6TFV: Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18b

Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18b. Determined by x-ray diffraction at 1.5 Å resolution. Released 2020.

Composition

This structure contains 4,649 atoms across 1 protein chain. Molecular weight: 77.65 kDa.

Primary citation

Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.. Lategahn, J., Hardick, J., Grabe, T. et al., J.Med.Chem. (2020).

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Source: RCSB Protein Data Bank