5W94: Scc4

Crystal structure of Scc4 in complex with Scc2n and Ctf19n. Determined by X-ray diffraction at 3.19 Å resolution. Released 4 Oct 2017.

Method
X-ray diffraction
Resolution
3.19 Å
Organism
Saccharomyces cerevisiae
Chains
6
Atoms
11,738
Mol. weight
185.82 kDa
Released
4 Oct 2017

Explore 5W94 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5W94 contains 71 α-helices and 16 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 33 helices, 4 β-strands

ElementResiduesLengthSheet
β-strand8-921
α-helix10-2718
α-helix28-303
α-helix34-5623
α-helix62-7918
β-strand8012
α-helix83-9715
α-helix107-1159
α-helix116-1205
α-helix121-1255
α-helix128-14518
α-helix151-17020
α-helix174-18714
α-helix1891
α-helix193-20917
α-helix215-2228
α-helix226-24722
α-helix253-27119
β-strand278-28363
β-strand286-29163
α-helix293-2964
α-helix298-31215
α-helix321-34121
α-helix350-37930
α-helix396-40712
α-helix413-4219
α-helix427-44721
α-helix453-47220
α-helix475-4784
α-helix480-49415
α-helix502-5043
α-helix507-52418
α-helix543-55715
α-helix563-57412
α-helix575-5773
α-helix582-59817
α-helix602-61918
Chain B: 3 helices, 4 β-strands
ElementResiduesLengthSheet
α-helix14-174
α-helix32-376
β-strand41-4333
β-strand59-6021
β-strand86-8722
α-helix112-1209
β-strand129-13022
Chain C: 33 helices, 4 β-strands
ElementResiduesLengthSheet
β-strand8-924
α-helix10-2415
α-helix28-303
α-helix34-5623
α-helix62-7918
β-strand8015
α-helix83-10018
α-helix101-1033
α-helix107-1159
α-helix116-1205
α-helix121-1255
α-helix128-14518
α-helix151-17121
α-helix174-18613
α-helix1891
α-helix193-20917
α-helix215-2228
α-helix226-24823
α-helix253-27220
β-strand278-28366
β-strand286-29166
α-helix293-2964
α-helix298-31215
α-helix321-34121
α-helix350-37930
α-helix396-40712
α-helix413-4219
α-helix427-44721
α-helix453-47220
α-helix475-4784
α-helix480-49415
α-helix502-5043
α-helix507-52418
α-helix543-55715
α-helix563-57412
α-helix582-59817
α-helix602-61918
Chain D: 2 helices, 4 β-strands
ElementResiduesLengthSheet
α-helix14-174
β-strand41-4336
β-strand59-6024
β-strand85-8735
α-helix112-1209
β-strand128-13035

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
MAU2 chromatid cohesion factor homologA, Cprotein624Saccharomyces cerevisiaeP40090 (AlphaFold model)
Sister chromatid cohesion protein 2B, Dprotein184Saccharomyces cerevisiaeQ04002 (AlphaFold model)
Ctf19nE, Hprotein6Saccharomyces cerevisiaeQ02732 (AlphaFold model)
Sequence of entity 1 (A, C), FASTA
>5W94_1 MAU2 chromatid cohesion factor homolog (chains A, C)
MENLGDKLSISQVYHLAQEYRDHAYSIANKIGSEEGLKQYYGLMNMSIQMFQLLKTKCTL
SVLEDSKVTFEMVELLIQETYNFDLAELYISSLKERLQTHQSDTDLVEEIMRCEFLLLHD
LPLMRDSKFHYKIALRNCNELVQYMVNLQDELYQNWASVFQYVGVMLCIKLKQHRRVKTS
FHGLLSQCREKSQWKWFLNLCYVNYLLNERFPIPEDALQELRSTELHTVGPELYAWKLAL
EMVIQLCKDGNITDHLNEFKNFFDTNKQSLVTNEGKGCVIKIMPRIALKVELPMIFHYKE
LKNILLLLQSVSYIVNCYDEKGNFSRKFLPKVYSTTQKLIKNIAAGGVSMNELDSRIQTY
KSILEFCEFYKVWEQTLLKGAVVTTESPKLGPSPGYVRLLQAMKVQFEGGGAVEEYTRLA
QSGGTSSEVKMISLLNCYTVQAARVSRCSGDKQGELVEQCNKVWLQVEKLLQETDLQFNP
IWECTVTILWLFSHFEPFSWNPLPCSDKQRAEYVSKLREFYSSNKFVAGEAVADNRFKLK
KALLLQILVNYLGGRMLEHDLGEIYAISAKCFDMCRQQGGMRKVQYVIGIWHLMNCTVAM
RGKDVALTNAKLEALVKQITSVKQ
Sequence of entity 2 (B, D), FASTA
>5W94_2 Sister chromatid cohesion protein 2 (chains B, D)
SNAMSYPGKDKNIPGRIIEALEDLPLSYLVPKDGLAALVNAPMRVSLPFDKTIFTSADDG
RDVNINVLGTANSTTSSIKNEAEKERLVFKRPSNFTSSANSVDYVPTNFLEGLSPLAQSV
LSTHKGLNDSINIEKKSEIVSRPEAKHKLESVTSNAGNLSFNDNSSNKKTKTSTGVTMTQ
ANLA
Sequence of entity 3 (E, H), FASTA
>5W94_3 Ctf19n (chains E, H)
MDFTSD

Primary citation

The Kinetochore Receptor for the Cohesin Loading Complex. Hinshaw, S.M., Makrantoni, V., Harrison, S.C. et al. Cell (2017) 171:72-84.e13. DOI 10.1016/j.cell.2017.08.017 · PubMed

Other PDB entries of the same protein (UniProt P40090 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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