Vsv G_440. Determined by X-ray diffraction at 2.07 Å resolution. Released 2 Sept 2020.
Explore 6TIT in 3D Show helices and sheets RCSB PDB PDBe
6TIT contains 18 α-helices and 38 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 2-7 | 6 | 1 |
| β-strand | 15-16 | 2 | 1 |
| α-helix | 17-18 | 2 | |
| α-helix | 25-28 | 4 | |
| β-strand | 37-45 | 9 | 2 |
| α-helix | 48-51 | 4 | |
| β-strand | 54 | 1 | 3 |
| β-strand | 56-68 | 13 | 4 |
| β-strand | 78-84 | 7 | 4 |
| α-helix | 89-101 | 13 | |
| β-strand | 122-131 | 10 | 4 |
| β-strand | 134 | 1 | 3 |
| β-strand | 135-136 | 2 | 5 |
| β-strand | 143-144 | 2 | 5 |
| β-strand | 148 | 1 | 6 |
| α-helix | 149-151 | 3 | |
| β-strand | 152-153 | 2 | 5 |
| β-strand | 157-159 | 3 | 4 |
| β-strand | 160 | 1 | 6 |
| β-strand | 166-169 | 4 | 4 |
| β-strand | 182-190 | 9 | 2 |
| α-helix | 195-197 | 3 | |
| β-strand | 198 | 1 | 7 |
| β-strand | 200 | 1 | 7 |
| β-strand | 203-206 | 4 | 2 |
| β-strand | 213-214 | 2 | 2 |
| β-strand | 219-223 | 5 | 8 |
| β-strand | 226-230 | 5 | 8 |
| β-strand | 236-237 | 2 | 8 |
| β-strand | 238-239 | 2 | 2 |
| α-helix | 242-248 | 7 | |
| α-helix | 250-251 | 2 | |
| β-strand | 252 | 1 | 8 |
| α-helix | 253-254 | 2 | |
| β-strand | 263 | 1 | 1 |
| α-helix | 269-271 | 3 | |
| α-helix | 274-292 | 19 | |
| α-helix | 299-303 | 5 | |
| β-strand | 311-319 | 9 | 1 |
| β-strand | 322-335 | 14 | 1 |
| β-strand | 339-340 | 2 | 9 |
| β-strand | 344-347 | 4 | 1 |
| β-strand | 353-355 | 3 | 1 |
| β-strand | 361-363 | 3 | 9 |
| β-strand | 366-368 | 3 | 9 |
| α-helix | 370-372 | 3 | |
| β-strand | 374-376 | 3 | 9 |
| β-strand | 379-381 | 3 | 9 |
| α-helix | 383-386 | 4 | |
| α-helix | 392-393 | 2 | |
| α-helix | 394-397 | 4 | |
| β-strand | 403 | 1 | 1 |
| α-helix | 410-415 | 6 | |
| α-helix | 421-422 | 2 | |
| β-strand | 423-425 | 3 | 4 |
| β-strand | 428-431 | 4 | 4 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Glycoprotein | A | protein | 432 | Recombinant vesicular stomatitis Indiana virus rVSV-G/GFP | B7UCZ5 (AlphaFold model) |
>6TIT_1 Glycoprotein (chains A) KFTIVFPHNQKGNWKNVPSNYHYCPSSSDLNWHNDLIGTALQVKMPKSHKAIQADGWMCH ASKWVTTCDFRWYGPKYITHSIRSFTPSVEQCKESIEQTKQGTWLNPGFPPQSCGYATVT DAEAVIVQVTPHHVLVDEYTGEWVDSQFINGKCSNYICPTVHNSTTWHSDYKVKGLCDSN LISMDITFFSEDGELSSLGKEGTGFRSNYFAYETGGKACKMQYCKHWGVRLPSGVWFEMA DKDLFAAARFPECPEGSSISAPSQTSVDVSLIQDVERILDYSLCQETWSKIRAGLPISPV DLSYLAPKNPGTGPAFTIINGTLKYFETRYIRVDIAAPILSRMVGMISGTTTERELWDDW APYEDVEIGPNGVLRTSSGYKFPLYMIGHGMLDSDLHLSSKAQVFEHPHIQDAASQLPDD ESLFFGDTGLSK
Water and common crystallization additives (GOL, PEG, ACT) are not listed.
Identification of a pH-Sensitive Switch in VSV-G and a Crystal Structure of the G Pre-fusion State Highlight the VSV-G Structural Transition Pathway. Beilstein, F., Abou Hamdan, A., Raux, H. et al. Cell Rep (2020) 32:108042-108042. DOI 10.1016/j.celrep.2020.108042 · PubMed
Other PDB entries of the same protein (UniProt B7UCZ5 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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