6Y5Q: Human 17S U2 snRNP
human 17S U2 snRNP. Determined by electron microscopy at 7.1 Å resolution. Released 17 Jun 2020.
- Method
- Electron microscopy
- Resolution
- 7.1 Å
- Organism
- Homo sapiens
- Chains
- 22
- Atoms
- 22,867
- Mol. weight
- 1073.21 kDa
- Released
- 17 Jun 2020
Explore 6Y5Q in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6Y5Q contains 178 α-helices and 239 β-strands across 21 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 6: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 161-174 | 14 | |
| α-helix | 186-189 | 4 | |
| α-helix | 205-217 | 13 | |
| α-helix | 221-225 | 5 | |
| α-helix | 236-271 | 36 | |
Chain 7: 2 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 105-108 | 4 | |
| α-helix | 115-117 | 3 | |
| β-strand | 118-121 | 4 | 49 |
| β-strand | 134-137 | 4 | 49 |
| β-strand | 148-153 | 6 | 50 |
| β-strand | 167-172 | 6 | 50 |
| β-strand | 179-183 | 5 | 50 |
| β-strand | 197-200 | 4 | 49 |
| β-strand | 205-208 | 4 | 49 |
Chain 8: 11 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 464-467 | 4 | |
| α-helix | 472-474 | 3 | |
| α-helix | 478-481 | 4 | |
| α-helix | 485-492 | 8 | |
| α-helix | 523-525 | 3 | |
| α-helix | 526-529 | 4 | |
| α-helix | 572-575 | 4 | |
| α-helix | 579-582 | 4 | |
| β-strand | 608 | 1 | 5 |
| α-helix | 611-617 | 7 | |
| α-helix | 619-622 | 4 | |
| α-helix | 633-639 | 7 | |
| β-strand | 648-649 | 2 | 6 |
| β-strand | 651 | 1 | 7 |
| β-strand | 655 | 1 | 7 |
| β-strand | 683 | 1 | 5 |
| β-strand | 686 | 1 | 5 |
| β-strand | 689-690 | 2 | 6 |
Chain 9: 21 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-27 | 22 | |
| α-helix | 33-58 | 26 | |
| α-helix | 64-71 | 8 | |
| α-helix | 78-87 | 10 | |
| α-helix | 103-108 | 6 | |
| α-helix | 126-128 | 3 | |
| α-helix | 143-153 | 11 | |
| α-helix | 160-167 | 8 | |
| α-helix | 182-200 | 19 | |
| α-helix | 206-219 | 14 | |
| α-helix | 221-223 | 3 | |
| β-strand | 227 | 1 | 51 |
| β-strand | 282-283 | 2 | 51 |
| β-strand | 290-291 | 2 | 51 |
| α-helix | 294-301 | 8 | |
| α-helix | 304-307 | 4 | |
| α-helix | 318-333 | 16 | |
| α-helix | 335-350 | 16 | |
| α-helix | 353-361 | 9 | |
| α-helix | 394-400 | 7 | |
| β-strand | 406-408 | 3 | 52 |
| β-strand | 414-416 | 3 | 52 |
| α-helix | 419-424 | 6 | |
| α-helix | 429-438 | 10 | |
| α-helix | 453-461 | 9 | |
| α-helix | 491-497 | 7 | |
Chain a: 7 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-10 | 5 | |
| β-strand | 13-16 | 4 | 43 |
| β-strand | 22-25 | 4 | 43 |
| α-helix | 37-39 | 3 | |
| β-strand | 46-48 | 3 | 43 |
| β-strand | 56-57 | 2 | 44 |
| β-strand | 68-70 | 3 | 43 |
| β-strand | 78-79 | 2 | 44 |
| α-helix | 83-86 | 4 | |
| β-strand | 92-94 | 3 | 43 |
| α-helix | 103-106 | 4 | |
| α-helix | 108-111 | 4 | |
| β-strand | 117-119 | 3 | 43 |
| α-helix | 131-138 | 8 | |
| β-strand | 144-145 | 2 | 43 |
| β-strand | 149 | 1 | 43 |
| α-helix | 152-160 | 9 | |
Chain b: 5 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 11-15 | 5 | 45 |
| α-helix | 23-34 | 12 | |
| β-strand | 40-45 | 6 | 45 |
| β-strand | 55-59 | 5 | 45 |
| α-helix | 62-71 | 10 | |
| β-strand | 76-77 | 2 | 46 |
| β-strand | 80-81 | 2 | 46 |
| β-strand | 83-86 | 4 | 45 |
| α-helix | 92-98 | 7 | |
| β-strand | 152-156 | 5 | 47 |
| α-helix | 164-171 | 8 | |
| β-strand | 177-181 | 5 | 47 |
| β-strand | 189-194 | 6 | 47 |
| α-helix | 197-206 | 10 | |
| β-strand | 219-222 | 4 | 47 |
Chain h: 2 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 20-26 | 7 | |
| α-helix | 29-37 | 9 | |
| β-strand | 41-46 | 6 | 59 |
| β-strand | 51-58 | 8 | 59 |
| β-strand | 65-76 | 12 | 59 |
| β-strand | 90-101 | 12 | 59 |
| β-strand | 106-111 | 6 | 59 |
Chain i: 1 helix, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-13 | 7 | |
| β-strand | 18-23 | 6 | 59 |
| β-strand | 27-36 | 10 | 59 |
| β-strand | 42-51 | 10 | 59 |
| β-strand | 54-64 | 11 | 59 |
| β-strand | 69-74 | 6 | 59 |
13 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| PHD finger-like domain-containing protein 5A | y | protein | 110 | Homo sapiens | Q7RTV0 (AlphaFold model) |
| Splicing factor 3B subunit 5 | x | protein | 86 | Homo sapiens | Q9BWJ5 (AlphaFold model) |
| Splicing factor 3B subunit 2 | 8 | protein | 895 | Homo sapiens | Q13435 (AlphaFold model) |
| Splicing factor 3B subunit 3 | v | protein | 1217 | Homo sapiens | Q15393 (AlphaFold model) |
| Splicing factor 3B subunit 1 | u | protein | 1304 | Homo sapiens | O75533 |
| Probable ATP-dependent RNA helicase DDX46 | p | protein | 1031 | Homo sapiens | Q7L014 |
| U2 small nuclear ribonucleoprotein A' | a | protein | 255 | Homo sapiens | P09661 |
| U2 small nuclear ribonucleoprotein B'' | b | protein | 225 | Homo sapiens | P08579 |
| Splicing factor 3B subunit 6 | z | protein | 125 | Homo sapiens | Q9Y3B4 |
| Splicing factor 3A subunit 1 | 6 | protein | 793 | Homo sapiens | Q15459 |
| Splicing factor 3A subunit 2 | 7 | protein | 464 | Homo sapiens | Q15428 |
| Splicing factor 3A subunit 3 | 9 | protein | 501 | Homo sapiens | Q12874 |
10 more molecules are not listed.
Sequence of entity 1 (y), FASTA
>6Y5Q_1 PHD finger-like domain-containing protein 5A (chains y)
MAKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVI
CGGPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYERKKYGFKKR
Sequence of entity 2 (x), FASTA
>6Y5Q_2 Splicing factor 3B subunit 5 (chains x)
MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENES
KARVRFNLMEKMLQPCGPPADKPEEN
Sequence of entity 3 (8), FASTA
>6Y5Q_3 Splicing factor 3B subunit 2 (chains 8)
MATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGNREELVERLQSYTRQ
TGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFP
MAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQ
QKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMG
APVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDA
RSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRGS
DSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAAPK
KKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDV
TAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREAL
QEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETR
LKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPES
CSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSE
EEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSET
PQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAM
TQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF
Sequence of entity 4 (v), FASTA
>6Y5Q_4 Splicing factor 3B subunit 3 (chains v)
MFLYNLTLQRATGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFG
VIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQF
LAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENP
MFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPG
GSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFF
FLAQTEQGDIFKITLETDEDMVTEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQ
IAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDT
PQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHIEDEFDAYIIVSFVN
ATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVNEWKTPG
KKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQ
RSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGTEKQDELGERGSI
GFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSW
LSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFP
LQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAA
AFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTG
EDWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVL
IGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQ
LIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRG
LLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDF
FQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRT
PPEVSKKLEDIRTRYAF
Sequence of entity 5 (u), FASTA
>6Y5Q_5 Splicing factor 3B subunit 1 (chains u)
MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
KHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGE
LKVVNGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAK
GSETPGATPGSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTE
RDTPGHGSGWAETPRTDRGGDSIGETPTPGASKRKSRWDETPASQMGGSTPVLTPGKTPI
GTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAG
YVPIRTPARKLTATPTPLGGMTGFHMQTEDRTMKSVNDQPSGNLPFLKPDDIQYFDKLLV
DVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLM
SPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNL
AKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQA
RHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYG
IESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP
DEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVEL
ANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAF
QEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAV
VMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRL
TPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNT
FGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPE
LNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVY
GFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARK
VRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL
Sequence of entity 6 (p), FASTA
>6Y5Q_6 Probable ATP-dependent RNA helicase DDX46 (chains p)
MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS
RSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS
KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME
NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVK
KFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEE
VDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGI
TVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGS
GKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVY
GGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE
PQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVI
EEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDS
IINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAY
TFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKF
DETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPA
PTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQL
AEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISE
YSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSY
QPTNKGRYKVL
Sequence of entity 7 (a), FASTA
>6Y5Q_7 U2 small nuclear ribonucleoprotein A' (chains a)
MVKLTAELIEQAAQYTNAVRDRELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGF
PLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGDLDPLASLKSLTYLSI
LRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDIARRSKT
FNPGAGLPTDKKKGGPSPGDVEAIKNAIANASTLAEVERLKGLLQSGQIPGRERRSGPTD
DGEEEMEEDTVTNGS
Sequence of entity 8 (b), FASTA
>6Y5Q_8 U2 small nuclear ribonucleoprotein B'' (chains b)
MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELG
SSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTT
NKKPGQGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEV
RLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK
Sequence of entity 9 (z), FASTA
>6Y5Q_9 Splicing factor 3B subunit 6 (chains z)
MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTA
YVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGIN
TDPPK
Sequence of entity 10 (6), FASTA
>6Y5Q_10 Splicing factor 3A subunit 1 (chains 6)
MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV
ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQ
QQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ
FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVL
DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT
PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD
DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI
PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE
ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD
TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP
PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP
VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW
KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV
IHLALKERGGRKK
Sequence of entity 11 (7), FASTA
>6Y5Q_11 Splicing factor 3A subunit 2 (chains 7)
MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCL
TLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAPAQPAPEKVKVEVKKFVKIGRPGYKVT
KQRDSEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIA
FKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNG
LPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASG
VHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP
APGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPG
VHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN
Sequence of entity 12 (9), FASTA
>6Y5Q_12 Splicing factor 3A subunit 3 (chains 9)
METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDL
YDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENP
SEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKERKNA
EYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWPKETSSALTHA
GAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSL
FAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEEREEEE
EEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPK
AFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASERWQPDTEEEYE
DSSGNVVNKKTYEDLKRQGLL
Primary citation
Molecular architecture of the human 17S U2 snRNP. Zhang, Z., Will, C.L., Bertram, K. et al. Nature (2020) 583:310-313. DOI 10.1038/s41586-020-2344-3 · PubMed
Other PDB entries of the same protein (UniProt Q7RTV0 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 5SYB 1.82 Å, Crystal structure of human PHF5A
- 7Q4O 2.1 Å, Substrate-bound A-like U2 snRNP
- 7Q4P 2.15 Å, U2 snRNP after ATP-dependent remodelling
- 7Q3L 2.21 Å, Human 17S U2 snRNP 5' domain
- 7B9C 2.4 Å, Structure of a minimal SF3B core in complex with spliceostatin A (form I)
- 7EVO 2.5 Å, The cryo-EM structure of the human 17S U2 snRNP
- 7EVN 2.6 Å, The cryo-EM structure of the DDX42-SF3b complex
- 8H6L 2.6 Å, Cryo-EM structure of human exon-defined spliceosome in the early B state.
- 8H6K 2.7 Å, Cryo-EM structure of human exon-defined spliceosome in the mature B state.
- 8HK1 2.7 Å, The cryo-EM structure of human pre-17S U2 snRNP
- 7DVQ 2.89 Å, Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)
- 7B0I 3.0 Å, Structure of a minimal SF3B core in complex with spliceostatin A (form II)
Browse structure collections
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