Myelin-associated glycoprotein (MAG) deglycosylated full extracellular domain with co-purified ligand. Determined by X-ray diffraction at 3.8 Å resolution. Released 14 Dec 2016.
Explore 5LF5 in 3D Show helices and sheets RCSB PDB PDBe
5LF5 contains 9 α-helices and 48 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 23-25 | 3 | 1 |
| β-strand | 29-33 | 5 | 2 |
| β-strand | 38-40 | 3 | 3 |
| β-strand | 43-45 | 3 | 1 |
| β-strand | 56-61 | 6 | 2 |
| α-helix | 69-71 | 3 | |
| β-strand | 72-75 | 4 | 2 |
| β-strand | 89-91 | 3 | 3 |
| α-helix | 95-97 | 3 | |
| β-strand | 102-104 | 3 | 3 |
| α-helix | 109-111 | 3 | |
| β-strand | 113-120 | 8 | 2 |
| β-strand | 126-128 | 3 | 2 |
| β-strand | 133-138 | 6 | 2 |
| β-strand | 142-144 | 3 | 4 |
| β-strand | 149-150 | 2 | 5 |
| β-strand | 155-162 | 8 | 4 |
| β-strand | 171-175 | 5 | 6 |
| α-helix | 181-182 | 2 | |
| β-strand | 183-191 | 9 | 4 |
| β-strand | 195-204 | 10 | 4 |
| α-helix | 208-210 | 3 | |
| β-strand | 214-220 | 7 | 6 |
| β-strand | 227-233 | 7 | 6 |
| β-strand | 236-237 | 2 | 5 |
| β-strand | 241-245 | 5 | 7 |
| β-strand | 249-252 | 4 | 8 |
| β-strand | 256-264 | 9 | 7 |
| α-helix | 268-269 | 2 | |
| β-strand | 270-274 | 5 | 8 |
| β-strand | 275 | 1 | 9 |
| β-strand | 278 | 1 | 9 |
| β-strand | 282-283 | 2 | 8 |
| β-strand | 287-293 | 7 | 7 |
| β-strand | 301-309 | 9 | 8 |
| β-strand | 312-323 | 12 | 8 |
| α-helix | 325-329 | 5 | |
| β-strand | 330-333 | 4 | 10 |
| β-strand | 336-338 | 3 | 11 |
| β-strand | 343-348 | 6 | 10 |
| β-strand | 357-361 | 5 | 12 |
| β-strand | 364-369 | 6 | 12 |
| β-strand | 374-379 | 6 | 10 |
| α-helix | 384-386 | 3 | |
| β-strand | 388-394 | 7 | 12 |
| β-strand | 401-407 | 7 | 12 |
| β-strand | 408-410 | 3 | 11 |
| β-strand | 414-415 | 2 | 13 |
| β-strand | 420-423 | 4 | 13 |
| β-strand | 428-435 | 8 | 13 |
| β-strand | 441-445 | 5 | 14 |
| β-strand | 460-466 | 7 | 13 |
| β-strand | 469-476 | 8 | 13 |
| α-helix | 483-485 | 3 | |
| β-strand | 487-491 | 5 | 14 |
| β-strand | 496-500 | 5 | 14 |
| β-strand | 503 | 1 | 13 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Myelin-associated glycoprotein | A | protein | 500 | Mus musculus | P20917 (AlphaFold model) |
>5LF5_1 Myelin-associated glycoprotein (chains A) GSGHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSR TQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDI VNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWV QVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHV SLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRT VELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESQLQL ELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESHCAAARDTVQCLCVVKSN PEPSVAFELPSRNVTVNETEREFVYSERSGLLLTSILTIRGQAQAPPRVICTSRNLYGTQ SLELPFQGAHRAAAHHHHHH
| ID | Name | Formula | Copies |
|---|---|---|---|
| MAN | alpha-D-mannopyranose | C6 H12 O6 | 1 |
| NAG | 2-acetamido-2-deoxy-beta-D-glucopyranose | C8 H15 N O6 | 4 |
Structural basis of myelin-associated glycoprotein adhesion and signalling. Pronker, M.F., Lemstra, S., Snijder, J. et al. Nat Commun (2016) 7:13584-13584. DOI 10.1038/ncomms13584 · PubMed
Other PDB entries of the same protein (UniProt P20917 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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