6X0L: Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin

Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin. Determined by electron microscopy at 3.9 Å resolution. Released 2020.

Composition

This structure contains 8,037 atoms across 2 protein chains and 2 nucleic acid chains. Molecular weight: 380.96 kDa.

Primary citation

Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.. Bilokapic, S., Suskiewicz, M.J., Ahel, I. et al., Nature (2020).

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Source: RCSB Protein Data Bank