6RLB: Dynein-2 complex; tail domain
Structure of the dynein-2 complex; tail domain. Determined by electron microscopy at 4.5 Å resolution. Released 28 Aug 2019.
- Method
- Electron microscopy
- Resolution
- 4.5 Å
- Organism
- Homo sapiens
- Chains
- 14
- Atoms
- 20,407
- Mol. weight
- 1377.6 kDa
- Released
- 28 Aug 2019
Explore 6RLB in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6RLB contains 143 α-helices and 131 β-strands across 14 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain A: 43 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-21 | 10 | |
| α-helix | 26-28 | 3 | |
| α-helix | 36-44 | 9 | |
| β-strand | 50-56 | 7 | 1 |
| β-strand | 59-63 | 5 | 1 |
| β-strand | 74-80 | 7 | 1 |
| β-strand | 95-101 | 7 | 1 |
| α-helix | 106-111 | 6 | |
| α-helix | 112-116 | 5 | |
| α-helix | 117-122 | 6 | |
| α-helix | 131-149 | 19 | |
| α-helix | 192-209 | 18 | |
| α-helix | 212-214 | 3 | |
| α-helix | 217-234 | 18 | |
| α-helix | 245-268 | 24 | |
| α-helix | 277-308 | 32 | |
| α-helix | 323-346 | 24 | |
| α-helix | 348-350 | 3 | |
| α-helix | 352-366 | 15 | |
| α-helix | 379-408 | 30 | |
| α-helix | 414-423 | 10 | |
| α-helix | 425-428 | 4 | |
| α-helix | 431-436 | 6 | |
| α-helix | 438-460 | 23 | |
| α-helix | 482-506 | 25 | |
| α-helix | 511-545 | 35 | |
| α-helix | 546-550 | 5 | |
| α-helix | 555-557 | 3 | |
| β-strand | 558-560 | 3 | 2 |
| β-strand | 570-572 | 3 | 2 |
| α-helix | 576-591 | 16 | |
| α-helix | 598-631 | 34 | |
| α-helix | 637-655 | 19 | |
| α-helix | 657-660 | 4 | |
| α-helix | 663-666 | 4 | |
| α-helix | 669-706 | 38 | |
| α-helix | 715-733 | 19 | |
| α-helix | 739-767 | 29 | |
| α-helix | 773-774 | 2 | |
| β-strand | 775-782 | 8 | 3 |
| β-strand | 785-789 | 5 | 3 |
| α-helix | 792-807 | 16 | |
| α-helix | 823-831 | 9 | |
| α-helix | 835-860 | 26 | |
| α-helix | 868-875 | 8 | |
| α-helix | 879-896 | 18 | |
| β-strand | 902-904 | 3 | 3 |
| β-strand | 908-911 | 4 | 3 |
| α-helix | 913-956 | 44 | |
| α-helix | 964-966 | 3 | |
| α-helix | 970-983 | 14 | |
| α-helix | 986-1000 | 15 | |
| α-helix | 1006-1032 | 27 | |
Chain B: 42 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-21 | 10 | |
| α-helix | 26-28 | 3 | |
| α-helix | 36-44 | 9 | |
| β-strand | 50-56 | 7 | 1 |
| β-strand | 59-63 | 5 | 1 |
| β-strand | 74-80 | 7 | 1 |
| β-strand | 95-101 | 7 | 1 |
| α-helix | 106-110 | 5 | |
| α-helix | 111-116 | 6 | |
| α-helix | 117-122 | 6 | |
| α-helix | 131-149 | 19 | |
| α-helix | 192-210 | 19 | |
| α-helix | 217-234 | 18 | |
| α-helix | 245-268 | 24 | |
| α-helix | 277-308 | 32 | |
| α-helix | 323-346 | 24 | |
| α-helix | 352-366 | 15 | |
| α-helix | 375-377 | 3 | |
| α-helix | 378-408 | 31 | |
| α-helix | 414-423 | 10 | |
| α-helix | 425-428 | 4 | |
| α-helix | 431-436 | 6 | |
| α-helix | 438-460 | 23 | |
| α-helix | 468-471 | 4 | |
| α-helix | 475-478 | 4 | |
| α-helix | 482-507 | 26 | |
| α-helix | 511-545 | 35 | |
| α-helix | 546-550 | 5 | |
| α-helix | 557-559 | 3 | |
| β-strand | 560 | 1 | 4 |
| β-strand | 570 | 1 | 4 |
| α-helix | 575-591 | 17 | |
| α-helix | 598-630 | 33 | |
| α-helix | 631-633 | 3 | |
| α-helix | 637-654 | 18 | |
| α-helix | 657-660 | 4 | |
| α-helix | 663-666 | 4 | |
| α-helix | 669-706 | 38 | |
| α-helix | 711-733 | 23 | |
| α-helix | 739-767 | 29 | |
| α-helix | 769-771 | 3 | |
| α-helix | 773-774 | 2 | |
| β-strand | 775-782 | 8 | 5 |
| β-strand | 785-789 | 5 | 5 |
| α-helix | 792-807 | 16 | |
| α-helix | 823-831 | 9 | |
| α-helix | 835-860 | 26 | |
| α-helix | 869-875 | 7 | |
| α-helix | 879-896 | 18 | |
| β-strand | 902-904 | 3 | 5 |
| β-strand | 908-911 | 4 | 5 |
| α-helix | 913-935 | 23 | |
Chain C: 7 helices, 32 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 528-534 | 7 | 6 |
| β-strand | 540-545 | 6 | 7 |
| β-strand | 551-557 | 7 | 8 |
| α-helix | 580-583 | 4 | |
| α-helix | 586-606 | 21 | |
| β-strand | 630-631 | 2 | 9 |
| β-strand | 643-649 | 7 | 10 |
| β-strand | 656-662 | 7 | 10 |
| β-strand | 676-682 | 7 | 10 |
| α-helix | 686 | 1 | |
| β-strand | 691-695 | 5 | 10 |
| β-strand | 699-704 | 6 | 11 |
| β-strand | 711-716 | 6 | 11 |
| β-strand | 721-725 | 5 | 11 |
| β-strand | 735 | 1 | 12 |
| β-strand | 744 | 1 | 12 |
| β-strand | 765-771 | 7 | 13 |
| α-helix | 784-786 | 3 | |
| α-helix | 790-792 | 3 | |
| β-strand | 798-803 | 6 | 13 |
| β-strand | 808-811 | 4 | 13 |
| β-strand | 838-840 | 3 | 13 |
| β-strand | 865-868 | 4 | 14 |
| β-strand | 875-879 | 5 | 14 |
| β-strand | 885-889 | 5 | 14 |
| β-strand | 899-900 | 2 | 14 |
| β-strand | 914-917 | 4 | 15 |
| β-strand | 924-928 | 5 | 15 |
| β-strand | 933-938 | 6 | 15 |
| β-strand | 948-949 | 2 | 15 |
| β-strand | 957-962 | 6 | 16 |
| β-strand | 969-974 | 6 | 16 |
| β-strand | 978-983 | 6 | 16 |
| β-strand | 993-996 | 4 | 16 |
| β-strand | 1002-1010 | 9 | 9 |
| β-strand | 1018-1025 | 8 | 9 |
| β-strand | 1030-1033 | 4 | 9 |
| α-helix | 1036-1038 | 3 | |
| α-helix | 1043-1054 | 12 | |
Chain D: 8 helices, 31 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 60-66 | 7 | 6 |
| β-strand | 72-78 | 7 | 7 |
| β-strand | 82-88 | 7 | 8 |
| α-helix | 105-127 | 23 | |
| α-helix | 141-143 | 3 | |
| β-strand | 151-153 | 3 | 17 |
| α-helix | 158-160 | 3 | |
| β-strand | 163-169 | 7 | 18 |
| β-strand | 176-182 | 7 | 18 |
| β-strand | 195-199 | 5 | 18 |
| β-strand | 212-214 | 3 | 18 |
| β-strand | 220-225 | 6 | 19 |
| β-strand | 232-237 | 6 | 19 |
| β-strand | 242-246 | 5 | 19 |
| α-helix | 247-249 | 3 | |
| β-strand | 255-257 | 3 | 19 |
| β-strand | 272-276 | 5 | 20 |
| β-strand | 284-289 | 6 | 20 |
| β-strand | 295-298 | 4 | 20 |
| α-helix | 301-303 | 3 | |
| β-strand | 308 | 1 | 20 |
| β-strand | 337-342 | 6 | 21 |
| β-strand | 350-354 | 5 | 21 |
| β-strand | 360-362 | 3 | 21 |
| β-strand | 384-387 | 4 | 21 |
| α-helix | 394 | 1 | |
| β-strand | 395-399 | 5 | 22 |
| β-strand | 408-412 | 5 | 22 |
| β-strand | 417-420 | 4 | 22 |
| β-strand | 429-431 | 3 | 22 |
| β-strand | 438-442 | 5 | 23 |
| β-strand | 450-455 | 6 | 23 |
| β-strand | 460-464 | 5 | 23 |
| β-strand | 475-476 | 2 | 23 |
| α-helix | 482-485 | 4 | |
| β-strand | 487-490 | 4 | 17 |
| β-strand | 498-501 | 4 | 17 |
| β-strand | 507-510 | 4 | 17 |
| α-helix | 523-533 | 11 | |
Chain E: 13 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 5-16 | 12 | |
| β-strand | 33-38 | 6 | 24 |
| α-helix | 44-51 | 8 | |
| α-helix | 56-59 | 4 | |
| β-strand | 67-71 | 5 | 24 |
| β-strand | 80-88 | 9 | 24 |
| α-helix | 93-97 | 5 | |
| α-helix | 103-105 | 3 | |
| β-strand | 109-116 | 8 | 24 |
| α-helix | 120-144 | 25 | |
| α-helix | 151-160 | 10 | |
| β-strand | 181-186 | 6 | 24 |
| α-helix | 188-193 | 6 | |
| α-helix | 196-213 | 18 | |
| β-strand | 216-218 | 3 | 24 |
| α-helix | 226-234 | 9 | |
| β-strand | 256-257 | 2 | 24 |
| α-helix | 264-267 | 4 | |
| α-helix | 286-296 | 11 | |
| α-helix | 320-338 | 19 | |
Chain F: 14 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 5-16 | 12 | |
| α-helix | 29-31 | 3 | |
| β-strand | 33-38 | 6 | 25 |
| α-helix | 44-51 | 8 | |
| α-helix | 56-59 | 4 | |
| β-strand | 65-71 | 7 | 25 |
| β-strand | 80-88 | 9 | 25 |
| α-helix | 93-97 | 5 | |
| α-helix | 103-108 | 6 | |
| β-strand | 109-116 | 8 | 25 |
| α-helix | 120-144 | 25 | |
| α-helix | 151-160 | 10 | |
| β-strand | 181-186 | 6 | 25 |
| α-helix | 188-193 | 6 | |
| α-helix | 196-213 | 18 | |
| β-strand | 216-218 | 3 | 25 |
| α-helix | 226-234 | 9 | |
| β-strand | 256-257 | 2 | 25 |
| α-helix | 264-267 | 4 | |
| α-helix | 286-296 | 11 | |
| α-helix | 320-338 | 19 | |
Chain G: 2 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 605-613 | 9 | |
| β-strand | 618-624 | 7 | 26 |
| β-strand | 630-633 | 4 | 26 |
| α-helix | 637-661 | 25 | |
| β-strand | 667-674 | 8 | 26 |
| β-strand | 678-681 | 4 | 26 |
| β-strand | 689-693 | 5 | 26 |
Chain H: 2 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 512-520 | 9 | |
| β-strand | 525-533 | 9 | 26 |
| β-strand | 536-540 | 5 | 26 |
| α-helix | 544-568 | 25 | |
| β-strand | 574-581 | 8 | 26 |
| β-strand | 585-589 | 5 | 26 |
| β-strand | 596-600 | 5 | 26 |
2 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| O6-alkylguanine-DNA alkyltransferase mutant,DYNC2H1 variant protein | A, B | protein | 4513 | Homo sapiens | E5BBQ0 (AlphaFold model), Q8NCM8 (AlphaFold model) |
| WD repeat-containing protein 60 | C | protein | 1066 | Homo sapiens | Q8WVS4 (AlphaFold model) |
| WD repeat-containing protein 34 | D | protein | 564 | Homo sapiens | Q96EX3 (AlphaFold model) |
| Cytoplasmic dynein 2 light intermediate chain 1 | E, F | protein | 351 | Homo sapiens | Q8TCX1 |
| Dynein light chain roadblock-type 1 | G, H | protein | 96 | Homo sapiens | Q9NP97 |
| Dynein light chain 1, cytoplasmic | I, J, K, L, M, N | protein | 89 | Homo sapiens | P63167 |
Sequence of entity 1 (A, B), FASTA
>6RLB_1 O6-alkylguanine-DNA alkyltransferase mutant,DYNC2H1 variant protein (chains A, B)
GDKDCEMKRTTLDSPLGKLELSGCEQGLHRIIFLGKGTSAADAVEVPAPAAVLGGPEPLM
QATAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYSHLAAL
AGNPAATAAVKTALSGNPVPILIPCHRVVQGDLDVGGYEGGLAVKEWLLAHEGHRLGKPG
LGGSLEVLFQGPDYDIPTTLEVLFQGPANGTADVRKLFIFTTTQNYFGLMSELWDQPLLC
NCLEINNFLDDGNQMLLRVQRSDAGISFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDN
ILVSSMLESPISSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDT
NLTKLKFKEDDTRGILTPSDEFQFWIEQAHRGNKQISKERANYFKELFETIAREFYNLDS
LSLLEVVDLVETTQDVVDDVWRQTEHDHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWE
DPYYLVKESLKAGISICEQWVIVCNHLTGQVWQRYVPHPWKNEKYFPETLDKLGKRLEEV
LAIRTIHEKFLYFLPASEEKIICLTRVFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAP
AEQKIAGKLKNYISEIQDSPQQLLQAFLKYKELVKRPTISKELMLERETLLARLVDSIKD
FRLDFENRCRGIPGDASGPLSGKNLSEVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFR
CFHQSAKDLLDQLKLYEQEQFDDWSRDIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVH
YSDRLVILLREVRQLSALGFVIPAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQS
QRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRK
WHTTFCEKVVVLMNIDLLRQQQRWKDGLQELRTGLATVEAQGFQASDMHAWKQHWNHQLY
KALEHQYQMGLEALNENLPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFK
GVGEAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEK
HLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSL
KKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKN
RLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKF
KARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNF
SLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVE
EHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLL
RVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKD
WKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEP
IFGRGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQRS
LNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHIT
AMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLF
PSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILEL
KLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYE
YQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFN
CDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCEL
LGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEG
FKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANE
SHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEI
IPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMP
RYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNR
LLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQP
AEYRNNLENWIGDYFEKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIR
GLGGNLNMKSRLEFTKEVFHWARESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDF
SNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIA
TVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTL
VAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPE
REQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFF
TPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTS
VFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKG
LIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGA
VLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGE
VPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCE
SNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKS
FLLIHESCKAYGATPSQYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDEL
NRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKI
DDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSM
KSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVK
ANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSE
AAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYL
SAAPESLRKTCLEEWTKSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQS
RVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEP
VLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTT
TRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILEN
KDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINN
MYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALH
FVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALP
SLYQTLCFEDAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQVLRPDRLQSAMALFA
CKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVA
MGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVH
PNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAAC
QERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNY
FDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPS
FFGLPANIARSSQRMISSQVISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNS
NLIHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKL
ASALLNQKCPLAWQSKWEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELF
HPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSE
NQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERDRVVTNIDVPCGGNQDQ
WIQCGAALFLKNQ
Sequence of entity 2 (C), FASTA
>6RLB_2 WD repeat-containing protein 60 (chains C)
MEPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDP
DQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKD
REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGD
EDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDKKHREKSSTREKREKY
SKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKREFQNGEHRNR
GASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEET
DLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQ
RAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSR
TQALKQKMRSTKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQCNEDNV
ERDIQTEEIETREVWTQHPGESTVVSGGSEQRDTSDAVVMPKIDTPRLCSFLRAACQVMA
VLLEEDRLAAEPSWNLRAQDRALYFSDSSSQLNTSLPFLQNRKVSSLHTSRVQRQMVVSV
HDLPEKSFVPLLDSKYVLCVWDIWQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGS
VVVWDLREDSRLHYSVTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQS
FVLSPFSTQEEMSGLSFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVH
SALIQLGDSLSHKGNEFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVAPKLF
KPQQHGIRPVKVNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGL
QWSPTRPAVFLVQDDTSNIYIWDLLQSDLGPVAKQQVSPNRLVAMAAVGEPEKAGGSFLA
LVLARASGSIDIQHLKRRWAAPEVDECNRLRLLLQEALWPEGKLHK
Sequence of entity 3 (D), FASTA
>6RLB_3 WD repeat-containing protein 34 (chains D)
MATRAQPGPLSQAGSAGVAALATVGVASGPGPGRPGPLQDETLGVASVPSQWRAVQGIRW
ETKSCQTASIATASASAQARNHVDAQVQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVI
RELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVVACAY
GRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSG
EVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQG
IGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPL
KCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLY
SMLQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQ
DESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLSTEFTEQGPREAEDLDCLAAEVAAWSHP
QFEKGSAGSAAGSGAGWSHPQFEK
Sequence of entity 4 (E, F), FASTA
>6RLB_4 Cytoplasmic dynein 2 light intermediate chain 1 (chains E, F)
MPSETLWEIAKAEVEKRGINGSEGDGAEIAEKFVFFIGSKNGGKTTIILRCLDRDEPPKP
TLALEYTYGRRAKGHNTPKDIAHFWELGGGTSLLDLISIPITGDTLRTFSLVLVLDLSKP
NDLWPTMENLLQATKSHVDKVIMKLGKTNAKAVSEMRQKIWNNMPKDHPDHELIDPFPVP
LVIIGSKYDVFQDFESEKRKVICKTLRFVAHYYGASLMFTSKSEALLLKIRGVINQLAFG
IDKSKSICVDQNKPLFITAGLDSFGQIGSPPVPENDIGKLHAHSPMELWKKVYEKLFPPK
SINTLKDIKDPARDPQYAENEVDEMRIQKDLELEQYKRSSSKSWKQIELDS
Sequence of entity 5 (G, H), FASTA
>6RLB_5 Dynein light chain roadblock-type 1 (chains G, H)
MAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYASLMHSFILKARSTVRDI
DPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPTE
Sequence of entity 6 (I, J, K, L, M, N), FASTA
>6RLB_6 Dynein light chain 1, cytoplasmic (chains I, J, K, L, M, N)
MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGR
NFGSYVTHETKHFIYFYLGQVAILLFKSG
Primary citation
Structure of the dynein-2 complex and its assembly with intraflagellar transport trains. Toropova, K., Zalyte, R., Mukhopadhyay, A.G. et al. Nat Struct Mol Biol (2019) 26:823-829. DOI 10.1038/s41594-019-0286-y · PubMed
Other PDB entries of the same protein (UniProt E5BBQ0 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 3KZY 1.9 Å, Crystal structure of SNAP-tag
- 6Y8P 2.3 Å, Crystal structure of SNAP-tag labeled with a benzyl-tetramethylrhodamine fluorophore
- 8TK7 2.53 Å, Myxococcus xanthus EncA protein shell with compartmentalized SNAP-tag cargo protein
- 9Q2H 2.74 Å, Rad55-Rad57-SHU homologous recombination complex
- 9Q2I 3.0 Å, Rad55-Rad57-SHU homologous recombination complex
- 9Q2C 3.06 Å, Rad55-Rad57-SHU-Rad51 bound to ssDNA with AMP-PNP
- 9Q2F 3.06 Å, Rad55-Rad57-SHU-Rad51-Rad51 bound to ssDNA with AMP-PNP
- 8DD7 3.3 Å, The Cryo-EM structure of Drosophila Cryptochrome in complex with Timeless
- 9Q2E 3.44 Å, Rad55-Rad57-SHU bound to ssDNA
- 9Q2L 3.7 Å, Rad55-Rad57(E161Q)-SHU-3xRad51 bound to ssDNA with ATP
- 6RLA 3.9 Å, Structure of the dynein-2 complex; motor domains
- 6SC2 3.9 Å, Structure of the dynein-2 complex; IFT-train bound model
Browse structure collections
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