6HTS: Human INO80 complex

Cryo-EM structure of the human INO80 complex bound to nucleosome. Determined by electron microscopy at 4.8 Å resolution. Released 7 Nov 2018.

Method: Electron microscopy
Resolution: 4.8 Å
Organisms: Homo sapiens, synthetic construct
Chains: 19
Atoms: 38,744
Mol. weight: 811.32 kDa
Ligands: ZN, ADP
Released: 7 Nov 2018

Explore 6HTS in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6HTS contains 239 α-helices and 208 β-strands across 17 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 27 helices, 27 β-strands

Element	Residues	Length	Sheet
α-helix	13-14	2
β-strand	15	1	1
β-strand	26	1	2
α-helix	31	1
β-strand	32	1	2
α-helix	33	1
β-strand	35-36	2	3
β-strand	39-40	2	3
α-helix	43-58	16
β-strand	61	1	4
β-strand	65-69	5	5
α-helix	76-87	12
β-strand	93-97	5	5
α-helix	108-119	12
β-strand	121-134	14	6
β-strand	138-140	3	6
β-strand	157-163	7	6
β-strand	166-172	7	6
α-helix	174-182	9
β-strand	189-194	6	6
β-strand	200-206	7	6
α-helix	207-211	5
β-strand	215	1	7
β-strand	220-221	2	6
α-helix	222-225	4
β-strand	229-239	11	6
α-helix	240-248	9
α-helix	260-262	3
α-helix	265-266	2
α-helix	270-272	3
α-helix	273-289	17
β-strand	292-295	4	6
β-strand	298-302	5	5
α-helix	304-306	3
α-helix	309-320	12
α-helix	324-325	2
β-strand	326-331	6	5
β-strand	333	1	8
β-strand	336-337	2	9
α-helix	338	1
β-strand	345-346	2	9
α-helix	347-349	3
α-helix	352-357	6
β-strand	359-362	4	5
α-helix	365-367	3
α-helix	368-382	15
β-strand	386	1	10
α-helix	388-400	13
α-helix	403-408	6
α-helix	410-420	11
β-strand	425	1	10
α-helix	427-436	10
β-strand	438	1	11
α-helix	440-450	11

Chain B: 18 helices, 22 β-strands

Element	Residues	Length	Sheet
β-strand	22	1	12
β-strand	42-43	2	13
β-strand	46-47	2	13
α-helix	50-65	16
β-strand	68	1	1
β-strand	72-77	6	11
α-helix	83-94	12
β-strand	100-104	5	11
α-helix	115-126	12
β-strand	128-148	21	7
β-strand	158-164	7	7
β-strand	169-174	6	7
α-helix	176-184	9
β-strand	191-196	6	7
β-strand	202-207	6	7
α-helix	226-228	3
β-strand	233-243	11	7
α-helix	244-252	9
α-helix	256-262	7
α-helix	270-286	17
β-strand	290-292	3	7
β-strand	295-299	5	11
β-strand	305	1	14
α-helix	306-317	12
β-strand	323-328	6	11
β-strand	333-334	2	15
α-helix	335	1
β-strand	336	1	14
β-strand	341-342	2	15
α-helix	343-345	3
α-helix	348-351	4
β-strand	355-359	5	11
α-helix	360-363	4
α-helix	364-378	15
α-helix	384-396	13
α-helix	399-416	18
α-helix	423-432	10
β-strand	434	1	16
α-helix	436-445	10
β-strand	451	1	17

Chain C: 26 helices, 28 β-strands

Element	Residues	Length	Sheet
α-helix	13-14	2
β-strand	15	1	18
β-strand	26	1	19
α-helix	31	1
β-strand	32	1	19
α-helix	33	1
β-strand	35-36	2	20
β-strand	39-40	2	20
α-helix	43-58	16
β-strand	61	1	12
β-strand	65-69	5	16
α-helix	76-87	12
β-strand	93-97	5	16
α-helix	108-119	12
β-strand	121-140	20	21
β-strand	143	1	22
β-strand	153	1	22
β-strand	157-162	6	21
β-strand	167-172	6	21
α-helix	174-182	9
β-strand	189-194	6	21
β-strand	200-206	7	21
α-helix	207-211	5
β-strand	215	1	23
β-strand	220-221	2	21
α-helix	222-224	3
β-strand	229-239	11	21
α-helix	240-248	9
α-helix	256-263	8
α-helix	270-272	3
α-helix	273-289	17
β-strand	292-295	4	21
β-strand	298-302	5	16
α-helix	304-306	3
α-helix	309-320	12
α-helix	324-325	2
β-strand	326-331	6	16
β-strand	333	1	17
β-strand	336-337	2	24
α-helix	338	1
β-strand	345-346	2	24
α-helix	347-349	3
α-helix	352-357	6
β-strand	359-362	4	16
α-helix	365-367	3
α-helix	368-381	14
β-strand	386	1	25
α-helix	388-400	13
α-helix	403-408	6
α-helix	410-420	11
β-strand	425	1	25
α-helix	427-436	10
β-strand	438	1	26
α-helix	440-449	10

Chain D: 22 helices, 22 β-strands

Element	Residues	Length	Sheet
β-strand	22	1	27
β-strand	33	1	28
α-helix	38	1
β-strand	39	1	28
α-helix	40	1
β-strand	42-43	2	29
β-strand	46-47	2	29
α-helix	50-65	16
β-strand	68	1	18
β-strand	72-77	6	26
α-helix	83-93	11
β-strand	100-104	5	26
α-helix	115-126	12
β-strand	128-149	22	23
β-strand	158-164	7	23
β-strand	169-174	6	23
α-helix	176-184	9
β-strand	191-196	6	23
β-strand	202-207	6	23
α-helix	226-228	3
β-strand	233-243	11	23
α-helix	244-252	9
α-helix	257-262	6
α-helix	270-286	17
β-strand	289-292	4	23
β-strand	295-299	5	26
α-helix	301-303	3
α-helix	306-315	10
α-helix	321-323	3
β-strand	324-328	5	26
β-strand	333-334	2	30
α-helix	335	1
β-strand	341-342	2	30
α-helix	343-345	3
α-helix	348-353	6
β-strand	355-359	5	26
α-helix	360-362	3
α-helix	364-377	14
α-helix	386-396	11
α-helix	399-415	17
α-helix	423-432	10
β-strand	434	1	31
α-helix	436-445	10
β-strand	451	1	32

Chain E: 28 helices, 29 β-strands

Element	Residues	Length	Sheet
α-helix	13-14	2
β-strand	15	1	33
β-strand	26	1	34
α-helix	31	1
β-strand	32	1	34
α-helix	33	1
β-strand	35-36	2	35
β-strand	39-40	2	35
α-helix	43-58	16
β-strand	61	1	27
β-strand	65-69	5	31
α-helix	76-87	12
β-strand	93-97	5	31
α-helix	98-101	4
α-helix	108-119	12
β-strand	121-133	13	36
β-strand	134	1	37
β-strand	137-139	3	37
β-strand	152-154	3	23
β-strand	157-162	6	37
β-strand	167-172	6	37
α-helix	175-182	8
β-strand	189-194	6	36
β-strand	200-206	7	36
α-helix	207-211	5
β-strand	215	1	38
β-strand	220-221	2	36
α-helix	222-225	4
β-strand	229-239	11	36
α-helix	240-248	9
α-helix	256-263	8
α-helix	265-266	2
α-helix	270-272	3
α-helix	273-289	17
β-strand	292-295	4	36
β-strand	298-302	5	31
α-helix	304-306	3
α-helix	309-319	11
α-helix	324-325	2
β-strand	326-331	6	31
β-strand	333	1	32
β-strand	336-337	2	39
α-helix	338	1
β-strand	345-346	2	39
α-helix	347-349	3
α-helix	352-357	6
β-strand	359-362	4	31
α-helix	365-367	3
α-helix	368-382	15
β-strand	386	1	40
α-helix	388-400	13
α-helix	403-408	6
α-helix	410-420	11
β-strand	425	1	40
α-helix	427-436	10
β-strand	438	1	41
α-helix	440-449	10

Chain F: 18 helices, 21 β-strands

Element	Residues	Length	Sheet
β-strand	22	1	4
β-strand	42-43	2	42
β-strand	46-47	2	42
α-helix	50-65	16
β-strand	68	1	33
β-strand	72-76	5	41
α-helix	83-94	12
β-strand	100-104	5	41
α-helix	115-125	11
β-strand	128-148	21	38
β-strand	158-164	7	38
β-strand	169-174	6	38
α-helix	176-184	9
β-strand	191-195	5	38
β-strand	202-207	6	38
α-helix	209-212	4
β-strand	224	1	38
α-helix	226-228	3
β-strand	233-243	11	38
α-helix	244-252	9
α-helix	256-262	7
α-helix	270-286	17
β-strand	290-292	3	38
β-strand	295-299	5	41
α-helix	306-317	12
β-strand	323-327	5	41
β-strand	332	1	43
α-helix	334-335	2
β-strand	343	1	43
α-helix	348-351	4
β-strand	354-358	5	41
α-helix	361-363	3
α-helix	364-378	15
α-helix	386-396	11
α-helix	399-415	17
α-helix	423-432	10
β-strand	434	1	5
α-helix	436-445	10
β-strand	451	1	8

Chain G: 35 helices, 24 β-strands

Element	Residues	Length	Sheet
α-helix	520-534	15
β-strand	539-541	3	44
α-helix	545-547	3
α-helix	549-557	9
β-strand	570-573	4	44
α-helix	579-589	11
β-strand	595	1	44
β-strand	598	1	44
α-helix	602-612	11
β-strand	626-629	4	44
α-helix	631-636	6
α-helix	638-641	4
β-strand	648-652	5	44
α-helix	654-657	4
α-helix	663-670	8
β-strand	675-679	5	44
α-helix	688-698	11
α-helix	728-739	12
β-strand	743-744	2	44
α-helix	756-757	2
β-strand	760-765	6	45
α-helix	769-778	10
α-helix	810-815	6
β-strand	828	1	46
β-strand	831-833	3	47
α-helix	835-837	3
β-strand	838-839	2	48
α-helix	842-846	5
α-helix	855-863	9
α-helix	869-877	9
α-helix	889-893	5
α-helix	898-907	10
α-helix	909-930	22
α-helix	936-937	2
α-helix	938-941	4
α-helix	959-964	6
α-helix	966-971	6
β-strand	989-990	2	49
β-strand	996-997	2	49
β-strand	1017-1019	3	47
α-helix	1020-1022	3
β-strand	1024-1025	2	48
α-helix	1030-1039	10
α-helix	1044-1051	8
α-helix	1055-1064	10
β-strand	1089	1	46
α-helix	1101-1116	16
β-strand	1120-1123	4	45
α-helix	1127-1138	12
β-strand	1143	1	50
β-strand	1146	1	45
α-helix	1153-1161	9
β-strand	1169	1	50
β-strand	1171-1174	4	45
α-helix	1176-1179	4
β-strand	1190-1193	4	45
α-helix	1202-1208	7
β-strand	1220-1226	7	45
α-helix	1231-1247	17

Chain H: 20 helices, 16 β-strands

Element	Residues	Length	Sheet
β-strand	33-37	5	51
β-strand	41-45	5	51
β-strand	59-62	4	51
β-strand	98-99	2	52
β-strand	102-103	2	52
α-helix	106-120	15
β-strand	132-135	4	51
α-helix	142-151	10
α-helix	152-156	5
β-strand	161-164	4	51
α-helix	166-174	9
β-strand	183-188	6	53
β-strand	193-199	7	53
β-strand	202-203	2	53
β-strand	209-211	3	53
α-helix	215-229	15
α-helix	231-236	6
α-helix	239-249	11
α-helix	256-263	8
β-strand	271	1	54
β-strand	444	1	54
α-helix	447-450	4
α-helix	452-454	3
α-helix	458-460	3
α-helix	468-478	11
α-helix	483-489	7
β-strand	491-494	4	53
α-helix	496-499	4
α-helix	503-514	12
α-helix	520-521	2
β-strand	524	1	53
α-helix	532-542	11
α-helix	544-550	7
β-strand	552	1	51
α-helix	554-560	7
α-helix	563-566	4

9 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
RuvB-like 1	A, C, E	protein	456	Homo sapiens	Q9Y265 (AlphaFold model)
RuvB-like 2	B, D, F	protein	463	Homo sapiens	Q9Y230 (AlphaFold model)
Chromatin-remodeling ATPase INO80	G	protein	1290	Homo sapiens	Q9ULG1 (AlphaFold model)
Actin-related protein 5	H	protein	607	Homo sapiens	Q9H9F9 (AlphaFold model)
Histone H3.1	I, M	protein	136	Homo sapiens	P68431
Histone H4	J, N	protein	103	Homo sapiens	P62805
Histone H2A type 1-B/E	K, O	protein	130	Homo sapiens	P04908
Histone H2B type 1-J	L, P	protein	126	Homo sapiens	P06899
INO80 complex subunit B	R	protein	356	Homo sapiens	Q9C086
DNA (150-mer)	X	DNA	228	synthetic construct
DNA (150-mer)	Y	DNA	228	synthetic construct

Sequence of entity 1 (A, C, E), FASTA

>6HTS_1 RuvB-like 1 (chains A, C, E)
MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK
MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI
GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL
QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL
HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF
VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI
IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN
GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK

Sequence of entity 2 (B, D, F), FASTA

>6HTS_2 RuvB-like 2 (chains B, D, F)
MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVL
EMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALT
QAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIE
SLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVH
TVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDE
VHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTT
PYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTE
VQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGETMDTS

Sequence of entity 3 (G), FASTA

>6HTS_3 Chromatin-remodeling ATPase INO80 (chains G)
HLSIEQLNARRRKVWLSIVKKELPKANKQKASARNLFLTNSRKLAHQCMKEVRRAALQAQ
KNCKETLPRARRLTKEMLLYWKKYEKVEKEHRKRAEKEALEQRKLDEEMREAKRQQRKLN
FLITQTELYAHFMSRKRDMGHDGIQEEILRKLEDSSTQRQIDIGGGVVVNITQEDYDSNH
FKAQALKNAENAYHIHQARTRSFDEDAKESRAAALRAANKSGTGFGESYSLANPSIRAGE
DIPQPTIFNGKLKGYQLKGMNWLANLYEQGINGILADEMGLGKTVQSIALLAHLAERENI
WGPFLIISPASTLNNWHQEFTRFVPKFKVLPYWGNPHDRKVIRRFWSQKTLYTQDAPFHV
VITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSSSSVRWKILLQFQCRNRLLLTGTPIQN
TMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHAENKSAIDENQLSRLHMILKPFMLRR
IKKDVENELSDKIEILMYCQLTSRQKLLYQALKNKISIEDLLQSSMGSTQQAQNTTSSLM
NLVMQFRKVCNHPELFERQETWSPFHISLKPYHISKFIYRHGQIRVFNHSRDRWLRVLSP
FAPDYIQRSLFHRKGINEESCFSFLRFIDISPAEMANLMLQGLLARWLALFLSLKASYRL
HQLRSWGAPEGESHQRYLRNKDFLLGVNFPLSFPNLCSCPLLKSLVFSSHCKAVSGYSDQ
VVHQRRSATSSLRRCLLTELPSFLCVASPRVTAVPLDSYCNDRSAEYERRVLKEGGSLAA
KQCLLNGAPELAADWLNRRSQFFPEPAGGLWSIRPQNGWSFIRIPGKESLITDSGKLYAL
DVLLTRLKSQGHRVLIYSQMTRMIDLLEEYMVYRKHTYMRLDGSSKISERRDMVADFQNR
NDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLIC
KGTIEERILQRAKEKSEIQRMVISGGNFKPDTLKPKEVVSLLLDDEELEKKLRLRQEEKR
QQEETNRVKERKRKREKYAEKKKKEDELDGKRRKEGVNLVIPFVPSADNSNLSADGDDSF
ISVDSAMPSPFSEISISSELHTGSIPLDESSSDMLVIVDDPASSAPQSRATNSPASITGS
VSDTVNGISIQEMPAAGRGHSARSRGRPKGSGSTAKGAGKGRSRKSTAGSAAAMAGAKAG
AAAASAAAYAAYGYNVSKGISASSPLQTSLVRPAGLADFGPSSASSPLSSPLSKGNNVPG
NPKNLHMTSSLAPDSLVRKQGKGTNPSGGR

Sequence of entity 4 (H), FASTA

>6HTS_4 Actin-related protein 5 (chains H)
MAANVFPFRDARAAPDPVLEAGPVAHGPLPVPLVLDNGSFQVRAGWACPGQDPGPEPRLQ
FRAVCARGRGGARGASGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHL
GVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPKNSM
CSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLS
RMEEILHEHSYIAEDYVEELHKWRCPDYYENNVHKMQLPFSSKLLGSTLTSEEKQERRQQ
QLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKALIELNMDSPEELQSY
IQKLSIAVEQAKQKILQAEVNLEVDVVDSKPETPDLEQLEPSLEDVESMNDFDPLFSEET
PGVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLQYILDRYP
KDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSSFQVQLASNPVLDAWYGARDW
ALNHLDDNEVWITRKEYEEKGGEYLKEHCASNIYVPIRLPKQASRSSDAQASSKGSAAGG
GGAGEQA

Sequence of entity 5 (I, M), FASTA

>6HTS_5 Histone H3.1 (chains I, M)
MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE
LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI
MPKDIQLARRIRGERA

Sequence of entity 6 (J, N), FASTA

>6HTS_6 Histone H4 (chains J, N)
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLK
VFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG

Sequence of entity 7 (K, O), FASTA

>6HTS_7 Histone H2A type 1-B/E (chains K, O)
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK
TESHHKAKGK

Sequence of entity 8 (L, P), FASTA

>6HTS_8 Histone H2B type 1-J (chains L, P)
MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAM
GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT
KYTSAK

Sequence of entity 9 (R), FASTA

>6HTS_9 INO80 complex subunit B (chains R)
MSKLWRRGSTSGAMEAPEPGEALELSLAGAHGHGVHKKKHKKHKKKHKKKHHQEEDAGPT
QPSPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPMEGVPLEQYR
AWLDEDSNLSPSPLRDLSGGLGGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQ
RALLQKARSQPSPMLPLPVAEGCPPPALTEEMLLKREERARKRRLQAARRAEEHKNQTIE
RLTKTAATSGRGGRGGARGERRGGRAAAPAPMVRYCSGAQGSTLSFPPGVPAPTAVSQRP
SPSGPPPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQMRLGGPEGPGSPLLAT

Sequence of entity 10 (X), FASTA

>6HTS_10 DNA (150-MER) (chains X)
GTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACCCCGAGTACATGCACAGGATG
TATATATCTGACACGTGCCTGGAGACTAGGGAGTAATCCCCTTGGCGGTTAAAACGCGGG
GGACAGCGCGTACGTGCGTTTAAGCGGTGCTAGAGCTGTCTACGACCAATTGAGCGGCCT
CGGCACCGGGATTGTCCAGGGCGGCCGCGGATGCATTAATGCAGATTC

Sequence of entity 11 (Y), FASTA

>6HTS_11 DNA (150-MER) (chains Y)
GAATCTGCATTAATGCATCCGCGGCCGCCCTGGACAATCCCGGTGCCGAGGCCGCTCAAT
TGGTCGTAGACAGCTCTAGCACCGCTTAAACGCACGTACGCGCTGTCCCCCGCGTTTTAA
CCGCCAAGGGGATTACTCCCTAGTCTCCAGGCACGTGTCAGATATATACATCCTGTGCAT
GTACTCGGGGTGGCGATAAGTCGTGTCTTACCGGGTTGGACTCAAGAC

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	1
ADP	Adenosine-5'-diphosphate	C10 H15 N5 O10 P2	6

Primary citation

Structure and regulation of the human INO80-nucleosome complex. Ayala, R., Willhoft, O., Aramayo, R.J. et al. Nature (2018) 556:391-395. DOI 10.1038/s41586-018-0021-6 · PubMed

Other PDB entries of the same protein (UniProt Q9Y265 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2C9O 2.2 Å, 3D Structure of the human RuvB-like helicase RuvBL1
8QR1 2.4 Å, Cryo-EM structure of the human Tip60 complex
9EMA 2.4 Å, RUVBL1/2 in complex with ATP and CB-6644 inhibitor
6K0R 2.5 Å, Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin
9C57 2.75 Å, Reconstituted P400 Subcomplex of the human TIP60 complex
2XSZ 3.0 Å, The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II
9CAE 3.07 Å, Cryo-EM structure of the reconstituted RuvBL lobe of the human TIP60 complex (composite…
7ZI4 3.2 Å, Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
8X15 3.2 Å, Structure of nucleosome-bound SRCAP-C in the apo state
8X19 3.2 Å, Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
8X1C 3.2 Å, Structure of nucleosome-bound SRCAP-C in the ADP-bound state
8XVT 3.2 Å, The core subcomplex of human NuA4/TIP60 complex

Browse structure collections

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