Nse5-6 complex. Determined by electron microscopy at 3.2 Å resolution. Released 19 May 2021.
Explore 7LTO in 3D Show helices and sheets RCSB PDB PDBe
7LTO contains 34 α-helices and 8 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 26-40 | 15 | |
| α-helix | 44-52 | 9 | |
| α-helix | 63-65 | 3 | |
| α-helix | 66-75 | 10 | |
| α-helix | 84-90 | 7 | |
| α-helix | 100-115 | 16 | |
| α-helix | 127-139 | 13 | |
| β-strand | 198 | 1 | 1 |
| β-strand | 201 | 1 | 1 |
| α-helix | 216-219 | 4 | |
| α-helix | 230-235 | 6 | |
| α-helix | 236-240 | 5 | |
| α-helix | 241-254 | 14 | |
| α-helix | 256-259 | 4 | |
| β-strand | 283 | 1 | 2 |
| β-strand | 287 | 1 | 2 |
| α-helix | 294-301 | 8 | |
| α-helix | 318-320 | 3 | |
| β-strand | 336 | 1 | 3 |
| α-helix | 340-362 | 23 | |
| α-helix | 369-371 | 3 | |
| α-helix | 381-390 | 10 | |
| α-helix | 395-402 | 8 | |
| α-helix | 414-429 | 16 | |
| α-helix | 501-510 | 10 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 209-216 | 8 | |
| α-helix | 220-224 | 5 | |
| α-helix | 246-252 | 7 | |
| β-strand | 281 | 1 | 3 |
| α-helix | 284-291 | 8 | |
| α-helix | 301-316 | 16 | |
| α-helix | 318-321 | 4 | |
| α-helix | 330-335 | 6 | |
| α-helix | 340-345 | 6 | |
| α-helix | 355-365 | 11 | |
| α-helix | 371-377 | 7 | |
| α-helix | 389-396 | 8 | |
| α-helix | 405-415 | 11 | |
| β-strand | 416 | 1 | 4 |
| β-strand | 421 | 1 | 4 |
| α-helix | 433-440 | 8 | |
| α-helix | 449-461 | 13 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Non-structural maintenance of chromosome element 5 | A | protein | 567 | Saccharomyces cerevisiae | Q03718 (AlphaFold model) |
| Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera | B | protein | 586 | Saccharomyces cerevisiae | P40026 (AlphaFold model), Q12306 (AlphaFold model) |
>7LTO_1 Non-structural maintenance of chromosome element 5 (chains A) MADLNWISAGHMDGALINSVLYVSPRNGAHYFVELTEKHLLAFEMLNSMCLLENYDHVLL FLECQFGKSHNLAVIPFDIILVLFTLSTLSEYYKEPILRANDPYNTSRETLSRRALKLLQ KYLAILKEFDSEQYNLYDLELLRCQFFLAIDTLTPKKQKWGFDRFRRTKSESGVTYRQNA SVDPELDQAKTFKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFINMILWTLSNSLQES TPLFLSSHEIWMPLLEILIDLFSCRQDYFIQHEVAQNVSKSLFVQRLSESPLAVFFESLN TRNFANRFSEYVFLNCDYKLPSDNYATPVHPVYNGENTIVDTYIPTIKCSPLYKSQKSLA LRRKLIGSCFKLLLRVPDGHRLITPRIVADDVIQGISRTLASFNDILQFKKFFMTENLSQ ESYFIPLLAEGTLSEILKDTQECVVILTLVENLSDGVSFCNEVIGLVKSKCFAFTEQCSQ ASYEEAVLNIEKCDVCLLVLLRYLLHLIGTEAILDAKEQLEMLHAIEKNDSGRRQWAKAL NLGNDPPLLYPIVSQMFGVHDKSVIIE
>7LTO_2 Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera (chains B) MGSSHHHHHHSSGLVPRGSHMASMSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFF KIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIG GSMGSVNSSPNEEFETVPDSQISGFDSPLIPTSVGSYFRDDDDDEKVHPNFISDPENDSL NSDEEFSSLENSDLNLSGAKAESGDDFDPILKRTIISKRKAPSNNEDEEIVKTPRKLVNY VPLKIFNLGDSFDDTITTTVAKLQDLKKEILDSPRSNKSIVITSNTVAKSELQKSIKFSG SIPEIYLDVVTKETISDKYKDWHFISKNCHYEQLMDLEMKDTAYSFLFGSSRSQGKVPEF VHLKCPSITNLLVLFGVNQEKCNSLKINYEKKENSRYDNLCTIFPVNKMLKFLMYFYSDD DNDDVREFFLKAFICLILDRKVFNAMESDHRLCFKVLELFNEAHFINSYFEIVDKNDFFL HYRLLQIFPHLQSALLRRRFSEKQGRTETIQQNIIKEFNEFFDCKNYKNLLYFILTMYGS KFIPFGPKCQVTEYFKDCILDISNETTNDVEISILKGILNLFSKIR
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Yu, Y., Li, S., Ser, Z. et al. Proc Natl Acad Sci U S A (2021) 118. DOI 10.1073/pnas.2026844118 · PubMed
Other PDB entries of the same protein (UniProt Q03718 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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