6TAX: Mouse RNF213 wild type protein

Mouse RNF213 wild type protein. Determined by electron microscopy at 3.2 Å resolution. Released 1 Jul 2020.

Method
Electron microscopy
Resolution
3.2 Å
Organism
Mus musculus
Chains
1
Atoms
35,235
Mol. weight
528.34 kDa
Ligands
ATP, MG, ZN
Released
1 Jul 2020

Explore 6TAX in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6TAX contains 241 α-helices and 87 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 241 helices, 87 β-strands

ElementResiduesLengthSheet
α-helix478-48811
α-helix497-51115
α-helix522-53918
α-helix593-6019
α-helix602-6043
α-helix609-6113
α-helix614-6174
α-helix629-6357
α-helix636-6394
α-helix644-65512
α-helix663-6664
α-helix668-6714
α-helix681-6822
α-helix689-6935
α-helix700-7023
α-helix712-7198
α-helix721-7255
α-helix729-7357
α-helix743-7486
α-helix751-7566
α-helix760-77112
α-helix781-80020
α-helix811-82616
α-helix836-84914
α-helix852-8543
α-helix865-88824
α-helix909-9179
α-helix930-9389
α-helix943-9508
α-helix963-98119
α-helix995-100915
α-helix1022-10309
α-helix1032-104312
α-helix1045-10484
α-helix1054-107118
β-strand107911
α-helix1080-10889
α-helix1090-110112
α-helix1114-114229
β-strand1149-115132
α-helix1155-11584
β-strand116611
α-helix1167-11704
α-helix1191-120212
α-helix1207-121711
β-strand1231-123332
α-helix1234-12374
α-helix1238-12425
α-helix1243-125614
α-helix1263-12697
α-helix1271-12733
α-helix1277-128812
α-helix1299-132830
α-helix1339-13457
α-helix1362-13676
α-helix1378-13869
α-helix1389-13979
α-helix1401-14033
α-helix1404-141411
α-helix1419-143921
α-helix1448-146316
α-helix1468-14769
α-helix1479-14868
α-helix1498-15069
β-strand1508-151143
α-helix1522-15254
β-strand1526-153053
β-strand1541-154443
α-helix1545-155612
α-helix1564-159330
β-strand1602-160653
β-strand1612-161653
β-strand1625-162733
α-helix1631-165929
α-helix1662-16654
α-helix1668-167811
α-helix1687-16904
α-helix1700-17089
α-helix1714-172512
α-helix1727-17304
α-helix1736-174914
α-helix1751-17533
α-helix1761-177414
β-strand178014
α-helix1782-17843
β-strand1792-179655
α-helix1799-18013
α-helix1803-18097
α-helix1817-18193
β-strand1824-182635
α-helix1833-184311
β-strand185114
β-strand1853-185755
α-helix1859-18613
α-helix1864-188017
β-strand1887-189265
α-helix1901-19044
α-helix1906-19083
β-strand190915
α-helix1918-192912
α-helix1938-19414
β-strand1948-195366
α-helix1960-197314
β-strand1982-198766
α-helix1994-20018
β-strand2015-202066
α-helix2028-20325
α-helix2033-20375
β-strand2040-204237
β-strand2048-205037
β-strand205318
β-strand205518
β-strand2056-206276
α-helix2081-20844
α-helix2085-20873
β-strand2090-209236
α-helix2117-21204
α-helix2123-213614
α-helix2155-216511
α-helix2173-219220
α-helix2195-22028
α-helix2208-222316
α-helix2251-22544
β-strand2266-226949
β-strand2276-227949
β-strand2282-2285410
β-strand2290-2294510
β-strand2307-2308210
α-helix2309-23179
α-helix2331-234111
α-helix2358-237316
β-strand2377-2380411
α-helix2388-239912
β-strand2407-2411511
α-helix2418-243922
β-strand2443-2448611
α-helix2456-24638
β-strand2467-2468212
β-strand2471-2472212
α-helix2473-24742
β-strand2479-2485711
β-strand2490113
α-helix2491-24922
α-helix2493-25008
β-strand2504114
β-strand2516115
β-strand2521115
α-helix2522-25243
β-strand2525113
α-helix2530-25334
β-strand2540-2541211
α-helix2551-256313
α-helix2572-258817
α-helix2601-261414
α-helix2618-263013
α-helix2643-26508
α-helix2651-26555
α-helix2661-26688
α-helix2674-26763
α-helix2679-269618
α-helix2698-26992
α-helix2707-272115
β-strand2726-2729416
α-helix2738-27469
β-strand2762-2768716
α-helix2776-279015
β-strand2798-2804716
α-helix2818-28203
α-helix2821-28244
β-strand2841-2846616
β-strand2848114
α-helix2852-28554
β-strand2859-2862416
α-helix2868-287912
α-helix2886-28894
α-helix2890-28923
α-helix2893-290614
α-helix2914-293118
α-helix2937-294711
α-helix2956-29605
α-helix2975-29839
β-strand3002-3006517
α-helix3011-30144
α-helix3015-30195
β-strand3026-3028317
α-helix3038-305518
β-strand3059-3061317
α-helix3072-30765
β-strand3080-3082318
β-strand3085-3092818
β-strand3095-3100618
β-strand3107-3112617
α-helix3113-31197
α-helix3125-31273
β-strand3130-3132317
α-helix3141-315818
β-strand3160119
α-helix3170-31723
α-helix3173-31764
β-strand3177120
α-helix3184-319613
α-helix3205-321814
β-strand3221120
α-helix3223-32286
α-helix3229-32313
β-strand3232119
α-helix3237-32448
α-helix3245-32495
α-helix3255-32628
β-strand3272-3279821
α-helix3282-32843
α-helix3288-32947
β-strand3304-3307421
α-helix3308-33103
α-helix3314-332512
β-strand3332-3339821
α-helix3349-336416
β-strand3371-3378821
β-strand3397-3400421
α-helix3406-34072
β-strand3410122
α-helix3414-34196
α-helix3422-34254
β-strand3475122
α-helix3477-348913
β-strand3493123
α-helix3502-351110
α-helix3518-353821
α-helix3549-35546
α-helix3557-35637
α-helix3566-358924
α-helix3596-35994
α-helix3605-361410
α-helix36391
β-strand3640123
α-helix36411
α-helix3658-367518
α-helix3681-369111
α-helix3693-36986
α-helix3703-372119
α-helix3728-374518
α-helix3763-378321
α-helix3788-379912
α-helix3808-382316
α-helix3829-383810
α-helix3840-38467
α-helix3857-387923
α-helix3880-38845
α-helix3885-38895
α-helix3895-390915
α-helix3918-394023
β-strand3958-3959224
β-strand3965-3966224
α-helix3968-39758
α-helix3987-39893
β-strand3996124
α-helix4000-402526
α-helix4036-40449
β-strand4047125
β-strand4064125
β-strand4080126
α-helix4083-40886
α-helix4093-40953
α-helix4097-411014
α-helix4117-413721
α-helix4143-415513
α-helix4172-419726
α-helix4205-421814
α-helix4223-423513
α-helix4238-42447
α-helix4252-42543
α-helix4257-42615
α-helix4272-42754
α-helix4280-429213
α-helix4297-43037
α-helix4310-433021
α-helix4343-435210
α-helix4359-436911
α-helix4385-440218
α-helix4406-44083
α-helix4409-44168
α-helix4418-44214
β-strand4425127
β-strand4502127
α-helix4523-454321
α-helix4545-45517
α-helix4560-457718
α-helix4582-459514
α-helix4614-463219
α-helix4639-46479
α-helix4656-46594
α-helix4666-46683
α-helix4692-470110
α-helix4709-47168
α-helix4718-47214
α-helix4724-47263
α-helix4727-474014
β-strand4751128
α-helix4752-47565
α-helix4762-478221
α-helix4786-47894
β-strand4808128
α-helix4821-484424
α-helix4860-48623
α-helix4868-48725
α-helix4873-48775
β-strand4880-4883429
β-strand4884126
β-strand4891-4894429
α-helix4896-49049
α-helix4931-494010
α-helix4948-49569
α-helix4961-497919
β-strand4988130
α-helix4989-49902
α-helix4991-49966
α-helix5004-50107
β-strand5014130
α-helix5015-50173
α-helix5018-503518
α-helix5046-50483
β-strand5049131
α-helix5054-506512
α-helix5069-508315
α-helix5099-51068
α-helix5115-51206
β-strand5130131
α-helix5132-514817

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
RNF213,E3 ubiquitin-protein ligase RNF213,E3 ubiquitin-protein ligase RNF213Aprotein4638Mus musculusE9Q555
Sequence of entity 1 (A), FASTA
>6TAX_1 RNF213,E3 ubiquitin-protein ligase RNF213,E3 ubiquitin-protein ligase RNF213 (chains A)
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXKLTLGLSILFMVEAAEFTVPKKDLDSLCYLLIPSAGSPEALHSDLSPVLRIRQ
RWRIYLTNLCLRCIDERCDRWLGILPLLHTCMQKSPPKKNSKSQPEDTWAGLEGISFSEF
RDKAPTRSQPLQFMQSKMALLRVDEYLFRSWLSVVPLESLSSYLENSIDYLSDVPVRVLD
CLQGISYRLPGLRKISNQNMKKDVENVFKMLMHLVDIYQHRIFGENLLQIYLTECLTLHE
TVCNITANHQFFEIPALSAELICKLLELSPPGHTDEGLPEKSYEDLVTSTLQEALATTRN
WLRSLFKSRMLSISSAYVRLTYSEEMAVWRRLVEIGFPEKHGWKGSLLGDMEGRLKQEPP
RLQISFFCSSQCRDGGLHDSVSRSFEKCVIEAVSSACQSQTSVLEGLSCQDLQKFGTLLS
AVITKSWPVHNGEPVFDVDEIFKYLLKWPDVRQLFELCGTNEKIIDNITEEGRQLMATAE
SVFQKVAGELENGTIVVGQLELILEHQSQFLDIWNLNRRRLPSQEKACDVRSLLKRRRDD
LLFLKQEKRYVESLLRQLGRVKHLVQVDFGNIEIIHSQDLSNKKLNEAVIKLPNSSSYKR
ETHYCLSPDIREMASKLDSLKDSHIFQDFWQETAESLNTLDKDPRELKVSLPEVLEYLYN
PCYDNFYTLYENLKSGKITFAEVDAIFKDFVDKYDELKNDLKFMCTMNPQDQKGWISERV
GQIKEYHTLHQAVSSAKVILQVRRALGVTGDFSVLNPLLNFADSFEDFGNEKLDQISPQF
IKAKQLLQDISEPRQRCLEELARQTELVAWLHKALEDINELKVFVDLASISAGENDIDVD
RVACFHDAVQGYASLLYKMDERTNFSDFMNHLQELWRALDNDQHLPDKLKDSARNLEWLK
TVKESHGSVELSSLSLATAINSRGVYVIEAPKDGQKISPDTVLRLLLPDGHGYPEALRTY
STEELKELLNKLMLMSGKKDHNSNTEVEKFSEVFSNMQRLVHVFIKLHCAGNMLFRTWTA
KVYCCPDGGIFMNFGLELLSQLTEKGDVIQLLGALCRQMEDFLDNWKTVVAQKRAEHFYL
NFYTAEQLVYLSSELRKPRPSEAALMMLSFIKGKCTVQDLVQATSACESKADRYCLREVM
KKLPQQLLSEPSLMGKLQVIMMQSLVYMSAFLPHCLDLDALGRCLAHLATMGGTPVERPL
PKGLQAGQPNLILCGHSEVLPAALAIYMQAPRQPLPTFDEVLLCTPATTIEEVELLLRRC
LTSGSQGHKVYSLLFADQLSYEVGCQAEEFFQSLCTRAHREDYQLVILCDAAREHCYIPS
TFSQYKVPLVPQAPLPNIQAYLQSHYQVPKRLLSAATVFRDGLCVGIVTSERAGVGKSLY
VNTLHTKLKAKLRDETVPLKIIRLTEPHLDENQVLSALLPFLKEKYQKMPVIFHIDISTS
VQTGIPIFLFKLLILQYLMDINGKIWRRSPGHLYLVEIPQGLSVQPKRSSKLNARAPLFK
FLDLFPKVTCRPPKEVIDMELTPERSHTDPAMDPVEFCSEAFQRPYQYLKRFHQQQNLDT
FQYEKGSVEGSPEECLQHFLIYCGLINPSWSELRNFAWFLNCQLKDCEASIFCKSAFTGD
TLRGFKNFVVTFMILMARDFATPTLHTSDQSPGRQSVTIGEVVEEDLAPFSLRKRWESEP
HPYVFFNGDHMTMTFIGFHLETNNNGYVDAINPSNGKVIKKDVMTKELFDGLRLQRVPFN
IDFDNLPRYEKLERLCLALGIEWPIDPDETYELTTDNMLKILAIEMRFRCGIPVIIMGET
GCGKTRLIKFLSDLKRGSVEAETMKLVKVHGGTTPSMIYSKVKEAERTAFSNKAQHKLDT
ILFFDEANTTEAVSCIKEILCDRTVDGEHLHEDSGLHIIAACNPYRKHSQEMILRLESAG
LGYRVSAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLNDSAEKLYIQQIVQRLV
DSVSVNPSETCVIADVLSASQMFMRKRENECGFVSLRDVERCVKVFRWFHDHSDMLLKEL
DKFLHESSDSTHTFERDPVLWSLVMAIGVCYHASLEEKASYRTAIARCFPKPYNSSRAIL
DEVTHVQDLFLRGAPIRTNIARNLALKENVFMMVICIELKIPLFLVGKPGSSKSLAKIIV
ADAMQGQAAFSELFRCLKQVHLVSFQCSPHSTPQGIISTFKQCARFQQGKDLGQYVSVVV
LDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPYKKVGFVGISNWALDPAKMNRGIFVSR
GSPNEKELIESAEGICSSDRLVQDKIRGYFAPFAKAYETVCQKQDKEFFGLRDYYSLIKM
VFAKAKASKRGLSPQDITHAVLRNFSGKDNIQALSIFTASLPEARYKEEVSTVELIKQNI
YPGPQASSRGLDGAESRYLLVLTRNYVALQILQQTFFEGQQPEIIFGSSFPQDQEYTQIC
RNINRVKICMETGKMVVLLNLQNLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHT
AFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQPWQKSIVQELQQWAHEFADVKAD
QFIARHKYSPADVFIGYHSDACASVVLQAVERQGCRDLTEELYRKVSEEARSILLDCATP
DAVVRLSGSSLGSFTAKQLSQEYYYAQQHNSFVDFLQAHLRMTHHECRAVFTEITTFSRL
LTGNDCDVLASELRGLASKPVVLSLQQYDTEYSFLKDVRSWLTNPGKRKVLVIQADFDDG
TRSAQLVASAKYTAINEINKTQGTKDFVFVYFVTKLSRMGSGTSYVGFHGGLWRSVHIDD
LRRSTIMASDVTKLQNVTISQLFKPEDKPEQEEMEIETSQSKELAEEQMEVEDSEEMKKA
SDPRSCDCSQFLDTTRLVQSCVQGAVGMLRDQNESCARNMRRVTILLDLLNEDNTRNASF
LRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILA
SMIAHIDRDGNLELLAQPDSPAWVQDLWMFIYSDIKFLNISLVLNNTRSNSEMSFILVQS
HMNLLKDAYNAVPFSWRIRDYLEELWVQAQYITDTEGLSKKFVEIFQKTPLGVFLAQFPV
AQQQKLLQSYLKDFLLLTMKVSSREELMFLQMALWSCLRELQEASGTPDETYKFPLSLPW
VHLAFQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHSLAGCEMTLDAFAAMACAEMLKGD
LLKPSPKAWLQLVKNLSTPLELVCSEGYLCDSGSMTRSVIQEVRALWNRIFSIALFVEHV
LLGTESHIPELSPLVTTYVSLLDKCLEEDSNLKTCRPFVAVMTTLCDCKDKASKKFSRFG
IQPCFICHGDAQDPVCLPCDHVYCLRCIQTWLIPGQMMCPYCLTDLPDKFSPTVSQDHRK
AIEKHAQFRHMCNSFFVDLVSTMCFKDNTPPEKSVIDTLLSLLFVQKELLRDASQKHREH
TKSLSPFDDVVDQTPVIRSVLLKLLLKYSFHEVKDYIQNYLTQLEKKAFLTEDKTELYLL
FISCLEDSVHQKTSAGCRNLEQVLREEGHFLRTYSPGLQGQEPVRIASVEYLQEVARVRL
CLDLAADFLSELQEGSELAEDKRRFLKHVEEFCTRVNNDWHRVYLVRKLSSQRGMEFVQS
FSKQGHPCQWVFPRKVIAQQKDHVSLMDRYLVHGNEYKAVRDATAKAVLECKTLDIGNAL
MACRSPKPQQTAYLLLALYTEVAALYRSPNGSLHPEAKQLEAVNKFIKESKILSDPNIRC
FARSLVDNTLPLLKIRSANSILKGTVTEMAVHVATILLCGHNQILKPLRNLAFYPVNMAN
AFLPTMPEDLLVHARTWRGLENVTWYTCPRGHPCSVGECGRPMQESTCLDCGLPVGGLNH
TPHEGFSAIRNNEDRTQTGHVLGSPQSSGVAEVSDRGQSPVVFILTRLLTHLAMLVGATH
NPQALTVIIKPWVQDPQGFLQQHIQRDLEQLTKMLGRSADETIHVVHLILSSLLRVQSHG
VLNFNAELSTKGCRNNWEKHFETLLLRELKHLDKNLPAINALISQDERISSNPVTKIIYG
DPATFLPHLPQKSIIHCSKIWSCRRKITVEYLQHIVEQKNGKETVPVLWHFLQKEAELRL
VKFLPEILALQRDLVKQFQNVSRVEYSSIRGFIHSHSSDGLRKLLHDRITIFLSTWNALR
RSLETNGEIKLPKDYCCSDLDLDAEFEVILPRRQGLGLCGTALVSYLISLHNNMVYTVQK
FSNEDNSYSVDISEVADLHVISYEVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQI
SSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNKMAQSSLPNLAISTISGQLQSYSD
ACEALSIIEITLGFLSTAGGDPGMDLNVYIEEVLRMCDQTAQVLKAFSRCQLRHIIALWQ
FLSAHKSEQRLRLNKELFREIDVQYKEELSTQHQRLLGTFLNEAGLDAFLLELHEMIVLK
LKGPRAANSFNPNWSLKDTLVSYMETKDSDILSEVESQFPEEILMSSCISVWKIAATRKW
DRQSRGGGHHHHHHHHHH

Ligands and cofactors

IDNameFormulaCopies
ATPAdenosine-5'-triphosphateC10 H16 N5 O13 P31
MGMagnesium ionMg1
ZNZinc ionZn2

Primary citation

Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism. Ahel, J., Lehner, A., Vogel, A. et al. Elife (2020) 9. DOI 10.7554/eLife.56185 · PubMed

Other PDB entries of the same protein (UniProt E9Q555), best resolution first:

Browse structure collections

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