6C48: B-Myb-LIN9-LIN52 complex

Crystal structure of B-Myb-LIN9-LIN52 complex. Determined by X-ray diffraction at 2.32 Å resolution. Released 19 Sept 2018.

Method
X-ray diffraction
Resolution
2.32 Å
Organism
Homo sapiens
Chains
6
Atoms
2,825
Mol. weight
51.14 kDa
Released
19 Sept 2018

Explore 6C48 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6C48 contains 16 α-helices and 4 β-strands across 6 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 2 β-strands

ElementResiduesLengthSheet
β-strand350-35121
β-strand354-35521
α-helix356-39136
α-helix394-3974
α-helix398-42831
Chain B: 3 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix64-7310
α-helix77-10630
α-helix112-1143
Chains C and F: 2 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix663-6675
α-helix672-68514
Chain D: 3 helices, 2 β-strands
ElementResiduesLengthSheet
β-strand350-35122
β-strand354-35522
α-helix356-39136
α-helix394-3974
α-helix398-43235
Chain E: 3 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix65-739
α-helix77-10630
α-helix112-1143

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Protein lin-9 homologA, Dprotein119Homo sapiensQ5TKA1 (AlphaFold model)
Myb-related protein BC, Fprotein32Homo sapiensP10244 (AlphaFold model)
Protein lin-52 homologB, Eprotein68Homo sapiensQ52LA3 (AlphaFold model)
Sequence of entity 1 (A, D), FASTA
>6C48_1 Protein lin-9 homolog (chains A, D)
METLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATI
VLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSST
Sequence of entity 2 (C, F), FASTA
>6C48_2 Myb-related protein B (chains C, F)
APMSSAWKTVACGGTRDQLFMQEKARQLLGRL
Sequence of entity 3 (B, E), FASTA
>6C48_3 Protein lin-52 homolog (chains B, E)
GEFSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFL
NILEKPKK

Primary citation

Structural mechanism of Myb-MuvB assembly. Guiley, K.Z., Iness, A.N., Saini, S. et al. Proc Natl Acad Sci U S A (2018) 115:10016-10021. DOI 10.1073/pnas.1808136115 · PubMed

Other PDB entries of the same protein (UniProt Q5TKA1 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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