PanDDA analysis group deposition -- Partial occupancy interpretation of PanDDA event map: SETDB1 in complex with FMOMB000017a. Determined by X-ray diffraction at 1.58 Å resolution. Released 21 Aug 2019.
Explore 5QT1 in 3D Show helices and sheets RCSB PDB PDBe
5QT1 contains 6 α-helices and 19 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 191-192 | 2 | 1 |
| β-strand | 194-195 | 2 | 2 |
| β-strand | 198-199 | 2 | 2 |
| β-strand | 203-207 | 5 | 1 |
| β-strand | 213-224 | 12 | 1 |
| β-strand | 227-234 | 8 | 1 |
| β-strand | 239-242 | 4 | 1 |
| α-helix | 244-246 | 3 | |
| β-strand | 247-248 | 2 | 1 |
| α-helix | 252-254 | 3 | |
| α-helix | 255-257 | 3 | |
| β-strand | 263-270 | 8 | 3 |
| β-strand | 273-283 | 11 | 3 |
| β-strand | 293-297 | 5 | 3 |
| β-strand | 302-305 | 4 | 3 |
| α-helix | 307-309 | 3 | |
| β-strand | 310-312 | 3 | 3 |
| β-strand | 313 | 1 | 1 |
| α-helix | 320-323 | 4 | |
| α-helix | 327-339 | 13 | |
| β-strand | 353-358 | 6 | 4 |
| β-strand | 361-371 | 11 | 4 |
| β-strand | 374-379 | 6 | 4 |
| β-strand | 384-389 | 6 | 4 |
| β-strand | 395 | 1 | 4 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Histone-lysine N-methyltransferase SETDB1 | A | protein | 225 | Homo sapiens | Q15047 (AlphaFold model) |
>5QT1_1 Histone-lysine N-methyltransferase SETDB1 (chains A) MHHHHHHSSGRENLYFQGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKG KSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFD DGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEW EGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKT
| ID | Name | Formula | Copies |
|---|---|---|---|
| DSJ | 1-(4-amino-2-hydroxyphenyl)ethan-1-one | C8 H9 N O2 | 1 |
Water and common crystallization additives (DMS, EDO, UNX, SO4) are not listed.
PanDDA analysis group deposition. Harding, R.J., Tempel, W., DOUANGAMATH, A. et al. To be published.
Other PDB entries of the same protein (UniProt Q15047 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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