6YLH: Probable metalloprotease ARX1
Rix1-Rea1 pre-60S particle - full composite structure. Determined by electron microscopy at 3.1 Å resolution. Released 29 Jul 2020.
- Method
- Electron microscopy
- Resolution
- 3.1 Å
- Organism
- Saccharomyces cerevisiae
- Chains
- 60
- Atoms
- 180,897
- Mol. weight
- 3358.97 kDa
- Ligands
- ZN, GTP, MG
- Released
- 29 Jul 2020
Explore 6YLH in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6YLH contains 680 α-helices and 561 β-strands across 57 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 0: 7 helices, 36 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 2-9 | 8 | 89 |
| β-strand | 13-17 | 5 | 89 |
| β-strand | 23-26 | 4 | 89 |
| β-strand | 37-40 | 4 | 90 |
| β-strand | 44-48 | 5 | 90 |
| β-strand | 54-59 | 6 | 90 |
| β-strand | 71-74 | 4 | 90 |
| β-strand | 81-85 | 5 | 91 |
| β-strand | 100 | 1 | 92 |
| α-helix | 101-103 | 3 | |
| β-strand | 110-114 | 5 | 91 |
| α-helix | 116-118 | 3 | |
| β-strand | 120-124 | 5 | 91 |
| β-strand | 129-134 | 6 | 91 |
| β-strand | 144-147 | 4 | 93 |
| β-strand | 154-157 | 4 | 93 |
| β-strand | 163-165 | 3 | 93 |
| α-helix | 169-172 | 4 | |
| β-strand | 183-185 | 3 | 93 |
| β-strand | 192-197 | 6 | 94 |
| β-strand | 210-216 | 7 | 94 |
| β-strand | 220-226 | 7 | 94 |
| β-strand | 249-255 | 7 | 94 |
| β-strand | 260-265 | 6 | 95 |
| β-strand | 271-276 | 6 | 95 |
| β-strand | 279-284 | 6 | 95 |
| β-strand | 286-288 | 3 | 96 |
| β-strand | 294-296 | 3 | 96 |
| β-strand | 310-311 | 2 | 94 |
| β-strand | 314-315 | 2 | 97 |
| β-strand | 337-338 | 2 | 97 |
| β-strand | 340-343 | 4 | 95 |
| β-strand | 347-352 | 6 | 98 |
| β-strand | 358-363 | 6 | 98 |
| β-strand | 367-372 | 6 | 98 |
| β-strand | 378-383 | 6 | 98 |
| β-strand | 395-403 | 9 | 89 |
| α-helix | 433-436 | 4 | |
| β-strand | 450-453 | 4 | 99 |
| α-helix | 457 | 1 | |
| β-strand | 458 | 1 | 92 |
| α-helix | 459 | 1 | |
| α-helix | 473-484 | 12 | |
Chain 4: 20 helices, 22 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-46 | 25 | |
| α-helix | 47-51 | 5 | |
| α-helix | 61-79 | 19 | |
| β-strand | 87-88 | 2 | 34 |
| β-strand | 94-97 | 4 | 34 |
| β-strand | 100-102 | 3 | 35 |
| α-helix | 111-117 | 7 | |
| α-helix | 118-120 | 3 | |
| α-helix | 126-130 | 5 | |
| β-strand | 138-147 | 10 | 34 |
| β-strand | 150-159 | 10 | 34 |
| α-helix | 171-172 | 2 | |
| α-helix | 179-200 | 22 | |
| α-helix | 220-234 | 15 | |
| β-strand | 236-238 | 3 | 34 |
| α-helix | 239 | 1 | |
| β-strand | 243-247 | 5 | 34 |
| β-strand | 248 | 1 | 36 |
| β-strand | 251 | 1 | 36 |
| β-strand | 266-268 | 3 | 34 |
| α-helix | 271-279 | 9 | |
| β-strand | 315-325 | 11 | 34 |
| β-strand | 333-339 | 7 | 35 |
| β-strand | 360-361 | 2 | 37 |
| α-helix | 373-384 | 12 | |
| β-strand | 390 | 1 | 37 |
| α-helix | 406-428 | 23 | |
| β-strand | 433-434 | 2 | 37 |
| β-strand | 438-444 | 7 | 35 |
| α-helix | 445-449 | 5 | |
| β-strand | 475 | 1 | 38 |
| β-strand | 480 | 1 | 38 |
| α-helix | 482-490 | 9 | |
| α-helix | 496 | 1 | |
| β-strand | 497 | 1 | 35 |
| α-helix | 498-499 | 2 | |
| β-strand | 500-509 | 10 | 34 |
| β-strand | 522-524 | 3 | 34 |
| α-helix | 529-532 | 4 | |
| α-helix | 548-560 | 13 | |
| β-strand | 569-571 | 3 | 34 |
| α-helix | 572-575 | 4 | |
Chain 5: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 43-108 | 66 | |
Chain 6: 35 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-13 | 6 | |
| α-helix | 20-29 | 10 | |
| α-helix | 33-35 | 3 | |
| α-helix | 45-57 | 13 | |
| α-helix | 63-77 | 15 | |
| α-helix | 79-102 | 24 | |
| α-helix | 113-128 | 16 | |
| α-helix | 135-138 | 4 | |
| α-helix | 143-157 | 15 | |
| α-helix | 161-174 | 14 | |
| α-helix | 180-182 | 3 | |
| α-helix | 183-194 | 12 | |
| α-helix | 203-215 | 13 | |
| α-helix | 216-218 | 3 | |
| α-helix | 242-252 | 11 | |
| α-helix | 255-265 | 11 | |
| α-helix | 271-277 | 7 | |
| α-helix | 293-296 | 4 | |
| α-helix | 303-308 | 6 | |
| α-helix | 310-325 | 16 | |
| β-strand | 332-335 | 4 | 82 |
| α-helix | 336-346 | 11 | |
| α-helix | 365-390 | 26 | |
| α-helix | 397-399 | 3 | |
| α-helix | 402-410 | 9 | |
| α-helix | 412 | 1 | |
| β-strand | 413 | 1 | 107 |
| α-helix | 414 | 1 | |
| β-strand | 421 | 1 | 107 |
| α-helix | 423-426 | 4 | |
| α-helix | 431-447 | 17 | |
| α-helix | 455-467 | 13 | |
| β-strand | 471-472 | 2 | 108 |
| β-strand | 515-516 | 2 | 108 |
| α-helix | 517-519 | 3 | |
| α-helix | 520-535 | 16 | |
| α-helix | 542-561 | 20 | |
| α-helix | 567-578 | 12 | |
| α-helix | 588-594 | 7 | |
| α-helix | 602-607 | 6 | |
Chain 7: 37 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-15 | 8 | |
| α-helix | 20-30 | 11 | |
| α-helix | 39-41 | 3 | |
| α-helix | 45-57 | 13 | |
| α-helix | 63-76 | 14 | |
| α-helix | 79-101 | 23 | |
| α-helix | 105-108 | 4 | |
| α-helix | 113-131 | 19 | |
| α-helix | 135-138 | 4 | |
| α-helix | 143-156 | 14 | |
| α-helix | 161-174 | 14 | |
| α-helix | 177-182 | 6 | |
| α-helix | 183-195 | 13 | |
| α-helix | 203-215 | 13 | |
| α-helix | 216-218 | 3 | |
| α-helix | 242-251 | 10 | |
| α-helix | 255-260 | 6 | |
| α-helix | 261-263 | 3 | |
| β-strand | 265 | 1 | 113 |
| α-helix | 273-278 | 6 | |
| α-helix | 308-324 | 17 | |
| β-strand | 332-335 | 4 | 99 |
| α-helix | 336-348 | 13 | |
| α-helix | 355 | 1 | |
| β-strand | 356 | 1 | 113 |
| α-helix | 357 | 1 | |
| α-helix | 361-362 | 2 | |
| α-helix | 364-390 | 27 | |
| α-helix | 397-399 | 3 | |
| α-helix | 400-405 | 6 | |
| α-helix | 406-410 | 5 | |
| β-strand | 413 | 1 | 114 |
| β-strand | 421 | 1 | 114 |
| α-helix | 423-426 | 4 | |
| α-helix | 427-429 | 3 | |
| α-helix | 430-444 | 15 | |
| α-helix | 454-468 | 15 | |
| α-helix | 522-536 | 15 | |
| α-helix | 541-561 | 21 | |
| α-helix | 567-578 | 12 | |
| α-helix | 590-596 | 7 | |
| α-helix | 602-607 | 6 | |
| β-strand | 616-617 | 2 | 80 |
Chain a: 3 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 72-74 | 3 | 87 |
| α-helix | 84-92 | 9 | |
| β-strand | 99-100 | 2 | 148 |
| β-strand | 101-103 | 3 | 88 |
| α-helix | 104-107 | 4 | |
| β-strand | 111-113 | 3 | 87 |
| β-strand | 124-127 | 4 | 88 |
| β-strand | 129-130 | 2 | 87 |
| α-helix | 132-141 | 10 | |
| β-strand | 145-147 | 3 | 88 |
Chain A: 6 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-9 | 4 | |
| α-helix | 29-31 | 3 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 83 |
| β-strand | 58-64 | 7 | 83 |
| β-strand | 71-77 | 7 | 83 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 84 |
| β-strand | 83 | 1 | 85 |
| β-strand | 87-91 | 5 | 83 |
| β-strand | 101-103 | 3 | 83 |
| β-strand | 112-114 | 3 | 83 |
| β-strand | 116 | 1 | 86 |
| β-strand | 126 | 1 | 86 |
| β-strand | 134-140 | 7 | 83 |
| β-strand | 145-149 | 5 | 83 |
| β-strand | 155-159 | 5 | 83 |
| β-strand | 163-166 | 4 | 83 |
| β-strand | 169 | 1 | 84 |
| α-helix | 182-192 | 11 | |
| α-helix | 201-203 | 3 | |
Chain b: 24 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-28 | 15 | |
| α-helix | 39-67 | 29 | |
| α-helix | 76-86 | 11 | |
| α-helix | 88-101 | 14 | |
| α-helix | 105-116 | 12 | |
| α-helix | 122-141 | 20 | |
| α-helix | 144-159 | 16 | |
| β-strand | 169-174 | 6 | 104 |
| α-helix | 180-187 | 8 | |
| β-strand | 205-210 | 6 | 104 |
| β-strand | 215-220 | 6 | 104 |
| α-helix | 234-245 | 12 | |
| β-strand | 249-253 | 5 | 104 |
| α-helix | 264-274 | 11 | |
| α-helix | 275-280 | 6 | |
| β-strand | 283-287 | 5 | 104 |
| α-helix | 301-310 | 10 | |
| β-strand | 317-319 | 3 | 104 |
| α-helix | 326-346 | 21 | |
| α-helix | 380-384 | 5 | |
| α-helix | 400-406 | 7 | |
| β-strand | 435 | 1 | 105 |
| β-strand | 440 | 1 | 105 |
| α-helix | 441-444 | 4 | |
| α-helix | 450-465 | 16 | |
| β-strand | 478 | 1 | 106 |
| β-strand | 481 | 1 | 106 |
| α-helix | 484-511 | 28 | |
| α-helix | 513-516 | 4 | |
| α-helix | 530-538 | 9 | |
| α-helix | 543-556 | 14 | |
| α-helix | 562-567 | 6 | |
| α-helix | 596-609 | 14 | |
| α-helix | 611-615 | 5 | |
49 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 25S rRNA | 1 | RNA | 3396 | Saccharomyces cerevisiae | |
| 5.8S rRNA | 2 | RNA | 158 | Saccharomyces cerevisiae | |
| 5S rRNA | 3 | RNA | 121 | Saccharomyces cerevisiae | |
| Probable metalloprotease ARX1 | 4 | protein | 593 | Saccharomyces cerevisiae | Q03862 (AlphaFold model) |
| rRNA-processing protein CGR1 | 5 | protein | 120 | Saccharomyces cerevisiae | P53188 (AlphaFold model) |
| 60S ribosomal protein L2-A | A | protein | 254 | Saccharomyces cerevisiae | P0CX45 (AlphaFold model) |
| 60S ribosomal protein L3 | B | protein | 387 | Saccharomyces cerevisiae | P14126 (AlphaFold model) |
| 60S ribosomal protein L4-A | C | protein | 362 | Saccharomyces cerevisiae | P10664 |
| 60S ribosomal protein L5 | D | protein | 297 | Saccharomyces cerevisiae | P26321 |
| 60S ribosomal protein L6-A | E | protein | 176 | Saccharomyces cerevisiae | Q02326 |
| 60S ribosomal protein L7-A | F | protein | 244 | Saccharomyces cerevisiae | P05737 |
| 60S ribosomal protein L8-A | G | protein | 256 | Saccharomyces cerevisiae | P17076 |
46 more molecules are not listed.
Sequence of entity 1 (1), FASTA
>6YLH_1 25S rRNA (chains 1)
GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGU
GCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUC
UCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCU
UGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACG
UAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGA
GUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUA
GGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGA
GUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCC
AGAGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUG
GGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCU
CAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGG
GUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAA
UUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGG
CGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCA
CAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAA
GGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGC
GUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGG
AGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUG
GUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACG
UCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAG
GCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAU
AUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAG
UUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUU
AUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAA
UCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAG
GUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGU
AACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGC
GGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCU
UGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAA
CUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUG
GUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAA
GAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAA
AUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCU
AUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAG
AAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAU
AAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAA
UGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGA
UCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGA
UAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGG
UAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUC
GAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAA
CUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCU
CUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGA
ACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUA
CCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGC
GGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUC
UAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUA
CGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGC
GGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAU
UUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU
Sequence of entity 2 (2), FASTA
>6YLH_2 5.8S rRNA (chains 2)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU
Sequence of entity 3 (3), FASTA
>6YLH_3 5S rRNA (chains 3)
GGUUGCGGCCAUAUCUACCAGAAAGCACCGUUUCCCGUCCGAUCAACUGUAGUUAAGCUG
GUAAGAGCCUGACCGAGUAGUGUAGUGGGUGACCAUACGCGAAACUCAGGUGCUGCAAUC
U
Sequence of entity 4 (4), FASTA
>6YLH_4 Probable metalloprotease ARX1 (chains 4)
MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLT
VPELCLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKG
KDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGK
ADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVP
GSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTN
VSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAY
VRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFPFVHENEEELQSLKKDLKSFR
LGMSEISNNYLCVESPIQIARWVPWDHILKATNPNGNLSYDATSTLTLPGHELPLPKLGV
SAIKLKSLMNSTKESISLPVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQ
HELNPQDSIVQGIFQLATLAKDKRFGLLLKETQPMKQKSVETSNGGVEETMKM
Sequence of entity 5 (5), FASTA
>6YLH_5 rRNA-processing protein CGR1 (chains 5)
MVNETGESQKAAKGTPVSGKVWKAEKTPLRAKSRVVKNKKLTSWELKKQKRLEDKQFKER
LKALKDEKEEARQAKITMLKERREKKEENERYERLAAKMHAKKVERMRRREKRNKALKER
Sequence of entity 6 (A), FASTA
>6YLH_6 60S ribosomal protein L2-A (chains A)
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAK
VVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKP
GDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLL
KAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAA
RRTGLLRGSQKTQD
Sequence of entity 7 (B), FASTA
>6YLH_7 60S ribosomal protein L3 (chains B)
MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDL
DRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAE
IQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDR
TKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWID
TASKFGKGRFQTPAEKHAFMGTLKKDL
Sequence of entity 8 (C), FASTA
>6YLH_8 60S ribosomal protein L4-A (chains C)
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRY
ATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLK
VLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAP
GAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIR
PAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLK
HD
Sequence of entity 9 (D), FASTA
>6YLH_9 60S ribosomal protein L5 (chains D)
MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDI
ICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYK
GVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRF
PGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIY
TSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Sequence of entity 10 (E), FASTA
>6YLH_10 60S ribosomal protein L6-A (chains E)
MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLED
NTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEAN
LFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
Sequence of entity 11 (F), FASTA
>6YLH_11 60S ribosomal protein L7-A (chains F)
MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAER
NIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVT
KATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILS
IDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLV
KSMN
Sequence of entity 12 (G), FASTA
>6YLH_12 60S ribosomal protein L8-A (chains G)
MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQR
QKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGK
SKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIV
KGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGN
KAQAKMDKRAKNSDSA
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 4 |
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 2 |
| MG | Magnesium ion | Mg | 2 |
Primary citation
Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. Kater, L., Mitterer, V., Thoms, M. et al. Mol Cell (2020) 79:615-628.e5. DOI 10.1016/j.molcel.2020.06.032 · PubMed
Other PDB entries of the same protein (UniProt Q03862 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7UOO 2.34 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
- 7V08 2.36 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1…
- 7UQB 2.43 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a…
- 7UQZ 2.44 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1…
- 8HFR 2.64 Å, NPC-trapped pre-60S particle
- 6YLG 3.0 Å, Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
- 3JCT 3.08 Å, Cryo-em structure of eukaryotic pre-60S ribosomal subunits
- 6M62 3.2 Å, Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae…
- 6RZZ 3.2 Å, Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
- 5APO 3.41 Å, Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally…
- 7Z34 3.8 Å, Structure of pre-60S particle bound to DRG1(AFG2).
- 6FT6 3.9 Å, Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors
Browse structure collections
About this viewer
MolViewer shows 6YLH directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.