6RVU: Burkholderia Lethal Factor 1

Crystal structure of the Burkholderia Lethal Factor 1 (BLF1). Determined by X-ray diffraction at 0.99 Å resolution. Released 15 Jul 2020.

Method
X-ray diffraction
Resolution
0.99 Å
Organism
Burkholderia pseudomallei (strain K96243)
Chains
1
Atoms
2,116
Mol. weight
25.78 kDa
Released
15 Jul 2020

Explore 6RVU in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6RVU contains 9 α-helices and 19 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 9 helices, 19 β-strands

ElementResiduesLengthSheet
α-helix5-1511
β-strand20-2341
α-helix25-295
α-helix311
β-strand33-42101
β-strand45-4951
β-strand57-6481
β-strand71-7442
α-helix76-783
β-strand85-8841
β-strand9111
β-strand95-9952
β-strand104-10742
α-helix113-1208
α-helix124-1274
β-strand134-14292
α-helix147-1493
β-strand156-15832
α-helix160-1612
β-strand162-16432
β-strand16613
β-strand16913
β-strand171-180101
β-strand183-192101
β-strand195-19621
α-helix197-1993
β-strand200-20231
β-strand205-20952

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Lethal Factor 1 (BLF1)Aprotein231Burkholderia pseudomallei (strain K96243)Q63UP7 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>6RVU_1 Lethal Factor 1 (BLF1) (chains A)
MGSSHHHHHHSSGLVPRGSHMPNSLEAQIRQAMKTGSTLTIEFDQALNQKSPGTLNVFLH
PANGGVRIDLDSGNQGEPAKILWLPWKQGELQTLQPGSISTVDMLFFTYYLSGCKVFAGD
GGPVWHIDAPVEANQFWRRMSSDEWMEDWEVGTDRQVAYLHRAGQSDSLWNLSAYLEGAA
PSTYGRDNLGQAVVGGIVTGRQQMSLYQYATTSSGSSAWSPLTYTLQQRKQ

Primary citation

Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1. Mobbs, G.W., Aziz, A.A., Dix, S.R. et al. Commun Biol (2022) 5:272-272. DOI 10.1038/s42003-022-03186-2 · PubMed

Other PDB entries of the same protein (UniProt Q63UP7 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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