7ABH: Human pre-Bact-2 spliceosome

Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion). Determined by electron microscopy at 4.5 Å resolution. Released 9 Dec 2020.

Method: Electron microscopy
Resolution: 4.5 Å
Organisms: Homo sapiens, synthetic construct
Chains: 16
Atoms: 17,922
Mol. weight: 1029.67 kDa
Released: 9 Dec 2020

Explore 7ABH in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7ABH contains 139 α-helices and 150 β-strands across 14 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 0: 2 helices, 12 β-strands

Element	Residues	Length	Sheet
α-helix	231-236	6
β-strand	238	1	42
β-strand	243	1	42
α-helix	247-249	3
β-strand	261	1	43
β-strand	264	1	44
β-strand	273	1	43
β-strand	283	1	45
β-strand	292	1	45
β-strand	304	1	46
β-strand	307-314	8	47
β-strand	320-327	8	47
β-strand	330	1	46
β-strand	368	1	44

Chain 1: 5 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	5-19	15
α-helix	24-26	3
β-strand	37-41	5	48
α-helix	49-56	8
α-helix	57-59	3
β-strand	62-67	6	48
β-strand	80-84	5	48
α-helix	87-96	10
β-strand	108-111	4	48

Chain 4: 5 helices, 2 β-strands

Element	Residues	Length	Sheet
α-helix	394-399	6
β-strand	406-408	3	8
β-strand	414-416	3	8
α-helix	419-426	8
α-helix	429-438	10
α-helix	452-461	10
α-helix	489-497	9

Chain 7: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	148-178	31

Chain E: 20 helices, 99 β-strands

Element	Residues	Length	Sheet
β-strand	3-9	7	12
β-strand	16-20	5	13
β-strand	29-33	5	13
β-strand	37-41	5	13
β-strand	52-57	6	13
β-strand	62-68	7	14
β-strand	77-82	6	14
β-strand	86-91	6	14
β-strand	100-106	7	14
β-strand	120-123	4	15
β-strand	129-133	5	15
β-strand	136	1	16
β-strand	139-143	5	15
β-strand	144-145	2	17
β-strand	153-154	2	17
α-helix	156-157	2
β-strand	158-159	2	15
β-strand	165-172	8	16
α-helix	173-174	2
β-strand	181-188	8	16
α-helix	192-194	3
β-strand	207-214	8	16
β-strand	219-227	9	16
β-strand	232-238	7	18
α-helix	239	1
β-strand	247-252	6	18
β-strand	255-258	4	18
α-helix	264-266	3
β-strand	267-269	3	18
β-strand	273-274	2	19
β-strand	289-294	6	20
β-strand	299-304	6	20
β-strand	309-317	9	20
β-strand	322-332	11	20
β-strand	336-342	7	21
β-strand	346-351	6	21
β-strand	357-361	5	21
β-strand	372-374	3	20
β-strand	386-387	2	19
β-strand	395-399	5	21
β-strand	407-413	7	22
β-strand	422-427	6	22
α-helix	430-432	3
β-strand	434-438	5	22
β-strand	439	1	23
β-strand	442	1	24
β-strand	445-450	6	25
β-strand	458-463	6	26
β-strand	471-477	7	26
β-strand	482-486	5	26
β-strand	493-494	2	26
β-strand	507-510	4	27
β-strand	516-520	5	27
β-strand	523-527	5	27
β-strand	533-537	5	27
β-strand	544-549	6	28
β-strand	553-558	6	28
α-helix	559-561	3
β-strand	562	1	29
β-strand	563-568	6	28
β-strand	574-576	3	28
α-helix	577	1
α-helix	581	1
β-strand	582	1	29
α-helix	583	1
β-strand	587-592	6	30
α-helix	593-595	3
β-strand	604-609	6	30
β-strand	613-618	6	30
β-strand	626-632	7	30
β-strand	637-644	8	31
β-strand	663-669	7	31
β-strand	674-678	5	31
β-strand	687-689	3	31
β-strand	700-706	7	32
β-strand	709-715	7	32
β-strand	721-724	4	32
β-strand	729-732	4	32
β-strand	734	1	24
β-strand	741-745	5	25
β-strand	753-758	6	25
β-strand	761-766	6	25
β-strand	775	1	23
α-helix	784	1
β-strand	785-790	6	33
β-strand	797-804	8	33
α-helix	809-824	16
α-helix	839-844	6
β-strand	862-869	8	33
β-strand	876-881	6	33
β-strand	886-895	10	34
β-strand	903-911	9	34
β-strand	922-928	7	34
β-strand	942-945	4	34
β-strand	949-955	7	35
β-strand	958-963	6	35
β-strand	966-971	6	35
β-strand	978-983	6	35
β-strand	990-995	6	36
β-strand	999-1004	6	36
β-strand	1009-1015	7	36
β-strand	1020-1023	4	36
β-strand	1026	1	37
β-strand	1036-1038	3	38
β-strand	1043-1047	5	38
β-strand	1052-1057	6	38
β-strand	1088	1	37
β-strand	1090-1096	7	38
β-strand	1104	1	12
β-strand	1117-1119	3	12
β-strand	1126-1131	6	12
α-helix	1135-1151	17
α-helix	1160-1164	5
β-strand	1171	1	38
β-strand	1173-1174	2	12
α-helix	1176-1179	4
α-helix	1181-1184	4
α-helix	1187-1197	11
α-helix	1201-1215	15

Chain F: 3 helices, 3 β-strands

Element	Residues	Length	Sheet
α-helix	20-41	22
β-strand	46-48	3	7
β-strand	54-56	3	7
β-strand	61-63	3	7
α-helix	66-70	5
α-helix	79-89	11

Chain L: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	13-25	13
α-helix	31-35	5
α-helix	43-52	10

Chain T: 11 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	459-461	3
α-helix	462-468	7
α-helix	472-474	3
α-helix	477-479	3
α-helix	485-492	8
α-helix	502-504	3
α-helix	526-529	4
α-helix	533-544	12
α-helix	569-576	8
α-helix	611-617	7
α-helix	632-639	8
β-strand	651	1	10
β-strand	655	1	10
β-strand	683	1	11
β-strand	686	1	11

6 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Cell division cycle 5-like protein	L	protein	802	Homo sapiens	Q99459 (AlphaFold model)
PHD finger-like domain-containing protein 5A	y	protein	110	Homo sapiens	Q7RTV0 (AlphaFold model)
MINX M3 pre-mRNA	Z	RNA	230	synthetic construct
Splicing factor 3A subunit 2	F	protein	464	Homo sapiens	Q15428 (AlphaFold model)
Splicing factor 3A subunit 3	4	protein	501	Homo sapiens	Q12874 (AlphaFold model)
Splicing factor 3B subunit 1	u	protein	1304	Homo sapiens	O75533
Splicing factor 3B subunit 2	T	protein	895	Homo sapiens	Q13435
Splicing factor 3B subunit 3	E	protein	1217	Homo sapiens	Q15393
Splicing factor 3B subunit 4	w	protein	424	Homo sapiens	Q15427
Splicing factor 3B subunit 5	x	protein	86	Homo sapiens	Q9BWJ5
Splicing factor 3B subunit 6	z	protein	125	Homo sapiens	Q9Y3B4
Smad nuclear-interacting protein 1	0	protein	396	Homo sapiens	Q8TAD8

4 more molecules are not listed.

Sequence of entity 1 (L), FASTA

>7ABH_1 Cell division cycle 5-like protein (chains L)
MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKK
TEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDP
RKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEAR
RLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR
KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAP
QISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQD
RILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGA
EGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGL
LGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKA
VQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKG
KTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQV
WEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKIL
LGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQER
EKELQHRYADLLLEKETLKSKF

Sequence of entity 2 (y), FASTA

>7ABH_2 PHD finger-like domain-containing protein 5A (chains y)
MAKHHPDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVI
CGGPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDLFYERKKYGFKKR

Sequence of entity 3 (Z), FASTA

>7ABH_3 MINX M3 pre-mRNA (chains Z)
GGGAGACGGAAUUCGAGCUCGCCCACUCUUGGAUCGGAAACCCGUCGGCCUCCGAACGGU
AAGAGCCUAGCAUGUAGAACUGGUUACCUGCAGCCCAAGCUUGCUGCACGUCUAGGGCGC
AGUAGUCCAGGGUUUCCUUGAUGAUGUCAUACUUAUCCUGUCCCUUUUUUUUCCACAGCU
CGCGGUUGAGGACAAACUCUUCGCGGUCUUUCCAGUGGGGAUCCAAUAUC

Sequence of entity 4 (F), FASTA

>7ABH_4 Splicing factor 3A subunit 2 (chains F)
MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCL
TLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAPAQPAPEKVKVEVKKFVKIGRPGYKVT
KQRDSEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIA
FKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNG
LPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASG
VHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP
APGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPG
VHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN

Sequence of entity 5 (4), FASTA

>7ABH_5 Splicing factor 3A subunit 3 (chains 4)
METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDL
YDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENP
SEEAQNLVEFTDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQLFDIPKERKNA
EYKRYLEMLLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENGTFPGWPKETSSALTHA
GAHLDLSAFSSWEELASLGLDRLKSALLALGLKCGGTLEERAQRLFSTKGKSLESLDTSL
FAKNPKSKGTKRDTERNKDIAFLEAQIYEYVEILGEQRHLTHENVQRKQARTGEEREEEE
EEQISESESEDEENEIIYNPKNLPLGWDGKPIPYWLYKLHGLNINYNCEICGNYTYRGPK
AFQRHFAEWRHAHGMRCLGIPNTAHFANVTQIEDAVSLWAKLKLQKASERWQPDTEEEYE
DSSGNVVNKKTYEDLKRQGLL

Sequence of entity 6 (u), FASTA

>7ABH_6 Splicing factor 3B subunit 1 (chains u)
MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
KHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGE
LKVVNGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAK
GSETPGATPGSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTE
RDTPGHGSGWAETPRTDRGGDSIGETPTPGASKRKSRWDETPASQMGGSTPVLTPGKTPI
GTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAG
YVPIRTPARKLTATPTPLGGMTGFHMQTEDRTMKSVNDQPSGNLPFLKPDDIQYFDKLLV
DVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLM
SPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNL
AKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQA
RHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYG
IESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP
DEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVEL
ANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAF
QEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAV
VMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRL
TPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNT
FGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPE
LNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVY
GFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARK
VRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL

Sequence of entity 7 (T), FASTA

>7ABH_7 Splicing factor 3B subunit 2 (chains T)
MATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGNREELVERLQSYTRQ
TGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFP
MAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQ
QKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMG
APVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDA
RSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRGS
DSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAAPK
KKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDV
TAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREAL
QEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETR
LKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPES
CSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSE
EEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSET
PQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAM
TQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF

Sequence of entity 8 (E), FASTA

>7ABH_8 Splicing factor 3B subunit 3 (chains E)
MFLYNLTLQRATGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFG
VIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQF
LAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENP
MFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPG
GSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFF
FLAQTEQGDIFKITLETDEDMVTEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQ
IAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDT
PQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHIEDEFDAYIIVSFVN
ATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVNEWKTPG
KKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQ
RSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGTEKQDELGERGSI
GFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSW
LSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFP
LQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAA
AFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTG
EDWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVL
IGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQ
LIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRG
LLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDF
FQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRT
PPEVSKKLEDIRTRYAF

Sequence of entity 9 (w), FASTA

>7ABH_9 Splicing factor 3B subunit 4 (chains w)
MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVE
FLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTF
SAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK
DSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPP
GSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGG
MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGS
PMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG
PLPQ

Sequence of entity 10 (x), FASTA

>7ABH_10 Splicing factor 3B subunit 5 (chains x)
MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENES
KARVRFNLMEKMLQPCGPPADKPEEN

Sequence of entity 11 (z), FASTA

>7ABH_11 Splicing factor 3B subunit 6 (chains z)
MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTA
YVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGIN
TDPPK

Sequence of entity 12 (0), FASTA

>7ABH_12 Smad nuclear-interacting protein 1 (chains 0)
MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEP
ARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGRE
DRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEERE
FYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFR
GVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCS
KQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKF
GFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS

Primary citation

Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Townsend, C., Leelaram, M.N., Agafonov, D.E. et al. Science (2020) 370. DOI 10.1126/science.abc3753 · PubMed

Other PDB entries of the same protein (UniProt Q99459 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9S2E 2.4 Å, Human intron-lariat spliceosome-Aquarius (ILSaqr)
8C6J 2.8 Å, Human spliceosomal PM5 C* complex
6ID1 2.86 Å, Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex)…
7DVQ 2.89 Å, Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)
6ID0 2.9 Å, Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1…
9XTT 2.92 Å, Human minor spliceosome branching-completed C complex (after step-I)
6ICZ 3.0 Å, Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom
8I0R 3.0 Å, The cryo-EM structure of human Bact-I complex
8I0T 3.0 Å, The cryo-EM structure of human Bact-III complex
8I0V 3.0 Å, The cryo-EM structure of human post-Bact complex
9XU3 3.0 Å, Human minor spliceosome exon-ligation-ready C* complex (prior to step-II)
7QTT 3.1 Å, Structural organization of a late activated human spliceosome (Baqr, core region)

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