Human SDS22. Determined by X-ray diffraction at 2.9 Å resolution. Released 12 Dec 2018.
Explore 6MKY in 3D Show helices and sheets RCSB PDB PDBe
6MKY contains 6 α-helices and 26 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 102-104 | 3 | 1 |
| β-strand | 124-126 | 3 | 1 |
| β-strand | 146-148 | 3 | 1 |
| β-strand | 168-170 | 3 | 1 |
| β-strand | 190-192 | 3 | 1 |
| β-strand | 212-214 | 3 | 1 |
| β-strand | 234-236 | 3 | 1 |
| β-strand | 256-258 | 3 | 1 |
| β-strand | 278-280 | 3 | 1 |
| β-strand | 300-302 | 3 | 1 |
| α-helix | 311-319 | 9 | |
| β-strand | 325-327 | 3 | 1 |
| α-helix | 332-335 | 4 | |
| α-helix | 339-346 | 8 | |
| β-strand | 352-353 | 2 | 1 |
| β-strand | 356-357 | 2 | 1 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Protein phosphatase 1 regulatory subunit 7 | A, B | protein | 261 | Homo sapiens | Q15435 (AlphaFold model) |
>6MKY_1 Protein phosphatase 1 regulatory subunit 7 (chains A, B) VKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEG VDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNK ITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTML DIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQY RRKVMLALPSVRQIDATFVRF
The structure of SDS22 provides insights into the mechanism of heterodimer formation with PP1. Choy, M.S., Bolik-Coulon, N., Archuleta, T.L. et al. Acta Crystallogr F Struct Biol Commun (2018) 74:817-824. DOI 10.1107/S2053230X18016503 · PubMed
Other PDB entries of the same protein (UniProt Q15435 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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