Crystal Structure of Factor VIIa in complex with phenylmethanamine;hydrochloride. Determined by X-ray diffraction at 1.55 Å resolution. Released 21 Jun 2017.
Explore 5PA9 in 3D Show helices and sheets RCSB PDB PDBe
5PA9 contains 14 α-helices and 27 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 154-157 | 4 | |
| β-strand | 161-165 | 5 | 1 |
| β-strand | 169-173 | 5 | 1 |
| β-strand | 178-180 | 3 | 2 |
| β-strand | 187-189 | 3 | 2 |
| α-helix | 199-204 | 6 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 214 | 1 | 3 |
| β-strand | 217-218 | 2 | 4 |
| β-strand | 227-232 | 6 | 5 |
| β-strand | 235-242 | 8 | 5 |
| β-strand | 247-250 | 4 | 5 |
| α-helix | 252-255 | 4 | |
| α-helix | 261-263 | 3 | |
| β-strand | 264-268 | 5 | 5 |
| β-strand | 272 | 1 | 6 |
| β-strand | 281-291 | 11 | 5 |
| β-strand | 304-308 | 5 | 5 |
| α-helix | 311-314 | 4 | |
| β-strand | 315 | 1 | 7 |
| β-strand | 318 | 1 | 7 |
| α-helix | 320-321 | 2 | |
| β-strand | 322 | 1 | 4 |
| α-helix | 326-331 | 6 | |
| α-helix | 333-335 | 3 | |
| β-strand | 338-343 | 6 | 4 |
| β-strand | 346 | 1 | 8 |
| α-helix | 352 | 1 | |
| β-strand | 353 | 1 | 8 |
| α-helix | 354 | 1 | |
| β-strand | 356 | 1 | 6 |
| β-strand | 358-365 | 8 | 4 |
| α-helix | 367-373 | 7 | |
| β-strand | 387-390 | 4 | 4 |
| β-strand | 398 | 1 | 3 |
| β-strand | 407-412 | 6 | 4 |
| β-strand | 415-424 | 10 | 4 |
| β-strand | 435-439 | 5 | 4 |
| α-helix | 440-443 | 4 | |
| α-helix | 444-451 | 8 | |
| α-helix | 454-455 | 2 | |
| β-strand | 460-463 | 4 | 5 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Coagulation factor VII light chain | A | protein | 64 | Homo sapiens | P08709 (AlphaFold model) |
| Coagulation factor VII heavy chain | C | protein | 254 | Homo sapiens | P08709 (AlphaFold model) |
>5PA9_1 Coagulation factor VII light chain (chains A) LICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASK PQGR
>5PA9_2 Coagulation factor VII heavy chain (chains C) IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGY SDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMR SEPRPGVLLRAPFP
Water and common crystallization additives (GOL, CL, SO4) are not listed.
Crystal Structure of a Factor VIIa complex. Mayweg, A., Roever, S., Rudolph, M.G. To be published.
Other PDB entries of the same protein (UniProt P08709 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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