5BZ0: IBV papain-like protease PLpro C101S mutant

Crystal structure of IBV papain-like protease PLpro C101S mutant in complex with ubiquitin. Determined by X-ray diffraction at 2.1 Å resolution. Released 15 Jun 2016.

Method
X-ray diffraction
Resolution
2.1 Å
Organisms
Avian infectious bronchitis virus (strain Beaudette), Bos taurus
Chains
2
Atoms
2,854
Mol. weight
43.62 kDa
Ligands
ZN
Released
15 Jun 2016

Explore 5BZ0 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5BZ0 contains 15 α-helices and 24 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 11 helices, 16 β-strands

ElementResiduesLengthSheet
α-helix59-624
α-helix69-7810
β-strand85-8841
β-strand91-9441
α-helix95-962
α-helix101-11212
β-strand11712
α-helix120-12910
α-helix134-14310
β-strand15213
α-helix154-1629
β-strand16512
β-strand173-18084
β-strand183-19084
α-helix191-1955
β-strand196-19944
α-helix204-2085
β-strand209-21354
β-strand220-237184
β-strand242-24544
α-helix246-2472
β-strand252-25764
β-strand26313
β-strand264-26964
β-strand272-27434
α-helix281-2833
β-strand286-300154
Chain B: 4 helices, 8 β-strands
ElementResiduesLengthSheet
β-strand2-655
β-strand12-1655
β-strand2216
α-helix23-3412
α-helix38-403
β-strand41-4555
β-strand48-4925
α-helix501
β-strand5516
α-helix57-593
β-strand66-7165
β-strand7513

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Replicase polyprotein 1abAprotein313Avian infectious bronchitis virus (strain Beaudette)P0C6Y1 (AlphaFold model)
Ubiquitin-40S ribosomal protein S27aBprotein76Bos taurusP62992 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>5BZ0_1 Replicase polyprotein 1ab (chains A)
LGSTCKQKTIYLTEDGVKYRSIVLKPGDSLGQFGQVYAKNKIVFTADDVEDKEILYVPTT
DKSILEYYGLDAQKYVIYLQTLAQKWNVQYRDNFLILEWRDGNSWISSAIVLLQAAKIRF
KGFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLKKR
VSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLLLFA
TDGPATVDCDEDAVGTVVFVGSTNSGHCYTQAAGQAFDNLAKDRKFGKKSPYITAMYTRF
AFKNETSLPVAKQ
Sequence of entity 2 (B), FASTA
>5BZ0_2 Ubiquitin-40S ribosomal protein S27a (chains B)
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
IQKESTLHLVLRLRGG

Ligands and cofactors

IDNameFormulaCopies
ZNZinc ionZn1

Primary citation

Crystal structure of IBV papain-like protease PLpro C101S mutant in complex with ubiquitin. Kong, L.Y., Yan, L.M., Zhang, Y. et al. To be published.

Other PDB entries of the same protein (UniProt P0C6Y1 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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