Crystal Structure of H3(1-13)/PHF14-PZP fusion protein. Determined by X-ray diffraction at 2.0 Å resolution. Released 28 Jul 2021.
Explore 7D8A in 3D Show helices and sheets RCSB PDB PDBe
7D8A contains 10 α-helices and 15 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 302-304 | 3 | 1 |
| β-strand | 311-313 | 3 | 1 |
| α-helix | 314-316 | 3 | |
| α-helix | 322-325 | 4 | |
| β-strand | 335-336 | 2 | 2 |
| α-helix | 341-344 | 4 | |
| β-strand | 351 | 1 | 3 |
| β-strand | 354 | 1 | 3 |
| β-strand | 361-363 | 3 | 4 |
| β-strand | 364 | 1 | 5 |
| β-strand | 369-371 | 3 | 4 |
| α-helix | 372-377 | 6 | |
| β-strand | 383 | 1 | 5 |
| β-strand | 392 | 1 | 5 |
| α-helix | 396-400 | 5 | |
| α-helix | 413-415 | 3 | |
| β-strand | 421-423 | 3 | 6 |
| β-strand | 432-434 | 3 | 6 |
| α-helix | 435-440 | 6 | |
| β-strand | 444-446 | 3 | 7 |
| α-helix | 449-451 | 3 | |
| β-strand | 457-459 | 3 | 7 |
| α-helix | 467-484 | 18 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 2-3 | 2 | 2 |
| α-helix | 5-7 | 3 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| PHD finger protein 14 | A | protein | 210 | Danio rerio | A0A286Y9D1 (AlphaFold model) |
| Gene for histone H3 (germline gene) | E | protein | 18 | Homo sapiens | V9H1G0 (AlphaFold model) |
>7D8A_1 PHD finger protein 14 (chains A) SSQRMEHILICCVCLGDNSEDADEIIQCDNCGVTVHEGCYGVDGESDSIMSSASENSTEP WFCDACKNGVSPSCELCPSQDGIFKETDAGRWVHVVCALYVPGVAFGDIDKLRPVTLTEM NYSKYGAKECSLCEDTRFARTGVCISCDAGMCRSFFHVTCAQREGLLSEAAAEEDIADPF FAYCKQHADRFDRKWKRKNYLALQSYCKVS
>7D8A_2 Gene for histone H3 (germline gene) (chains E) ARTKQTARKSTGGSGSGS
Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14. Zheng, S., Bi, Y., Chen, H. et al. Nucleic Acids Res (2021) 49:8961-8973. DOI 10.1093/nar/gkab670 · PubMed
Other PDB entries of the same protein (UniProt A0A286Y9D1 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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