6M62: Probable metalloprotease ARX1
Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta 255-344 strain, C4 state. Determined by electron microscopy at 3.2 Å resolution. Released 26 Aug 2020.
- Method
- Electron microscopy
- Resolution
- 3.2 Å
- Organisms
- Saccharomyces cerevisiae S288C, Saccharomyces cerevisiae S288c
- Chains
- 58
- Atoms
- 153,289
- Mol. weight
- 2669.35 kDa
- Ligands
- ZN, GTP, MG
- Released
- 26 Aug 2020
Explore 6M62 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6M62 contains 413 α-helices and 443 β-strands across 54 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 4: 17 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-27 | 6 | |
| α-helix | 30-45 | 16 | |
| α-helix | 61-76 | 16 | |
| β-strand | 91-97 | 7 | 22 |
| β-strand | 100 | 1 | 23 |
| α-helix | 111-117 | 7 | |
| α-helix | 126-130 | 5 | |
| β-strand | 139-147 | 9 | 22 |
| β-strand | 150-158 | 9 | 22 |
| α-helix | 171-173 | 3 | |
| α-helix | 180-201 | 22 | |
| α-helix | 220-234 | 15 | |
| β-strand | 237-238 | 2 | 22 |
| α-helix | 239 | 1 | |
| β-strand | 243-247 | 5 | 22 |
| β-strand | 248 | 1 | 24 |
| β-strand | 251 | 1 | 24 |
| β-strand | 266-268 | 3 | 22 |
| α-helix | 272-275 | 4 | |
| β-strand | 315-324 | 10 | 22 |
| β-strand | 333-339 | 7 | 23 |
| β-strand | 360-361 | 2 | 25 |
| α-helix | 373-384 | 12 | |
| β-strand | 390 | 1 | 25 |
| α-helix | 406-428 | 23 | |
| β-strand | 433-434 | 2 | 25 |
| β-strand | 438-444 | 7 | 23 |
| α-helix | 445-448 | 4 | |
| α-helix | 482-490 | 9 | |
| β-strand | 500-509 | 10 | 22 |
| β-strand | 523-525 | 3 | 22 |
| α-helix | 529-532 | 4 | |
| α-helix | 533-536 | 4 | |
| α-helix | 548-559 | 12 | |
| β-strand | 570 | 1 | 22 |
Chain 5: 2 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 45-96 | 52 | |
| α-helix | 101-111 | 11 | |
Chain a: 5 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 78-81 | 4 | |
| α-helix | 84-91 | 8 | |
| β-strand | 101-103 | 3 | 61 |
| α-helix | 104-107 | 4 | |
| β-strand | 111-112 | 2 | 62 |
| β-strand | 124-127 | 4 | 61 |
| β-strand | 129-130 | 2 | 62 |
| α-helix | 132-141 | 10 | |
| β-strand | 145-147 | 3 | 61 |
| α-helix | 148 | 1 | |
Chain A: 6 helices, 19 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-12 | 7 | |
| β-strand | 18 | 1 | 55 |
| α-helix | 34-38 | 5 | |
| β-strand | 40-47 | 8 | 56 |
| β-strand | 50 | 1 | 57 |
| α-helix | 51 | 1 | |
| β-strand | 57 | 1 | 57 |
| β-strand | 58-64 | 7 | 56 |
| β-strand | 71-77 | 7 | 56 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 58 |
| β-strand | 83 | 1 | 59 |
| β-strand | 87-91 | 5 | 56 |
| β-strand | 101-103 | 3 | 56 |
| β-strand | 112-114 | 3 | 56 |
| β-strand | 116 | 1 | 60 |
| β-strand | 126 | 1 | 60 |
| β-strand | 134-139 | 6 | 56 |
| β-strand | 145-149 | 5 | 56 |
| β-strand | 155-159 | 5 | 56 |
| β-strand | 163-166 | 4 | 56 |
| α-helix | 168 | 1 | |
| β-strand | 169 | 1 | 58 |
| α-helix | 182-189 | 8 | |
| β-strand | 193 | 1 | 55 |
Chain b: 29 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-27 | 14 | |
| α-helix | 39-67 | 29 | |
| α-helix | 76-86 | 11 | |
| α-helix | 88-116 | 29 | |
| α-helix | 122-141 | 20 | |
| α-helix | 144-157 | 14 | |
| β-strand | 170-174 | 5 | 67 |
| α-helix | 180-187 | 8 | |
| β-strand | 205-211 | 7 | 67 |
| β-strand | 214-220 | 7 | 67 |
| α-helix | 236-245 | 10 | |
| β-strand | 249-254 | 6 | 67 |
| α-helix | 264-274 | 11 | |
| α-helix | 275-277 | 3 | |
| β-strand | 284-288 | 5 | 67 |
| α-helix | 295-297 | 3 | |
| α-helix | 300-309 | 10 | |
| β-strand | 317-320 | 4 | 67 |
| α-helix | 325-347 | 23 | |
| α-helix | 354-361 | 8 | |
| α-helix | 380-382 | 3 | |
| α-helix | 386-388 | 3 | |
| α-helix | 400-406 | 7 | |
| α-helix | 425-429 | 5 | |
| α-helix | 441-444 | 4 | |
| α-helix | 449-464 | 16 | |
| α-helix | 486-511 | 26 | |
| α-helix | 513-516 | 4 | |
| α-helix | 521-523 | 3 | |
| α-helix | 532-537 | 6 | |
| α-helix | 543-555 | 13 | |
| α-helix | 562-567 | 6 | |
| α-helix | 596-610 | 15 | |
| α-helix | 613-615 | 3 | |
| α-helix | 632-634 | 3 | |
Chain B: 12 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 27-29 | 3 | |
| α-helix | 40-41 | 2 | |
| β-strand | 43 | 1 | 63 |
| β-strand | 45-60 | 16 | 64 |
| β-strand | 70-80 | 11 | 64 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-96 | 13 | 65 |
| β-strand | 98-106 | 9 | 65 |
| α-helix | 112-117 | 6 | |
| α-helix | 131-137 | 7 | |
| α-helix | 143-153 | 11 | |
| β-strand | 157-163 | 7 | 65 |
| α-helix | 166-168 | 3 | |
| β-strand | 178-182 | 5 | 65 |
| β-strand | 183 | 1 | 63 |
| α-helix | 188-197 | 10 | |
| β-strand | 202-203 | 2 | 65 |
| β-strand | 214-221 | 8 | 64 |
| β-strand | 225-227 | 3 | 66 |
| α-helix | 229-232 | 4 | |
| β-strand | 268-270 | 3 | 66 |
| β-strand | 273-286 | 14 | 64 |
| α-helix | 307 | 1 | |
| β-strand | 321-325 | 5 | 64 |
| β-strand | 335-339 | 5 | 64 |
| α-helix | 348-350 | 3 | |
| β-strand | 356-359 | 4 | 64 |
| α-helix | 373-380 | 8 | |
Chain c: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-14 | 5 | |
| β-strand | 22-25 | 4 | 72 |
| α-helix | 28-36 | 9 | |
| β-strand | 41-44 | 4 | 72 |
| α-helix | 50-63 | 14 | |
| β-strand | 66-69 | 4 | 72 |
| α-helix | 74-80 | 7 | |
| β-strand | 89-94 | 6 | 72 |
Chain C: 18 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 8-9 | 2 | 68 |
| β-strand | 15 | 1 | 68 |
| α-helix | 32-43 | 12 | |
| β-strand | 63 | 1 | 69 |
| β-strand | 76 | 1 | 69 |
| β-strand | 88 | 1 | 69 |
| α-helix | 115-128 | 14 | |
| α-helix | 134-137 | 4 | |
| β-strand | 150-152 | 3 | 68 |
| α-helix | 154-156 | 3 | |
| α-helix | 162-172 | 11 | |
| α-helix | 175-180 | 6 | |
| β-strand | 186-187 | 2 | 70 |
| β-strand | 199-200 | 2 | 70 |
| β-strand | 206-209 | 4 | 68 |
| α-helix | 215-220 | 6 | |
| β-strand | 226-229 | 4 | 68 |
| α-helix | 235-238 | 4 | |
| α-helix | 240-242 | 3 | |
| β-strand | 248-251 | 4 | 68 |
| α-helix | 252-262 | 11 | |
| β-strand | 264 | 1 | 71 |
| β-strand | 267 | 1 | 71 |
| α-helix | 287-290 | 4 | |
| α-helix | 293-297 | 5 | |
| α-helix | 307-309 | 3 | |
| α-helix | 314-316 | 3 | |
| α-helix | 321-326 | 6 | |
| α-helix | 331-337 | 7 | |
| α-helix | 339-341 | 3 | |
| α-helix | 353-360 | 8 | |
46 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| RDN25-1 rRNA | 1 | RNA | 3396 | Saccharomyces cerevisiae S288C | |
| RDN58-1 rRNA | 2 | RNA | 158 | Saccharomyces cerevisiae S288C | |
| RDN5-2 rRNA | 3 | RNA | 121 | Saccharomyces cerevisiae S288C | |
| Probable metalloprotease ARX1 | 4 | protein | 593 | Saccharomyces cerevisiae S288C | Q03862 (AlphaFold model) |
| rRNA-processing protein CGR1 | 5 | protein | 120 | Saccharomyces cerevisiae S288c | P53188 (AlphaFold model) |
| ITS2-1 miscRNA | 6 | RNA | 232 | Saccharomyces cerevisiae S288C | |
| 60S ribosomal protein L2-A | A | protein | 254 | Saccharomyces cerevisiae S288c | P0CX45 (AlphaFold model) |
| 60S ribosomal protein L3 | B | protein | 387 | Saccharomyces cerevisiae S288c | P14126 (AlphaFold model) |
| 60S ribosomal protein L4-A | C | protein | 362 | Saccharomyces cerevisiae S288c | P10664 |
| 60S ribosomal protein L5 | D | protein | 297 | Saccharomyces cerevisiae S288c | P26321 |
| 60S ribosomal protein L6-A | E | protein | 176 | Saccharomyces cerevisiae S288c | Q02326 |
| 60S ribosomal protein L7-A | F | protein | 244 | Saccharomyces cerevisiae S288c | P05737 |
46 more molecules are not listed.
Sequence of entity 1 (1), FASTA
>6M62_1 RDN25-1 rRNA (chains 1)
GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGU
GCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUC
UCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCU
UGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACG
UAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGA
GUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUA
GGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGA
GUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCC
AGAGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUG
GGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCU
CAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGG
GUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAA
UUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGG
CGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCA
CAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAA
GGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGC
GUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGG
AGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUG
GUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACG
UCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAG
GCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAU
AUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAG
UUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUU
AUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAA
UCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAG
GUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGU
AACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGC
GGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCU
UGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAA
CUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUG
GUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAA
GAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAA
AUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCU
AUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAG
AAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAU
AAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAA
UGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGA
UCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGA
UAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGG
UAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUC
GAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAA
CUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCU
CUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGA
ACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUA
CCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGC
GGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUC
UAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUA
CGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGC
GGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAU
UUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU
Sequence of entity 2 (2), FASTA
>6M62_2 RDN58-1 rRNA (chains 2)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU
Sequence of entity 3 (3), FASTA
>6M62_3 RDN5-2 rRNA (chains 3)
GGUUGCGGCCAUAUCUACCAGAAAGCACCGUUUCCCGUCCGAUCAACUGUAGUUAAGCUG
GUAAGAGCCUGACCGAGUAGUGUAGUGGGUGACCAUACGCGAAACUCAGGUGCUGCAAUC
U
Sequence of entity 4 (4), FASTA
>6M62_4 Probable metalloprotease ARX1 (chains 4)
MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLT
VPELCLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKG
KDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGK
ADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVP
GSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTN
VSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAY
VRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFPFVHENEEELQSLKKDLKSFR
LGMSEISNNYLCVESPIQIARWVPWDHILKATNPNGNLSYDATSTLTLPGHELPLPKLGV
SAIKLKSLMNSTKESISLPVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQ
HELNPQDSIVQGIFQLATLAKDKRFGLLLKETQPMKQKSVETSNGGVEETMKM
Sequence of entity 5 (5), FASTA
>6M62_5 rRNA-processing protein CGR1 (chains 5)
MVNETGESQKAAKGTPVSGKVWKAEKTPLRAKSRVVKNKKLTSWELKKQKRLEDKQFKER
LKALKDEKEEARQAKITMLKERREKKEENERYERLAAKMHAKKVERMRRREKRNKALKER
Sequence of entity 6 (6), FASTA
>6M62_6 ITS2-1 miscRNA (chains 6)
CCUUCUCAAACAUUCUGUUUGGUAGUGAGUGAUACUCUUUGGAGUUAACUUGAAAUUGCU
GGCCUUUUCAUUGGAUGUUUUUUUUCCAAAGAGAGGUUUCUCUGCGUGCUUGAGGUAUAA
UGCAAGUACGGUCGUUUUAGGUUUUACCAACUGCGGCUAAUCUUUUUUUAUACUGAGCGU
AUUGGAACGUUAUCGAUAAGAAGAGAGCGUCUAGGCGAACAAUGUUCUUAAA
Sequence of entity 7 (A), FASTA
>6M62_7 60S ribosomal protein L2-A (chains A)
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAK
VVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKP
GDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLL
KAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAA
RRTGLLRGSQKTQD
Sequence of entity 8 (B), FASTA
>6M62_8 60S ribosomal protein L3 (chains B)
MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDL
DRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAE
IQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDR
TKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWID
TASKFGKGRFQTPAEKHAFMGTLKKDL
Sequence of entity 9 (C), FASTA
>6M62_9 60S ribosomal protein L4-A (chains C)
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRY
ATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLK
VLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAP
GAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIR
PAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLK
HD
Sequence of entity 10 (D), FASTA
>6M62_10 60S ribosomal protein L5 (chains D)
MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDI
ICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYK
GVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRF
PGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIY
TSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Sequence of entity 11 (E), FASTA
>6M62_11 60S ribosomal protein L6-A (chains E)
MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLED
NTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEAN
LFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
Sequence of entity 12 (F), FASTA
>6M62_12 60S ribosomal protein L7-A (chains F)
MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAER
NIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVT
KATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILS
IDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLV
KSMN
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 4 |
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 2 |
| MG | Magnesium ion | Mg | 2 |
Primary citation
Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly. Micic, J., Li, Y., Wu, S. et al. Nat Commun (2020) 11:3751-3751. DOI 10.1038/s41467-020-17534-5 · PubMed
Other PDB entries of the same protein (UniProt Q03862 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7UOO 2.34 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
- 7V08 2.36 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1…
- 7UQB 2.43 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a…
- 7UQZ 2.44 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1…
- 8HFR 2.64 Å, NPC-trapped pre-60S particle
- 6YLG 3.0 Å, Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
- 3JCT 3.08 Å, Cryo-em structure of eukaryotic pre-60S ribosomal subunits
- 6YLH 3.1 Å, Rix1-Rea1 pre-60S particle - full composite structure
- 6RZZ 3.2 Å, Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
- 5APO 3.41 Å, Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally…
- 7Z34 3.8 Å, Structure of pre-60S particle bound to DRG1(AFG2).
- 6FT6 3.9 Å, Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors
Browse structure collections
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