6NC4: FtsY-NG high-resolution

FtsY-NG high-resolution. Determined by X-ray diffraction at 1.6 Å resolution. Released 23 Oct 2019.

Method: X-ray diffraction
Resolution: 1.6 Å
Organism: Escherichia coli (strain K12)
Chains: 2
Atoms: 5,268
Mol. weight: 68.09 kDa
Ligands: GDP, GNP
Released: 23 Oct 2019

Explore 6NC4 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6NC4 contains 34 α-helices and 21 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 16 helices, 11 β-strands

Element	Residues	Length	Sheet
α-helix	197-202	6
α-helix	204-207	4
α-helix	213-218	6
β-strand	222	1	1
α-helix	225-237	13
α-helix	242-258	17
β-strand	263	1	1
α-helix	264-266	3
α-helix	267-280	14
β-strand	283	1	2
β-strand	294-299	6	2
α-helix	306-319	14
β-strand	324-329	6	2
α-helix	334-347	14
β-strand	351-352	2	2
α-helix	360-373	14
β-strand	378-383	6	2
α-helix	390-404	15
β-strand	414-420	7	2
α-helix	421-423	3
α-helix	426-437	12
β-strand	442-446	5	2
α-helix	456-464	9
β-strand	468-472	5	2
α-helix	477-479	3
β-strand	480-482	3	2
α-helix	485-493	9

Chain B: 18 helices, 10 β-strands

Element	Residues	Length	Sheet
α-helix	196-202	7
α-helix	204-207	4
α-helix	211-214	4
α-helix	215-218	4
β-strand	222	1	3
α-helix	225-237	13
α-helix	242-258	17
β-strand	263	1	3
α-helix	264-266	3
α-helix	267-280	14
α-helix	284-286	3
β-strand	294-299	6	4
α-helix	306-319	14
β-strand	324-327	4	4
α-helix	334-347	14
β-strand	351-352	2	4
α-helix	360-373	14
β-strand	378-381	4	4
α-helix	390-407	18
β-strand	414-420	7	4
α-helix	421-423	3
α-helix	426-438	13
β-strand	442-446	5	4
α-helix	456-464	9
β-strand	468-472	5	4
α-helix	477-479	3
β-strand	480-482	3	4
α-helix	485-493	9

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Signal recognition particle receptor FtsY	A, B	protein	303	Escherichia coli (strain K12)	P10121 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>6NC4_1 Signal recognition particle receptor FtsY (chains A, B)
GFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTE
GASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLA
RQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKAR
NIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLF
HEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFA
RED

Ligands and cofactors

ID	Name	Formula	Copies
GDP	Guanosine-5'-diphosphate	C10 H15 N5 O11 P2	1
GNP	Phosphoaminophosphonic acid-guanylate ester	C10 H17 N6 O13 P3	1

Water and common crystallization additives (GOL, NH4, ACT) are not listed.

Primary citation

Structural insights into the G-loop dynamics of E. coli FtsY NG domain. Faoro, C., Ataide, S.F. J Struct Biol (2019) 208:107387-107387. DOI 10.1016/j.jsb.2019.09.004 · PubMed

Other PDB entries of the same protein (UniProt P10121 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6N9B 1.22 Å, FtsY-NG ultra high-resolution
6N5J 1.37 Å, FtsY-NG high-resolution
6CQP 1.45 Å, High resolution crystal structure of FtsY-NG domain of E. coli
6N5I 1.5 Å, FtsY-NG high-resolution
6NC1 1.6 Å, FtsY-NG high-resolution
2YHS 1.6 Å, Structure of the E. coli SRP receptor FtsY
5NIY 1.7 Å, Signal recognition particle-docking protein FtsY
6CS8 1.75 Å, High resolution crystal structure of FtsY-NG domain of E. coli
6CVD 1.78 Å, High resolution crystal structure of FtsY-NG domain of E. coli bound to fragment 1
6DLX 1.85 Å, FtsY-NG domain bound to fragment 3.
6N6N 1.88 Å, FtsY-NG high-resolution
2QY9 1.9 Å, Structure of the NG+1 construct of the E. coli SRP receptor FtsY

Browse structure collections

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