7DU2: DNA-directed RNA polymerase III subunit RPC1

RNA polymerase III EC complex in post-translocation state. Determined by electron microscopy at 3.35 Å resolution. Released 17 Mar 2021.

Method: Electron microscopy
Resolution: 3.35 Å
Organism: Homo sapiens
Chains: 20
Atoms: 36,616
Mol. weight: 720.14 kDa
Ligands: MG, ZN, SF4
Released: 17 Mar 2021

Explore 7DU2 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7DU2 contains 183 α-helices and 237 β-strands across 17 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 60 helices, 52 β-strands

Element	Residues	Length	Sheet
α-helix	5	1
β-strand	6	1	1
α-helix	7	1
β-strand	14-21	8	2
α-helix	29-31	3
β-strand	34-35	2	3
β-strand	84-93	10	3
α-helix	98-105	8
β-strand	108	1	4
β-strand	115	1	4
α-helix	119-129	11
α-helix	137-150	14
β-strand	155	1	5
β-strand	162	1	5
β-strand	166	1	6
β-strand	175-176	2	6
β-strand	216-217	2	6
α-helix	220-226	7
α-helix	236-238	3
α-helix	247-250	4
β-strand	251-257	7	3
α-helix	258-259	2
α-helix	260-262	3
α-helix	280-295	16
α-helix	303-319	17
α-helix	352-356	5
β-strand	360-361	2	7
β-strand	364-371	8	8
β-strand	379-382	4	8
α-helix	384-387	4
β-strand	391-395	5	9
α-helix	401-408	8
β-strand	418-422	5	9
α-helix	427-429	3
α-helix	437-442	6
β-strand	449-453	5	9
β-strand	458-463	6	8
α-helix	470-472	3
β-strand	475-480	6	8
β-strand	486-488	3	8
β-strand	504-508	5	8
α-helix	513-517	5
α-helix	518-522	5
β-strand	530	1	10
β-strand	537	1	10
α-helix	544-552	9
α-helix	561-568	8
α-helix	583-586	4
β-strand	588	1	11
β-strand	594	1	11
α-helix	597-605	9
β-strand	617-620	4	12
β-strand	637-640	4	12
β-strand	645-647	3	12
α-helix	663-671	9
α-helix	674-694	21
α-helix	700-702	3
α-helix	707-732	26
α-helix	747-770	24
α-helix	776-782	7
α-helix	789-792	4
α-helix	793-797	5
β-strand	801	1	13
α-helix	809-810	2
β-strand	813	1	14
β-strand	816	1	14
β-strand	833	1	13
α-helix	844-876	33
β-strand	883-884	2	15
β-strand	890-891	2	15
β-strand	897-899	3	15
α-helix	902-904	3
α-helix	912	1
β-strand	913	1	16
β-strand	917	1	16
α-helix	921-931	11
α-helix	945-951	7
α-helix	965-986	22
α-helix	998-1002	5
α-helix	1010-1024	15
α-helix	1027-1028	2
α-helix	1033-1046	14
α-helix	1067-1075	9
β-strand	1085-1089	5	17
α-helix	1095-1105	11
β-strand	1108-1109	2	18
α-helix	1111-1113	3
β-strand	1118-1122	5	19
β-strand	1125-1129	5	19
β-strand	1130	1	20
α-helix	1134-1139	6
α-helix	1146-1153	8
β-strand	1166-1168	3	20
β-strand	1173-1175	3	20
α-helix	1187-1195	9
α-helix	1196-1198	3
β-strand	1200-1202	3	18
β-strand	1210-1213	4	17
β-strand	1224-1227	4	17
α-helix	1232-1236	5
β-strand	1241-1247	7	17
α-helix	1251-1258	8
α-helix	1261-1277	17
α-helix	1284-1294	11
β-strand	1297-1298	2	21
α-helix	1305-1309	5
α-helix	1315-1319	5
α-helix	1324-1333	10
β-strand	1337-1339	3	2
α-helix	1346-1349	4
α-helix	1351-1353	3
β-strand	1361-1364	4	1

Chain B: 40 helices, 80 β-strands

Element	Residues	Length	Sheet
α-helix	29-37	9
α-helix	42-52	11
β-strand	65	1	22
β-strand	75	1	22
β-strand	82	1	23
β-strand	86-87	2	24
β-strand	95-96	2	24
α-helix	99-102	4
β-strand	110-113	4	23
β-strand	134-137	4	23
α-helix	152-157	6
β-strand	169-171	3	25
β-strand	174-178	5	25
β-strand	180-184	5	26
β-strand	189-191	3	27
β-strand	199-201	3	27
β-strand	204	1	28
β-strand	211	1	28
β-strand	214-216	3	27
β-strand	218-219	2	29
β-strand	222-223	2	29
β-strand	224	1	30
β-strand	230	1	31
β-strand	235	1	30
α-helix	236-242	7
α-helix	248-255	8
α-helix	262-265	4
α-helix	266-270	5
α-helix	271-274	4
α-helix	281-291	11
β-strand	292	1	31
α-helix	311-314	4
α-helix	329-343	15
β-strand	360-363	4	26
α-helix	365-391	27
α-helix	405-407	3
α-helix	408-420	13
β-strand	423	1	32
β-strand	426	1	33
β-strand	431	1	33
β-strand	434	1	32
β-strand	437-439	3	25
α-helix	446-452	7
β-strand	455-456	2	26
α-helix	471-472	2
α-helix	473-475	3
β-strand	479	1	34
β-strand	493-494	2	26
β-strand	496	1	34
β-strand	501-502	2	35
α-helix	509-518	10
β-strand	538-541	4	36
β-strand	544-548	5	36
α-helix	552-565	14
β-strand	573-577	5	36
β-strand	582-586	5	36
β-strand	591	1	26
β-strand	592-598	7	35
β-strand	599	1	37
β-strand	604	1	37
α-helix	609-616	8
α-helix	621-626	6
β-strand	630-634	5	35
α-helix	637-640	4
β-strand	644	1	35
β-strand	656-657	2	35
α-helix	661-664	4
α-helix	680-691	12
β-strand	693	1	38
β-strand	709-712	4	39
β-strand	716	1	40
α-helix	724-728	5
β-strand	739-741	3	41
β-strand	756-758	3	42
α-helix	761-764	4
β-strand	769-772	4	39
β-strand	773	1	43
β-strand	776-778	3	44
β-strand	789	1	45
α-helix	815-816	2
β-strand	820-821	2	43
β-strand	825-833	9	45
β-strand	851-858	8	45
β-strand	864-866	3	43
β-strand	870-872	3	44
β-strand	880-882	3	44
β-strand	885-886	2	43
β-strand	896-897	2	46
β-strand	905-906	2	46
β-strand	909-911	3	42
α-helix	913-915	3
β-strand	919	1	47
β-strand	927-928	2	42
α-helix	929-930	2
α-helix	933-937	5
α-helix	940-955	16
α-helix	969-976	8
β-strand	986-987	2	48
β-strand	989	1	47
β-strand	990	1	49
β-strand	997	1	49
α-helix	998	1
β-strand	1002-1003	2	48
β-strand	1005-1007	3	41
α-helix	1009-1010	2
β-strand	1011	1	46
β-strand	1012	1	38
α-helix	1016-1018	3
β-strand	1021-1023	3	8
β-strand	1028	1	50
β-strand	1035	1	50
β-strand	1045-1046	2	7
α-helix	1049-1057	9
α-helix	1061-1065	5
α-helix	1066-1070	5
β-strand	1075-1080	6	51
β-strand	1086	1	51
β-strand	1101-1106	6	51
α-helix	1108-1117	10
β-strand	1123-1129	7	2

Chain C: 10 helices, 19 β-strands

Element	Residues	Length	Sheet
β-strand	13-15	3	52
α-helix	42-47	6
β-strand	50	1	53
β-strand	53-54	2	54
β-strand	61	1	55
β-strand	62-63	2	54
β-strand	66	1	53
α-helix	73-82	10
β-strand	86-97	12	56
α-helix	103-109	7
β-strand	140-145	6	56
β-strand	167-169	3	57
β-strand	173-175	3	56
β-strand	198-201	4	57
β-strand	207-217	11	56
α-helix	223-225	3
β-strand	228-230	3	58
β-strand	233-241	9	52
α-helix	249-256	8
α-helix	259-261	3
β-strand	263	1	59
β-strand	274	1	59
α-helix	278-280	3
α-helix	287-289	3
α-helix	293-295	3
β-strand	297-308	12	52
β-strand	310	1	55
β-strand	311-312	2	58
α-helix	318-342	25

Chain D: 8 helices, 1 β-strand

Element	Residues	Length	Sheet
β-strand	3-5	3	1
α-helix	13-27	15
α-helix	34-37	4
α-helix	41-55	15
α-helix	63-76	14
α-helix	80-89	10
α-helix	94-95	2
α-helix	96-100	5
α-helix	112-121	10

Chain E: 9 helices, 12 β-strands

Element	Residues	Length	Sheet
α-helix	12-23	12
β-strand	26	1	66
α-helix	30-33	4
α-helix	37-40	4
β-strand	61-62	2	67
β-strand	64	1	66
β-strand	72-73	2	67
β-strand	81-82	2	68
α-helix	84-89	6
α-helix	92-96	5
β-strand	103-105	3	69
β-strand	109-110	2	68
α-helix	114-120	7
β-strand	128-130	3	69
α-helix	132-135	4
β-strand	147-150	4	21
α-helix	153-163	11
β-strand	172-173	2	21
α-helix	178-183	6
β-strand	190-195	6	21
β-strand	203-209	7	21

Chain F: 3 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	56	1	70
α-helix	59-73	15
α-helix	77-79	3
α-helix	89-98	10
β-strand	104-109	6	1
β-strand	115-119	5	1
β-strand	124	1	70

Chain G: 2 helices, 15 β-strands

Element	Residues	Length	Sheet
β-strand	3-13	11	1
α-helix	15-17	3
α-helix	22-31	10
β-strand	37-39	3	1
β-strand	43-45	3	1
β-strand	50-54	5	1
β-strand	58-59	2	1
β-strand	66-77	12	1
β-strand	83-87	5	60
β-strand	88	1	61
β-strand	92-93	2	62
β-strand	96-97	2	62
β-strand	100	1	61
β-strand	101	1	63
β-strand	105	1	63
β-strand	146-152	7	60
β-strand	189-191	3	60

Chain H: 0 helices, 12 β-strands

Element	Residues	Length	Sheet
β-strand	4-14	11	71
β-strand	25-31	7	71
β-strand	39-44	6	71
β-strand	55-61	7	71
β-strand	90	1	72
β-strand	92	1	11
β-strand	93-98	6	71
β-strand	113-118	6	71
β-strand	121-126	6	71
β-strand	139-143	5	71
β-strand	145	1	72
β-strand	146-147	2	71

9 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase III subunit RPC1	A	protein	1390	Homo sapiens	O14802 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC2	B	protein	1133	Homo sapiens	Q9NW08 (AlphaFold model)
DNA-directed RNA polymerases I and III subunit RPAC1	C	protein	346	Homo sapiens	O15160 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC8	G	protein	204	Homo sapiens	Q9Y535 (AlphaFold model)
DNA-directed RNA polymerases I and III subunit RPAC2	K	protein	133	Homo sapiens	P0DPB6
DNA-directed RNA polymerases I, II, and III subunit RPABC4	L	protein	58	Homo sapiens	P53803
DNA-directed RNA polymerase III subunit RPC6	P	protein	316	Homo sapiens	Q9H1D9
DNA-directed RNA polymerases I, II, and III subunit RPABC1	E	protein	210	Homo sapiens	P19388
DNA-directed RNA polymerases I, II, and III subunit RPABC2	F	protein	127	Homo sapiens	P61218
DNA-directed RNA polymerases I, II, and III subunit RPABC3	H	protein	150	Homo sapiens	P52434
DNA-directed RNA polymerases I, II, and III subunit RPABC5	J	protein	67	Homo sapiens	P62875
DNA-directed RNA polymerase III subunit RPC3	O	protein	534	Homo sapiens	Q9BUI4

8 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>7DU2_1 DNA-directed RNA polymerase III subunit RPC1 (chains A)
MVKEQFRETDVAKKISHICFGMKSPEEMRQQAHIQVVSKNLYSQDNQHAPLLYGVLDHRM
GTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVIGILQMICKTCCHIMLSQE
EKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCGAFNGTVKKCGLLKIIHEKYK
TNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENLNPLVVLNLFKRIPAEDVPLLLM
NPEAGKPSDLILTRLLVPPLCIRPSVVSDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISG
AKTQMIMEDWDFLQLQCALYINSELSGIPLNMAPKKWTRGFVQRLKGKQGRFRGNLSGKR
VDFSGRTVISPDPNLRIDEVAVPVHVAKILTFPEKVNKANINFLRKLVQNGPEVHPGANF
IQQRHTQMKRFLKYGNREKMAQELKYGDIVERHLIDGDVVLFNRQPSLHKLSIMAHLARV
KPHRTFRFNECVCTPYNADFDGDEMNLHLPQTEEAKAEALVLMGTKANLVTPRNGEPLIA
AIQDFLTGAYLLTLKDTFFDRAKACQIIASILVGKDEKIKVRLPPPTILKPVTLWTGKQI
FSVILRPSDDNPVRANLRTKGKQYCGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSK
NNIFYILLRDWGQNEAADAMSRLARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAG
YKKCDEYIEALNTGKLQQQPGCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTM
ALCGSKGSFINISQMIACVGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYS
GLTPTEFFFHTMAGREGLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQF
IYGGDGLDPAAMEGKDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLC
CQDSFLQEIKKFIKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRD
KYMRAQMEPGSAVGALCAQSIGEPGTQMTLKTFHFAGVASMNITLGVPRIKEIINASKAI
STPIITAQLDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLL
RLEVNAETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVV
VQGIPEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGI
EAARTTIINEIQYTMVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLAS
FEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPLIFD
TNEFHIPLVT

Sequence of entity 2 (B), FASTA

>7DU2_2 DNA-directed RNA polymerase III subunit RPC2 (chains B)
MDVLAEEFGNLTPEQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMK
ANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT
RGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILI
QEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIF
KAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGG
PKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNK
RLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAIS
TGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLC
PSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVF
LNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVK
KQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIE
PFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMV
KTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLK
RYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPL
EGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSR
HGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHY
GTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKM
HARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVC
GQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE

Sequence of entity 3 (C), FASTA

>7DU2_3 DNA-directed RNA polymerases I and III subunit RPAC1 (chains C)
MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENS
LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPR
LFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGN
QADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT
LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLA
RVRDHYIFSVESTGVLPPDVLVSEAIKVLMGKCRRFLDELDAVQMD

Sequence of entity 4 (G), FASTA

>7DU2_4 DNA-directed RNA polymerase III subunit RPC8 (chains G)
MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVF
PGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKF
DEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKK
EAPYTLVGSISEPGLGLLSWWTSN

Sequence of entity 5 (K), FASTA

>7DU2_5 DNA-directed RNA polymerases I and III subunit RPAC2 (chains K)
MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM
KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD
YKDQKASRNESTF

Sequence of entity 6 (L), FASTA

>7DU2_6 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (chains L)
MDTQKDVQPPKQQPMIYICGECHTENEIKSRDPIRCRECGYRIMYKKRTKRLVVFDAR

Sequence of entity 7 (P), FASTA

>7DU2_7 DNA-directed RNA polymerase III subunit RPC6 (chains P)
MAEVKVKVQPPDADPVEIENRIIELCHQFPHGITDQVIQNEMPHIEAQQRAVAINRLLSM
GQLDLLRSNTGLLYRIKDSQNAGKMKGSDNQEKLVYQIIEDAGNKGIWSRDIRYKSNLPL
TEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFESEFVEVL
NQQCFKFLQSKAETARESKQNPMIQRNSSFASSHEVWKYICELGISKVELSMEDIETILN
TLIYDGKVEMTIIAAKEGTVGSVDGHMKLYRAVNPIIPPTGLVRAPCGLCPVFDDCHEGG
EISPSNCIYMTEWLEF

Sequence of entity 8 (E), FASTA

>7DU2_8 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (chains E)
MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSEGRPRRTDLTV
LVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVD
MAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVA
RYFGIKRGQVVKIIRPSETAGRYITYRLVQ

Sequence of entity 9 (F), FASTA

>7DU2_9 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (chains F)
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKY
ERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGV
DELIITD

Sequence of entity 10 (H), FASTA

>7DU2_10 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (chains H)
MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESESFKMDLILDVNIQIYPVDLGDKFRLVI
ASTLYEDGTLDDGEYNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLSAYVSYGG
LLMRLQGDANNLHGFEVDSRVYLLMKKLAF

Sequence of entity 11 (J), FASTA

>7DU2_11 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (chains J)
MIIPVRCFTCGKIVGNKWEAYLGLLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLL
NYAPLEK

Sequence of entity 12 (O), FASTA

>7DU2_12 DNA-directed RNA polymerase III subunit RPC3 (chains O)
MTQAEIKLCSLLLQEHFGEIVEKIGVHLIRTGSQPLRVIAHDTGTSLDQVKKALCVLVQH
NLVSYQVHKRGVVEYEAQCSRVLRMLRYPRYIYTTKTLYSDTGELIVEELLLNGKLTMSA
VVKKVADRLTETMEDGKTMDYAEVSNTFVRLADTHFVQRCPSVPTTENSDPGPPPPAPTL
VINEKDMYLVPKLSLIGKGKRRRSSDEDAAGEPKAKRPKYTTDNKEPIPDDGIYWQANLD
RFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMSEITTSSSAPFTQPLSSNEIFRSLPVG
YNISKQVLDQYLTLLADDPLEFVGKSGDSGGGMYVINLHKALASLATATLESVVQERFGS
RCARIFRLVLQKKHIEQKQVEDFAMIPAKEAKDMLYKMLSENFMSLQEIPKTPDHAPSRT
FYLYTVNILSAARMLLHRCYKSIANLIERRQFETKENKRLLEKSQRVEAIIASMQATGAE
EAQLQEIEEMITAPERQQLETLKRNVNKLDASEIQVDETIFLLESYIECTMKRQ

Ligands and cofactors

ID	Name	Formula	Copies
MG	Magnesium ion	Mg	1
ZN	Zinc ion	Zn	6
SF4	Iron/sulfur cluster	Fe4 S4	1

Primary citation

Structure of human RNA polymerase III elongation complex. Li, L., Yu, Z., Zhao, D. et al. Cell Res (2021) 31:791-800. DOI 10.1038/s41422-021-00472-2 · PubMed

Other PDB entries of the same protein (UniProt O14802 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7AE1 2.8 Å, Cryo-EM structure of human RNA Polymerase III elongation complex 1
9K39 2.8 Å, Human RNA Polymerase III de novo transcribing complex 8 (TC8)
7D58 2.9 Å, cryo-EM structure of human RNA polymerase III in elongating state
9K36 2.9 Å, Human RNA Polymerase III de novo transcribing complex 12 (TC12)
9K2G 3.0 Å, Human RNA Polymerase III de novo transcribing complex 13 (TC13)
9K3U 3.0 Å, Human RNA Polymerase III de novo transcribing complex 5 (TC5)
7AE3 3.1 Å, Cryo-EM structure of human RNA Polymerase III elongation complex 3
7D59 3.1 Å, cryo-EM structure of human RNA polymerase III in apo state
9K38 3.1 Å, Human RNA Polymerase III de novo transcribing complex 6 (TC6)
9FSO 3.28 Å, Human RNA Polymerase III Class III Open Pre-initiation Complex 1 (OC1)
7A6H 3.3 Å, Cryo-EM structure of human apo RNA Polymerase III
9LXN 3.3 Å, Human RNA Polymerase III de novo transcribing complex 5 (TC5)(without 3'dATP)

Browse structure collections

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