7OGG: Nse5/6 complex

Nse5/6 complex. Determined by X-ray diffraction at 3.29 Å resolution. Released 7 Jul 2021.

Method
X-ray diffraction
Resolution
3.29 Å
Organisms
Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Saccharomyces cerevisiae A364A
Chains
2
Atoms
4,888
Mol. weight
105.13 kDa
Released
7 Jul 2021

Explore 7OGG in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7OGG contains 39 α-helices and 8 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain Q: 12 helices, 1 β-strand

ElementResiduesLengthSheet
β-strand11014
α-helix113-1219
α-helix132-14514
α-helix147-1526
α-helix159-1657
α-helix169-17911
α-helix185-19410
α-helix196-1983
α-helix199-2079
α-helix217-23014
α-helix235-2428
α-helix257-26913
α-helix277-29115
Chain R: 27 helices, 7 β-strands
ElementResiduesLengthSheet
α-helix4-74
β-strand1211
β-strand2211
α-helix26-4015
α-helix44-5310
α-helix63-653
α-helix66-7510
α-helix80-9011
α-helix100-11617
α-helix125-13915
α-helix191-1944
β-strand19712
β-strand20212
α-helix204-2085
α-helix213-22513
α-helix230-2345
α-helix235-2406
α-helix241-26121
α-helix271-2766
α-helix280-2878
α-helix302-3043
β-strand309-31023
β-strand317-31823
β-strand33614
α-helix340-36223
α-helix3661
α-helix380-39011
α-helix395-4028
α-helix407-4093
α-helix492-51625
α-helix559-56911
α-helix580-5867
α-helix589-5957
α-helix602-6054

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome…Rprotein607Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Saccharomyces cerevisiae A364AQ03718 (AlphaFold model)
DNA repair protein KRE29,DNA repair protein KRE29,DNA repair protein KRE29Qprotein308Saccharomyces cerevisiae A364AP40026 (AlphaFold model)
Sequence of entity 1 (R), FASTA
>7OGG_1 Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5 (chains R)
MDGALINSVLYVSPRNGAHYFVELTEKHLLAFEMLNSMCLLENYDHVLLFLECQFGKSHN
LAVIPFDIILVLFTLSTLSEYYKEPILRANDPYNTSRETLSRRALKLLQKYLAILKEFDS
EQYNLYDLELLRCQFFLAIDTLTPKKQKWGFDRFRRTKSESGVTYRQNASVDPELDQAKT
FKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFINMILWTLSNSLQESTPLFLSSHEIW
MPLLEILIDLFSCRQDYFIQHEVAQNVSKSLFVQRLSESPLAVFFESLNTRNFANRFSEY
VFLNCDYKLPSDNYATPVHPVYNGENTIVDTYIPTIKCSPLYKSQKSLALRRKLIGSCFK
LLLRVPDGHRLITPRIVADDVIQGISRTLASFNDILQFKKFFMTENLSQESYFIPLLAEG
TLSEILKDTQECVVILTLVENLSDGVSFCNEVIGLVKSKCFAFTEQCSQASYEEAVLNIE
KCDVCLLVLLRYLLHLIGTEAILDAKEQLEMLHAIEKNDSGRRQWAKALNLGNDPPLLYP
IVSQMFGVHDKSVIIEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX
Sequence of entity 2 (Q), FASTA
>7OGG_2 DNA repair protein KRE29,DNA repair protein KRE29,DNA repair protein KRE29 (chains Q)
GPAAMSGSIPEIYLDVVTKETISDKYKDWHFISKNCHYEQLMDLEMKDTAYSFLFGSSRS
QGKVPEFVHLKCPSITNLLVLFGVNQEKCNSLKINYEKKENSRYDNLCTIFPVNKMLKFL
MYFYSDDDNDDVREFFLKAFICLILDRKVFNAMESDHRLCFKVLELFNEAHFINSYFEIV
DKNDFFLHYRLLQIFPHLQSALLRRRFSEKQGRTETIQQNIIKEFNEFFDCKNYKNLLYF
ILTMYGSKFIPFGPKCQVTEYFKDCILDISNETTNDVEISILKGILNLFSKIRGXXXXXX
XXXXXXXX

Primary citation

Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding. Taschner, M., Basquin, J., Steigenberger, B. et al. EMBO J (2021) 40:e107807-e107807. DOI 10.15252/embj.2021107807 · PubMed

Other PDB entries of the same protein (UniProt Q03718 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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