7NVM: T-complex protein 1 subunit alpha

Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound. Determined by electron microscopy at 3.1 Å resolution. Released 2 Mar 2022.

Method: Electron microscopy
Resolution: 3.1 Å
Organisms: Homo sapiens, Lama glama
Chains: 20
Atoms: 71,008
Mol. weight: 1054.06 kDa
Ligands: AF3, MG, ADP
Released: 2 Mar 2022

Explore 7NVM in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7NVM contains 394 α-helices and 441 β-strands across 20 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain a: 22 helices, 27 β-strands

Element	Residues	Length	Sheet
β-strand	9-13	5	65
α-helix	15-33	19
β-strand	42-46	5	66
β-strand	52-55	4	66
α-helix	58-64	7
β-strand	67	1	67
α-helix	70-85	16
α-helix	90-109	20
α-helix	114-135	22
β-strand	138-139	2	68
α-helix	146-156	11
α-helix	165-178	14
β-strand	181-182	2	69
α-helix	184-186	3
β-strand	188-189	2	69
β-strand	196-199	4	70
α-helix	205-207	3
β-strand	209-212	4	70
β-strand	213-216	4	71
β-strand	228-229	2	71
β-strand	232-237	6	71
β-strand	241	1	72
β-strand	250-252	3	73
β-strand	254	1	74
α-helix	257-281	25
β-strand	285-288	4	71
β-strand	292	1	72
α-helix	294-303	10
β-strand	306-308	3	71
α-helix	313-323	11
β-strand	328	1	71
α-helix	342-344	3
β-strand	346-355	10	71
β-strand	360-367	8	71
β-strand	373-377	5	70
α-helix	382-404	23
β-strand	407-410	4	68
α-helix	414-426	13
α-helix	427-429	3
α-helix	433-445	13
α-helix	447-455	9
α-helix	460-476	17
α-helix	478-485	8
β-strand	486-489	4	75
β-strand	494-497	4	75
α-helix	498-501	4
β-strand	504-506	3	68
α-helix	507-525	19
β-strand	527-533	7	65

Chain A: 25 helices, 27 β-strands

Element	Residues	Length	Sheet
β-strand	9-13	5	1
α-helix	15-32	18
α-helix	33-35	3
β-strand	42-46	5	2
β-strand	52-55	4	2
α-helix	58-64	7
β-strand	67	1	3
α-helix	70-85	16
α-helix	90-109	20
α-helix	114-135	22
β-strand	138-139	2	4
α-helix	140-142	3
α-helix	146-156	11
α-helix	165-179	15
β-strand	181-182	2	5
α-helix	184-186	3
β-strand	188-189	2	5
β-strand	196-199	4	6
α-helix	205-207	3
β-strand	209-212	4	6
β-strand	213-216	4	7
β-strand	228-229	2	7
β-strand	232-237	6	7
β-strand	241	1	8
β-strand	250-252	3	9
β-strand	254	1	10
α-helix	257-281	25
β-strand	285-288	4	7
β-strand	292	1	8
α-helix	294-303	10
β-strand	306-308	3	7
α-helix	313-323	11
β-strand	328	1	7
α-helix	342-344	3
β-strand	346-355	10	7
β-strand	360-367	8	7
β-strand	373-377	5	6
α-helix	382-404	23
β-strand	407-410	4	4
α-helix	414-426	13
α-helix	427-429	3
α-helix	433-445	13
α-helix	447-455	9
α-helix	460-476	17
α-helix	478-485	8
β-strand	486-489	4	11
β-strand	494-497	4	11
α-helix	498-501	4
β-strand	504-506	3	4
α-helix	507-525	19
β-strand	527-533	7	1
α-helix	534-535	2

Chain b: 21 helices, 21 β-strands

Element	Residues	Length	Sheet
β-strand	17-19	3	76
α-helix	21-39	19
β-strand	49-53	5	77
β-strand	61-64	4	77
α-helix	67-72	6
α-helix	79-94	16
α-helix	99-118	20
α-helix	123-144	22
β-strand	146-147	2	78
α-helix	152-168	17
α-helix	171-175	5
α-helix	176-188	13
α-helix	196-198	3
β-strand	199-206	8	79
α-helix	209-211	3
β-strand	213-214	2	79
β-strand	218-220	3	80
β-strand	224	1	80
β-strand	232-240	9	80
β-strand	254-258	5	73
α-helix	261-283	23
β-strand	289-292	4	80
α-helix	298-307	10
β-strand	310-312	3	80
α-helix	317-327	11
β-strand	332	1	80
α-helix	338-340	3
α-helix	341-343	3
β-strand	344-354	11	80
β-strand	357-365	9	80
β-strand	371-377	7	79
α-helix	380-402	23
β-strand	405-408	4	78
α-helix	412-427	16
α-helix	431-452	22
α-helix	458-471	14
β-strand	476-479	4	81
β-strand	484-487	4	81
α-helix	488-491	4
β-strand	494-496	3	78
α-helix	497-515	19
β-strand	517-522	6	76

Chain B: 20 helices, 20 β-strands

Element	Residues	Length	Sheet
β-strand	17-19	3	12
α-helix	21-39	19
β-strand	49-52	4	13
β-strand	63-64	2	13
α-helix	67-72	6
α-helix	79-94	16
α-helix	99-118	20
α-helix	125-144	20
β-strand	146-147	2	14
α-helix	152-168	17
α-helix	171-175	5
α-helix	176-188	13
β-strand	199-206	8	15
α-helix	209-211	3
β-strand	213-214	2	15
β-strand	218-220	3	16
β-strand	232-240	9	16
β-strand	254-258	5	9
α-helix	261-283	23
β-strand	289-292	4	16
α-helix	298-307	10
β-strand	310-312	3	16
α-helix	317-327	11
β-strand	332	1	16
α-helix	338-340	3
α-helix	342-343	2
β-strand	344-354	11	16
β-strand	357-365	9	16
β-strand	371-377	7	15
α-helix	380-402	23
β-strand	405-408	4	14
α-helix	412-426	15
α-helix	431-452	22
α-helix	458-471	14
β-strand	476-479	4	17
β-strand	484-487	4	17
α-helix	488-491	4
β-strand	494-496	3	14
α-helix	497-515	19
β-strand	517-522	6	12

Chain d: 23 helices, 23 β-strands

Element	Residues	Length	Sheet
α-helix	29-47	19
β-strand	58-62	5	65
β-strand	68-71	4	65
α-helix	74-80	7
α-helix	86-101	16
α-helix	106-126	21
α-helix	132-151	20
β-strand	153-154	2	82
α-helix	160-172	13
α-helix	175-177	3
α-helix	180-193	14
α-helix	205-207	3
β-strand	208-212	5	83
β-strand	215	1	84
α-helix	218-220	3
β-strand	222	1	83
β-strand	227-229	3	85
α-helix	232-233	2
β-strand	241-249	9	85
β-strand	253	1	86
β-strand	262-266	5	73
α-helix	269-291	23
β-strand	297-301	5	85
β-strand	309	1	86
α-helix	311-319	9
β-strand	323-328	6	85
α-helix	333-340	8
β-strand	345	1	85
α-helix	348-350	3
α-helix	353-355	3
β-strand	357-366	10	85
β-strand	372-377	6	85
β-strand	386-390	5	83
β-strand	392	1	84
α-helix	395-416	22
β-strand	420-423	4	82
α-helix	427-441	15
α-helix	446-458	13
α-helix	460-466	7
α-helix	473-486	14
β-strand	491-494	4	87
β-strand	499-502	4	87
α-helix	503-505	3
β-strand	509-511	3	82
α-helix	512-530	19
β-strand	532-537	6	77

Chain D: 23 helices, 23 β-strands

Element	Residues	Length	Sheet
α-helix	29-48	20
α-helix	49-51	3
β-strand	58-62	5	1
β-strand	68-71	4	1
α-helix	74-80	7
α-helix	86-101	16
α-helix	106-126	21
α-helix	130-151	22
β-strand	153-154	2	18
α-helix	160-172	13
α-helix	180-193	14
α-helix	205-207	3
β-strand	208-212	5	19
β-strand	215	1	20
α-helix	218-220	3
β-strand	222-224	3	19
β-strand	227-229	3	21
α-helix	232-233	2
β-strand	240-249	10	21
β-strand	253	1	22
β-strand	262-266	5	9
α-helix	269-291	23
β-strand	297-301	5	21
β-strand	309	1	22
α-helix	311-319	9
β-strand	323-328	6	21
α-helix	333-340	8
β-strand	344-345	2	21
α-helix	348-350	3
α-helix	353-355	3
β-strand	357-366	10	21
β-strand	372-377	6	21
β-strand	386-390	5	19
β-strand	392	1	20
α-helix	395-417	23
β-strand	420-423	4	18
α-helix	427-442	16
α-helix	447-458	12
α-helix	460-469	10
α-helix	473-486	14
β-strand	491-494	4	23
β-strand	499-502	4	23
α-helix	503-505	3
β-strand	509-511	3	18
α-helix	512-530	19
β-strand	532-536	5	13

Chain e: 23 helices, 21 β-strands

Element	Residues	Length	Sheet
β-strand	19	1	88
β-strand	28-29	2	89
α-helix	31-48	18
α-helix	49-51	3
α-helix	56-57	2
β-strand	58-62	5	76
β-strand	68-71	4	76
α-helix	74-80	7
α-helix	86-101	16
α-helix	108-125	18
α-helix	130-151	22
β-strand	153-154	2	90
α-helix	163-173	11
α-helix	177-181	5
α-helix	182-195	14
α-helix	206-208	3
β-strand	209-216	8	91
α-helix	219-221	3
β-strand	223-225	3	91
β-strand	228-230	3	92
β-strand	242-251	10	92
β-strand	263-268	6	73
α-helix	271-294	24
β-strand	299-302	4	92
α-helix	308-316	9
β-strand	321-322	2	92
α-helix	327-337	11
β-strand	342	1	92
α-helix	345-347	3
β-strand	354-363	10	92
β-strand	370-375	6	92
β-strand	383-389	7	91
α-helix	392-414	23
β-strand	417-420	4	90
α-helix	424-437	14
α-helix	443-455	13
α-helix	457-465	9
α-helix	470-483	14
β-strand	489	1	93
β-strand	500	1	93
α-helix	501-504	4
β-strand	507-509	3	90
α-helix	510-528	19
β-strand	530-534	5	89

Chain E: 24 helices, 24 β-strands

Element	Residues	Length	Sheet
β-strand	19	1	24
β-strand	28-29	2	25
α-helix	31-48	18
α-helix	49-51	3
α-helix	56-57	2
β-strand	58-62	5	12
β-strand	68-71	4	12
α-helix	74-80	7
α-helix	86-101	16
α-helix	108-125	18
α-helix	130-151	22
β-strand	153-154	2	26
α-helix	163-173	11
α-helix	177-181	5
α-helix	182-195	14
α-helix	206-208	3
β-strand	209-216	8	27
α-helix	219-221	3
β-strand	223-225	3	27
β-strand	228-230	3	28
β-strand	234	1	28
β-strand	242-251	10	28
β-strand	255	1	29
β-strand	263-268	6	9
α-helix	271-294	24
β-strand	299-302	4	28
β-strand	306	1	29
α-helix	308-316	9
β-strand	321-322	2	28
α-helix	327-337	11
β-strand	342	1	28
α-helix	345-347	3
β-strand	354-363	10	28
β-strand	370-375	6	28
β-strand	383-389	7	27
α-helix	392-414	23
β-strand	417-420	4	26
α-helix	424-437	14
α-helix	442-444	3
α-helix	445-455	11
α-helix	457-465	9
α-helix	470-483	14
β-strand	489	1	30
β-strand	500	1	30
α-helix	501-504	4
β-strand	507-509	3	26
α-helix	510-528	19
β-strand	530-534	5	25

10 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
T-complex protein 1 subunit alpha	A, a	protein	556	Homo sapiens	P17987 (AlphaFold model)
T-complex protein 1 subunit beta	B, b	protein	535	Homo sapiens	P78371 (AlphaFold model)
T-complex protein 1 subunit delta	D, d	protein	539	Homo sapiens	P50991 (AlphaFold model)
T-complex protein 1 subunit epsilon	E, e	protein	541	Homo sapiens	P48643 (AlphaFold model)
T-complex protein 1 subunit gamma	G, g	protein	545	Homo sapiens	P49368
T-complex protein 1 subunit eta	H, h	protein	543	Homo sapiens	Q99832
Nanobody Nb18	N, n	protein	129	Lama glama
T-complex protein 1 subunit theta	Q, q	protein	548	Homo sapiens	P50990
T-complex protein 1 subunit zeta	Z, z	protein	531	Homo sapiens	P40227
Actin, cytoplasmic 2	K	protein	375	Homo sapiens	P63261
Phosducin-like protein 3	P	protein	239	Homo sapiens	Q9H2J4

Sequence of entity 1 (A, a), FASTA

>7NVM_1 T-complex protein 1 subunit alpha (chains A, a)
MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT
ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG
YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK
YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS
LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF
VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE
LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS
IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER
KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD
KHGSYEDAVHSGALND

Sequence of entity 2 (B, b), FASTA

>7NVM_2 T-complex protein 1 subunit beta (chains B, b)
MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA
NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP
EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI
HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA
VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM
REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC

Sequence of entity 3 (D, d), FASTA

>7NVM_3 T-complex protein 1 subunit delta (chains D, d)
MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM
IQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSC
TKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYS
SLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITR
VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLI
QKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAE
LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRA
LIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTEL
RNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR

Sequence of entity 4 (E, e), FASTA

>7NVM_4 T-complex protein 1 subunit epsilon (chains E, e)
MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKM
MVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA
EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNS
CHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP
KKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA
ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQ
EISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVY
GGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR
QVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE
E

Sequence of entity 5 (G, g), FASTA

>7NVM_5 T-complex protein 1 subunit gamma (chains G, g)
MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
DAGQE

Sequence of entity 6 (H, h), FASTA

>7NVM_6 T-complex protein 1 subunit eta (chains H, h)
MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISN
DGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQI
IIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVV
DAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALL
NVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVAT
QYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNF
FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL
RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDIN
NEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRG
RPH

Sequence of entity 7 (N, n), FASTA

>7NVM_7 Nanobody Nb18 (chains N, n)
QVQLVESGGGLVQAGGSLRLSCGASGTFFRINDMGWYRQASGKQRELVASITRGGTTDYA
DSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCKANRNWGREWDDYWGQGTQVTVSSH
HHHHHEPEA

Sequence of entity 8 (Q, q), FASTA

>7NVM_8 T-complex protein 1 subunit theta (chains Q, q)
MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHL
EKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLR
IGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLA
KLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIA
VYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADM
ALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQV
VVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELA
KQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGL
DIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKK
DWDDDQND

Sequence of entity 9 (Z, z), FASTA

>7NVM_9 T-complex protein 1 subunit zeta (chains Z, z)
MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG

Sequence of entity 10 (K), FASTA

>7NVM_10 Actin, cytoplasmic 2 (chains K)
MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF

Sequence of entity 11 (P), FASTA

>7NVM_11 Phosducin-like protein 3 (chains P)
MQDPNADTEWNDILRKKGILPPKESLKELEEEAEEEQRILQQSVVKTYEDMTLEELEDHE
DEFNEEDERAIEMYRRRRLAEWKATKLKNKFGEVLEISGKDYVQEVTKAGEGLWVILHLY
KQGIPLCALINQHLSGLARKFPDVKFIKAISTTCIPNYPDRNLPTIFVYLEGDIKAQFIG
PLVFGGMNLTRDELEWKLSESGAIMTDLEENPKKPIEDVLLSSVRRSVLMKRDSDSEGD

Ligands and cofactors

ID	Name	Formula	Copies
AF3	Aluminum fluoride	Al F3	16
MG	Magnesium ion	Mg	16
ADP	Adenosine-5'-diphosphate	C10 H15 N5 O10 P2	16

Primary citation

Snapshots of actin and tubulin folding inside the TRiC chaperonin. Kelly, J.J., Tranter, D., Pardon, E. et al. Nat Struct Mol Biol (2022) 29:420-429. DOI 10.1038/s41594-022-00755-1 · PubMed

Other PDB entries of the same protein (UniProt P17987 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7NVL 2.5 Å, Human TRiC complex in closed state with nanobody bound (Consensus Map)
8SH9 2.7 Å, CCT G beta 5 complex best PhLP1 class
9S72 2.71 Å, Human CCT in Closed Conformation
8SHE 2.8 Å, CCT-G beta 5 complex closed state 8
8SHG 2.8 Å, CCT G beta 5 complex closed state 9
8SHN 2.8 Å, CCT-G beta 5 complex closed state 6
7TTT 2.9 Å, The beta-tubulin folding intermediate III
8SG9 2.9 Å, CCT G beta 5 complex closed state 3
8SGC 2.9 Å, CCT G beta 5 complex closed state 2
8SGL 2.9 Å, CCT G beta 5 complex closed state 15
8SHD 2.9 Å, CCT G beta 5 complex closed state 10
8SHQ 2.9 Å, CCT G beta 5 complex closed state 12

Browse structure collections

About this viewer

MolViewer shows 7NVM directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.