5DAE: AAEL006007-pa

Kazal type inhibitor from salivary glands of Aedes aegypti mosquito. Determined by X-ray diffraction at 1.4 Å resolution. Released 7 Sept 2016.

Method
X-ray diffraction
Resolution
1.4 Å
Organism
Aedes aegypti
Chains
2
Atoms
927
Mol. weight
14.72 kDa
Released
7 Sept 2016

Explore 5DAE in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5DAE contains 7 α-helices and 6 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 3 β-strands

ElementResiduesLengthSheet
β-strand14-1631
β-strand21-2221
α-helix25-328
α-helix35-384
β-strand44-4631
α-helix50-523
Chain B: 4 helices, 3 β-strands
ElementResiduesLengthSheet
α-helix3-53
β-strand14-1632
β-strand21-2222
α-helix25-328
α-helix35-395
β-strand44-4632
α-helix51-533

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
AAEL006007-paA, Bprotein65Aedes aegyptiQ177W0 (AlphaFold model)
Sequence of entity 1 (A, B), FASTA
>5DAE_1 AAEL006007-PA (chains A, B)
ERGVCACPRIYMPVCGSNLKTYNNDCLLRCEINSDLGRANNLRKIADQACDNLTDNVNDF
IPQEY

Primary citation

High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti. Torquato, R.J.S., Lu, S., Martins, N.H. et al. Acta Crystallogr F Struct Biol Commun (2017) 73:469-475. DOI 10.1107/S2053230X17010007 · PubMed

Other PDB entries of the same protein (UniProt Q177W0 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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