2014.
- Method
- X-ray diffraction
- Resolution
- 3.0 Å
- Organism
- Saccharomyces cerevisiae
- Chains
- 68
- Atoms
- 158,904
- Mol. weight
- 2258.06 kDa
- Released
- 9 Jul 2014
Explore 4V7O in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
4V7O contains 908 α-helices and 861 β-strands across 68 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain A1: 4 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4003-4007 | 5 | 223 |
| β-strand | 4012-4016 | 5 | 223 |
| β-strand | 4017 | 1 | 224 |
| β-strand | 4020-4022 | 3 | 225 |
| β-strand | 4025-4028 | 4 | 225 |
| β-strand | 4034-4038 | 5 | 226 |
| β-strand | 4041-4047 | 7 | 226 |
| α-helix | 4051-4070 | 20 | |
| α-helix | 4076-4088 | 13 | |
| β-strand | 4099-4107 | 9 | 226 |
| β-strand | 4112-4118 | 7 | 226 |
| β-strand | 4124-4126 | 3 | 226 |
| β-strand | 4129-4132 | 4 | 223 |
| α-helix | 4135-4146 | 12 | |
| α-helix | 4153-4170 | 18 | |
| β-strand | 4173 | 1 | 110 |
| β-strand | 4178 | 1 | 224 |
| β-strand | 4180-4184 | 5 | 223 |
| β-strand | 4187-4191 | 5 | 223 |
Chains A2 and BZ: 6 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 5002-5008 | 7 | 230 |
| β-strand | 5011-5016 | 6 | 230 |
| β-strand | 5020-5022 | 3 | 99 |
| β-strand | 5025-5028 | 4 | 99 |
| β-strand | 5034-5038 | 5 | 231 |
| β-strand | 5041-5044 | 4 | 231 |
| β-strand | 5047 | 1 | 232 |
| α-helix | 5049-5070 | 22 | |
| α-helix | 5073-5075 | 3 | |
| α-helix | 5076-5088 | 13 | |
| β-strand | 5097 | 1 | 232 |
| β-strand | 5098-5105 | 8 | 231 |
| β-strand | 5109-5116 | 8 | 231 |
| β-strand | 5121-5124 | 4 | 231 |
| β-strand | 5126-5130 | 5 | 230 |
| α-helix | 5133-5142 | 10 | |
| α-helix | 5152-5167 | 16 | |
| β-strand | 5168 | 1 | 96 |
| β-strand | 5174-5181 | 8 | 230 |
| β-strand | 5184-5192 | 9 | 230 |
| α-helix | 5193-5204 | 12 | |
Chains A3 and B1: 5 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 6002-6007 | 6 | 7 |
| β-strand | 6012-6017 | 6 | 7 |
| β-strand | 6020-6022 | 3 | 8 |
| β-strand | 6025-6028 | 4 | 8 |
| β-strand | 6034-6036 | 3 | 9 |
| β-strand | 6041-6047 | 7 | 9 |
| α-helix | 6049-6069 | 21 | |
| α-helix | 6077-6090 | 14 | |
| β-strand | 6098-6105 | 8 | 9 |
| β-strand | 6111-6116 | 6 | 9 |
| β-strand | 6122-6125 | 4 | 9 |
| β-strand | 6127-6131 | 5 | 7 |
| α-helix | 6134-6144 | 11 | |
| β-strand | 6151 | 1 | 10 |
| β-strand | 6160 | 1 | 10 |
| α-helix | 6161-6164 | 4 | |
| α-helix | 6168-6185 | 18 | |
| β-strand | 6186 | 1 | 84 |
| β-strand | 6192-6199 | 8 | 7 |
| β-strand | 6202-6209 | 8 | 7 |
Chains A4, AR and B2: 6 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 706-708 | 3 | 18 |
| β-strand | 7003-7007 | 5 | 19 |
| β-strand | 7012-7017 | 6 | 19 |
| β-strand | 7020-7022 | 3 | 18 |
| β-strand | 7025-7028 | 4 | 18 |
| β-strand | 7034-7037 | 4 | 18 |
| β-strand | 7041-7048 | 8 | 18 |
| α-helix | 7049-7067 | 19 | |
| α-helix | 7081-7097 | 17 | |
| β-strand | 7104-7111 | 8 | 18 |
| β-strand | 7117-7123 | 7 | 18 |
| β-strand | 7128-7129 | 2 | 18 |
| β-strand | 7133-7135 | 3 | 19 |
| α-helix | 7139-7147 | 9 | |
| α-helix | 7154-7156 | 3 | |
| α-helix | 7162-7179 | 18 | |
| β-strand | 7180 | 1 | 73 |
| β-strand | 7186-7193 | 8 | 19 |
| β-strand | 7197-7205 | 9 | 19 |
| α-helix | 7212-7216 | 5 | |
Chain A5: 47 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 240-248 | 9 | |
| α-helix | 249-252 | 4 | |
| α-helix | 257-271 | 15 | |
| α-helix | 280-290 | 11 | |
| β-strand | 295 | 1 | 34 |
| β-strand | 298 | 1 | 34 |
| α-helix | 300-306 | 7 | |
| α-helix | 313-320 | 8 | |
| α-helix | 342-354 | 13 | |
| α-helix | 364-366 | 3 | |
| α-helix | 367-374 | 8 | |
| α-helix | 375-377 | 3 | |
| α-helix | 383-393 | 11 | |
| α-helix | 405-407 | 3 | |
| α-helix | 408-414 | 7 | |
| α-helix | 422-443 | 22 | |
| α-helix | 465-477 | 13 | |
| α-helix | 478-482 | 5 | |
| α-helix | 488-496 | 9 | |
| α-helix | 508-522 | 15 | |
| α-helix | 531-552 | 22 | |
| α-helix | 566-567 | 2 | |
| α-helix | 568-586 | 19 | |
| α-helix | 591-606 | 16 | |
| α-helix | 612-627 | 16 | |
| α-helix | 635-646 | 12 | |
| α-helix | 649-652 | 4 | |
| α-helix | 658-660 | 3 | |
| α-helix | 661-671 | 11 | |
| α-helix | 678-693 | 16 | |
| β-strand | 697 | 1 | 35 |
| α-helix | 709-712 | 4 | |
| α-helix | 714-725 | 12 | |
| α-helix | 739-747 | 9 | |
| α-helix | 751-765 | 15 | |
| α-helix | 773-787 | 15 | |
| β-strand | 789 | 1 | 35 |
| α-helix | 791-806 | 16 | |
| α-helix | 819-831 | 13 | |
| α-helix | 833-835 | 3 | |
| α-helix | 836-852 | 17 | |
| α-helix | 869-882 | 14 | |
| α-helix | 886-890 | 5 | |
| α-helix | 893-905 | 13 | |
| α-helix | 910-916 | 7 | |
| α-helix | 919-928 | 10 | |
| β-strand | 931 | 1 | 36 |
| α-helix | 957-960 | 4 | |
| β-strand | 970 | 1 | 36 |
| α-helix | 974-997 | 24 | |
| α-helix | 1009-1023 | 15 | |
| α-helix | 1026-1029 | 4 | |
| α-helix | 1032-1035 | 4 | |
Chain A6: 63 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 1167-1193 | 27 | |
| α-helix | 1199-1211 | 13 | |
| α-helix | 1231-1238 | 8 | |
| α-helix | 1239-1240 | 2 | |
| α-helix | 1249-1266 | 18 | |
| β-strand | 1271 | 1 | 44 |
| α-helix | 1276-1288 | 13 | |
| α-helix | 1293-1307 | 15 | |
| β-strand | 1310 | 1 | 44 |
| α-helix | 1313-1321 | 9 | |
| α-helix | 1323-1330 | 8 | |
| α-helix | 1335-1343 | 9 | |
| α-helix | 1347-1352 | 6 | |
| α-helix | 1353-1355 | 3 | |
| α-helix | 1359-1369 | 11 | |
| α-helix | 1381-1390 | 10 | |
| α-helix | 1404-1406 | 3 | |
| α-helix | 1408-1410 | 3 | |
| α-helix | 1420-1427 | 8 | |
| α-helix | 1430-1451 | 22 | |
| α-helix | 1460-1471 | 12 | |
| α-helix | 1481-1488 | 8 | |
| α-helix | 1489-1493 | 5 | |
| α-helix | 1496-1506 | 11 | |
| α-helix | 1508-1519 | 12 | |
| α-helix | 1523-1526 | 4 | |
| β-strand | 1536-1540 | 5 | 45 |
| α-helix | 1547-1554 | 8 | |
| β-strand | 1563 | 1 | 45 |
| β-strand | 1571 | 1 | 46 |
| β-strand | 1574 | 1 | 46 |
| β-strand | 1578-1582 | 5 | 45 |
| α-helix | 1593-1603 | 11 | |
| α-helix | 1608-1620 | 13 | |
| α-helix | 1630-1642 | 13 | |
| α-helix | 1643-1647 | 5 | |
| α-helix | 1652-1654 | 3 | |
| α-helix | 1655-1661 | 7 | |
| α-helix | 1668-1681 | 14 | |
| α-helix | 1695-1708 | 14 | |
| α-helix | 1716-1730 | 15 | |
| α-helix | 1733-1735 | 3 | |
| α-helix | 1740-1743 | 4 | |
| α-helix | 1764-1774 | 11 | |
| β-strand | 1775 | 1 | 47 |
| β-strand | 1777 | 1 | 47 |
| α-helix | 1782-1787 | 6 | |
| α-helix | 1795-1810 | 16 | |
| β-strand | 1817 | 1 | 46 |
| α-helix | 1820-1828 | 9 | |
| α-helix | 1843-1856 | 14 | |
| α-helix | 1858-1861 | 4 | |
| α-helix | 1875-1890 | 16 | |
| α-helix | 1893-1895 | 3 | |
| α-helix | 1896-1902 | 7 | |
| α-helix | 1903-1907 | 5 | |
| α-helix | 1919-1923 | 5 | |
| α-helix | 1929-1932 | 4 | |
| α-helix | 1933-1935 | 3 | |
| α-helix | 1942-1951 | 10 | |
| α-helix | 1964-1977 | 14 | |
| α-helix | 1986-1989 | 4 | |
| α-helix | 1991-1994 | 4 | |
| α-helix | 2004-2019 | 16 | |
| α-helix | 2024-2034 | 11 | |
| α-helix | 2045-2054 | 10 | |
| α-helix | 2056-2069 | 14 | |
| α-helix | 2081-2090 | 10 | |
| α-helix | 2099-2102 | 4 | |
| α-helix | 2104-2113 | 10 | |
| α-helix | 2118-2121 | 4 | |
| α-helix | 2122-2124 | 3 | |
| α-helix | 2131-2133 | 3 | |
| β-strand | 2142 | 1 | 56 |
Chain A7: 47 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 240-248 | 9 | |
| α-helix | 249-252 | 4 | |
| α-helix | 257-271 | 15 | |
| α-helix | 280-290 | 11 | |
| β-strand | 295 | 1 | 65 |
| β-strand | 298 | 1 | 65 |
| α-helix | 300-306 | 7 | |
| α-helix | 313-320 | 8 | |
| α-helix | 342-354 | 13 | |
| α-helix | 364-366 | 3 | |
| α-helix | 367-374 | 8 | |
| α-helix | 375-377 | 3 | |
| α-helix | 383-393 | 11 | |
| α-helix | 405-407 | 3 | |
| α-helix | 408-414 | 7 | |
| α-helix | 422-443 | 22 | |
| α-helix | 465-477 | 13 | |
| α-helix | 478-482 | 5 | |
| α-helix | 489-496 | 8 | |
| α-helix | 508-522 | 15 | |
| α-helix | 531-552 | 22 | |
| α-helix | 566-567 | 2 | |
| α-helix | 568-585 | 18 | |
| α-helix | 591-606 | 16 | |
| α-helix | 612-627 | 16 | |
| α-helix | 635-646 | 12 | |
| α-helix | 649-652 | 4 | |
| α-helix | 658-660 | 3 | |
| α-helix | 661-671 | 11 | |
| α-helix | 678-693 | 16 | |
| β-strand | 697 | 1 | 66 |
| α-helix | 709-712 | 4 | |
| α-helix | 714-725 | 12 | |
| α-helix | 739-747 | 9 | |
| α-helix | 751-765 | 15 | |
| α-helix | 773-787 | 15 | |
| β-strand | 789 | 1 | 66 |
| α-helix | 791-806 | 16 | |
| α-helix | 819-831 | 13 | |
| α-helix | 833-835 | 3 | |
| α-helix | 836-852 | 17 | |
| α-helix | 869-882 | 14 | |
| α-helix | 886-890 | 5 | |
| α-helix | 893-905 | 13 | |
| α-helix | 910-916 | 7 | |
| α-helix | 919-928 | 10 | |
| β-strand | 931 | 1 | 67 |
| α-helix | 957-960 | 4 | |
| β-strand | 970 | 1 | 67 |
| α-helix | 974-997 | 24 | |
| α-helix | 1009-1023 | 15 | |
| α-helix | 1026-1029 | 4 | |
| α-helix | 1032-1035 | 4 | |
Chain A8: 63 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 1167-1193 | 27 | |
| α-helix | 1199-1211 | 13 | |
| α-helix | 1231-1238 | 8 | |
| α-helix | 1239-1240 | 2 | |
| α-helix | 1249-1266 | 18 | |
| β-strand | 1271 | 1 | 76 |
| α-helix | 1276-1288 | 13 | |
| α-helix | 1293-1307 | 15 | |
| β-strand | 1310 | 1 | 76 |
| α-helix | 1313-1330 | 18 | |
| α-helix | 1335-1343 | 9 | |
| α-helix | 1347-1352 | 6 | |
| α-helix | 1353-1355 | 3 | |
| α-helix | 1357-1369 | 13 | |
| α-helix | 1381-1390 | 10 | |
| α-helix | 1404-1406 | 3 | |
| α-helix | 1408-1410 | 3 | |
| α-helix | 1420-1427 | 8 | |
| α-helix | 1430-1451 | 22 | |
| α-helix | 1461-1471 | 11 | |
| α-helix | 1481-1488 | 8 | |
| α-helix | 1489-1493 | 5 | |
| α-helix | 1496-1506 | 11 | |
| α-helix | 1508-1511 | 4 | |
| α-helix | 1514-1518 | 5 | |
| α-helix | 1523-1526 | 4 | |
| β-strand | 1536-1540 | 5 | 77 |
| α-helix | 1547-1554 | 8 | |
| β-strand | 1563 | 1 | 77 |
| β-strand | 1571 | 1 | 78 |
| β-strand | 1574 | 1 | 78 |
| β-strand | 1578-1582 | 5 | 77 |
| α-helix | 1593-1603 | 11 | |
| α-helix | 1608-1620 | 13 | |
| α-helix | 1630-1642 | 13 | |
| α-helix | 1643-1647 | 5 | |
| α-helix | 1652-1654 | 3 | |
| α-helix | 1655-1661 | 7 | |
| α-helix | 1668-1681 | 14 | |
| α-helix | 1693-1708 | 16 | |
| α-helix | 1716-1730 | 15 | |
| α-helix | 1733-1735 | 3 | |
| α-helix | 1737-1743 | 7 | |
| α-helix | 1764-1774 | 11 | |
| β-strand | 1775 | 1 | 79 |
| β-strand | 1777 | 1 | 79 |
| α-helix | 1782-1787 | 6 | |
| α-helix | 1795-1810 | 16 | |
| β-strand | 1817 | 1 | 78 |
| α-helix | 1820-1828 | 9 | |
| α-helix | 1843-1856 | 14 | |
| α-helix | 1858-1861 | 4 | |
| α-helix | 1868-1870 | 3 | |
| α-helix | 1875-1890 | 16 | |
| α-helix | 1893-1895 | 3 | |
| α-helix | 1896-1902 | 7 | |
| α-helix | 1903-1907 | 5 | |
| α-helix | 1919-1923 | 5 | |
| α-helix | 1929-1934 | 6 | |
| α-helix | 1942-1951 | 10 | |
| α-helix | 1964-1978 | 15 | |
| α-helix | 1986-1989 | 4 | |
| α-helix | 1991-1994 | 4 | |
| α-helix | 2004-2019 | 16 | |
| α-helix | 2024-2034 | 11 | |
| α-helix | 2045-2054 | 10 | |
| α-helix | 2056-2069 | 14 | |
| α-helix | 2081-2090 | 10 | |
| α-helix | 2099-2102 | 4 | |
| α-helix | 2104-2113 | 10 | |
| α-helix | 2118-2121 | 4 | |
| α-helix | 2122-2124 | 3 | |
| α-helix | 2131-2133 | 3 | |
| β-strand | 2142 | 1 | 191 |
43 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Proteasome component C7-alpha | AA, AC, BA, BO | protein | 243 | Saccharomyces cerevisiae | P21243 (AlphaFold model) |
| Proteasome component Y7 | AG, AS, BB, BP | protein | 231 | Saccharomyces cerevisiae | P23639 (AlphaFold model) |
| Proteasome component Y13 | AH, AT, BC, BQ | protein | 232 | Saccharomyces cerevisiae | P23638 (AlphaFold model) |
| Proteasome component PRE6 | AI, AU, BD, BR | protein | 227 | Saccharomyces cerevisiae | P40303 (AlphaFold model) |
| Proteasome component PUP2 | AJ, AV, BE, BS | protein | 250 | Saccharomyces cerevisiae | P32379 |
| Proteasome component PRE5 | AK, AW, BF, BT | protein | 234 | Saccharomyces cerevisiae | P40302 |
| Proteasome component C1 | AL, AX, BG, BU | protein | 244 | Saccharomyces cerevisiae | P21242 |
| Proteasome component PRE3 | AB, AD, BH, BV | protein | 196 | Saccharomyces cerevisiae | P38624 |
| Proteasome component PUP1 | AM, AY, BI, BW | protein | 222 | Saccharomyces cerevisiae | P25043 |
| Proteasome component PUP3 | AN, AZ, BJ, BX | protein | 204 | Saccharomyces cerevisiae | P25451 |
| Proteasome component C11 | A1, AO, BK, BY | protein | 198 | Saccharomyces cerevisiae | P22141 |
| Proteasome component PRE2 | A2, AP, BL, BZ | protein | 212 | Saccharomyces cerevisiae | P30656 |
5 more molecules are not listed.
Sequence of entity 1 (AA, AC, BA, BO), FASTA
>4V7O_1 Proteasome component C7-alpha (chains AA, AC, BA, BO)
AGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTV
SYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYT
QRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKS
KIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIA
EQD
Sequence of entity 2 (AG, AS, BB, BP), FASTA
>4V7O_2 Proteasome component Y7 (chains AG, AS, BB, BP)
QIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKVSLLTPDIGAVYSGMG
PDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGH
DEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKES
VEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEINDRLEAL
Sequence of entity 3 (AH, AT, BC, BQ), FASTA
>4V7O_3 Proteasome component Y13 (chains AH, AT, BC, BQ)
SPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKI
AVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGV
SFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELA
LKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVKTGIT
Sequence of entity 4 (AI, AU, BD, BR), FASTA
>4V7O_4 Proteasome component PRE6 (chains AI, AU, BD, BR)
IFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFS
GLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIA
GFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTV
RSLLEVVQTGAKNIEITVVKPDSDIVALSSEEINQYVTQIEQEKQEQ
Sequence of entity 5 (AJ, AV, BE, BS), FASTA
>4V7O_5 Proteasome component PUP2 (chains AJ, AV, BE, BS)
MFLTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLE
SDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLA
LRFGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQ
AELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELI
KELKEKEAAE
Sequence of entity 6 (AK, AW, BF, BT), FASTA
>4V7O_6 Proteasome component PRE5 (chains AK, AW, BF, BT)
MFRNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQ
KKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNT
QSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFI
KIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI
Sequence of entity 7 (AL, AX, BG, BU), FASTA
>4V7O_7 Proteasome component C1 (chains AL, AX, BG, BU)
GTGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKN
VKIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHT
LYNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHP
EGLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQ
KEIN
Sequence of entity 8 (AB, AD, BH, BV), FASTA
>4V7O_8 Proteasome component PRE3 (chains AB, AD, BH, BV)
ASIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQ
YHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH
KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTA
AGVERLIFYPDEYEQL
Sequence of entity 9 (AM, AY, BI, BW), FASTA
>4V7O_9 Proteasome component PUP1 (chains AM, AY, BI, BW)
TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIG
SNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD
VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEI
GKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICD
Sequence of entity 10 (AN, AZ, BJ, BX), FASTA
>4V7O_10 Proteasome component PUP3 (chains AN, AZ, BJ, BX)
SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVT
TLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALS
GWGAVVYIIKKDEVVKRYLKMRQD
Sequence of entity 11 (A1, AO, BK, BY), FASTA
>4V7O_11 Proteasome component C11 (chains A1, AO, BK, BY)
MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYI
QANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID
YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI
VKIVDKDGIRQVDDFQAQ
Sequence of entity 12 (A2, AP, BL, BZ), FASTA
>4V7O_12 Proteasome component PRE2 (chains A2, AP, BL, BZ)
TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKRVIEINPFLLGTMAGGAADCQFWETWLG
SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT
RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV
TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG
Primary citation
Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening. Sadre-Bazzaz, K., Whitby, F.G., Robinson, H. et al. Mol Cell (2010) 37:728-735. DOI 10.1016/j.molcel.2010.02.002 · PubMed
Other PDB entries of the same protein (UniProt P21243 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 1RYP 1.9 Å, Crystal structure of the 20S proteasome from yeast at 2.4 Å resolution
- 8RVQ 2.02 Å, 20S proteasome from pre1-1
- 4R17 2.1 Å, Ligand-induced aziridine-formation at subunit beta5 of the yeast 20S proteasome
- 8RVL 2.14 Å, Proteasomal late precursor complex from pre1-1
- 8U7U 2.16 Å, Proteasome 20S Core Particle from Beta 3 D205 deletion
- 1G65 2.25 Å, Crystal structure of epoxomicin:20s proteasome reveals a molecular basis for selectivity…
- 8RVP 2.28 Å, Proteasomal late precursor complex from pre1-1, state 2
- 4QVP 2.3 Å, yCP beta5-M45T mutant in complex with bortezomib
- 5CZ4 2.3 Å, Yeast 20S proteasome at 2.3 A resolution
- 6HWE 2.3 Å, Yeast 20S proteasome beta2-G45A mutant in complex with carfilzomib
- 9GBK 2.39 Å, Blm10-20S proteasome complex from pre1-1
- 1G0U 2.4 Å, A gated channel into the proteasome core particle
Browse structure collections
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