7ON1: Cenp-A nucleosome
Cenp-A nucleosome in complex with Cenp-C. Determined by electron microscopy at 3.35 Å resolution. Released 7 Jul 2021.
- Method
- Electron microscopy
- Resolution
- 3.35 Å
- Organisms
- Saccharomyces cerevisiae, Escherichia coli
- Chains
- 12
- Atoms
- 11,150
- Mol. weight
- 342.54 kDa
- Released
- 7 Jul 2021
Explore 7ON1 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7ON1 contains 40 α-helices and 16 β-strands across 10 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 4 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 134-147 | 14 | |
| α-helix | 155-167 | 13 | |
| β-strand | 177-178 | 2 | 2 |
| α-helix | 180-207 | 28 | |
| β-strand | 212-213 | 2 | 1 |
| α-helix | 215-225 | 11 | |
Chain b: 4 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 26-29 | 4 | |
| α-helix | 32-42 | 11 | |
| β-strand | 46-47 | 2 | 1 |
| α-helix | 51-76 | 26 | |
| β-strand | 81-82 | 2 | 2 |
| α-helix | 84-93 | 10 | |
| β-strand | 97-99 | 3 | 3 |
Chain c: 5 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 19-23 | 5 | |
| α-helix | 30-37 | 8 | |
| β-strand | 44-45 | 2 | 4 |
| α-helix | 48-74 | 27 | |
| α-helix | 82-90 | 9 | |
| α-helix | 93-98 | 6 | |
| β-strand | 103-104 | 2 | 7 |
Chains C and D: 2 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 293-295 | 3 | |
| α-helix | 297-299 | 3 | |
Chain d: 5 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 35-38 | 4 | |
| α-helix | 42-52 | 11 | |
| α-helix | 60-87 | 28 | |
| β-strand | 92-93 | 2 | 4 |
| α-helix | 95-105 | 11 | |
| α-helix | 108-127 | 20 | |
Chain e: 4 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 134-147 | 14 | |
| α-helix | 155-168 | 14 | |
| β-strand | 177-178 | 2 | 5 |
| α-helix | 181-207 | 27 | |
| β-strand | 213 | 1 | 6 |
| α-helix | 215-225 | 11 | |
Chain f: 4 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 27-30 | 4 | |
| α-helix | 32-42 | 11 | |
| β-strand | 47 | 1 | 6 |
| α-helix | 51-76 | 26 | |
| β-strand | 81-82 | 2 | 5 |
| α-helix | 84-94 | 11 | |
| β-strand | 98-99 | 2 | 7 |
Chain g: 6 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 19-22 | 4 | |
| α-helix | 30-37 | 8 | |
| α-helix | 49-74 | 26 | |
| β-strand | 79-80 | 2 | 8 |
| α-helix | 82-90 | 9 | |
| α-helix | 93-98 | 6 | |
| β-strand | 102-104 | 3 | 3 |
| α-helix | 109-111 | 3 | |
1 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| BJ4_G0006610.mRNA.1.CDS.1 | C, D | protein | 549 | Saccharomyces cerevisiae | P35201 (AlphaFold model) |
| Histone H4 | b, f | protein | 105 | Saccharomyces cerevisiae | P02309 (AlphaFold model) |
| Histone H2B | d, h | protein | 133 | Saccharomyces cerevisiae | P02293 (AlphaFold model) |
| BJ4_G0007000.mRNA.1.CDS.1 | a, e | protein | 231 | Saccharomyces cerevisiae | P36012 (AlphaFold model) |
| Histone H2A | c, g | protein | 134 | Saccharomyces cerevisiae | P04911 |
| DNA (152-mer) | I | DNA | 147 | Escherichia coli | |
| DNA (123-mer) | J | DNA | 123 | Escherichia coli | |
Sequence of entity 1 (C, D), FASTA
>7ON1_1 BJ4_G0006610.mRNA.1.CDS.1 (chains C, D)
MDYMKLGLKSRKTGIDVKQDIPKDEYSMENIDDFFKDDETSLISMRRKSRRKSSLFLPST
LNGDTKNVLPPFLQSYKSQDDEVVQSPSGKGDGSRRSSLLSHQSNFLSPANDFEPIEEEP
EQEENDIRGNDFATPITQKLSKPTYKRKYSTRYSLDTSESPSVRLTPDRITNKNVYSDVP
DLVADEDDDDRVNTSLNTSDNALLEDELEDDGFIPESEEDGDYIESDSSLDSGSDSASDS
DGDNTYQEVEEEAEVNTNDNEDDYIRRQASDVVRTDSIIDRNGLRKSTRVKVAPLQYWRN
EKIVYKRKSNKPVLDIDKIVTYDESEDEEEILAAQRRKKQKKKPTPTRPYNYVPTGRPRG
RPKKDPNAKENLIPEDPNEDIIERIESGGIENGEWLKHGILEANVKISDTKEETKDEIIA
FAPNLSQTEQVKDTKDENFALEIMFDKHKEYFASGILKLPAISGQKKLSNSFRTYITFHV
IQGIVEVTVCKNKFLSVKGSTFQIPAFNEYAIANRGNDEAKMFFVQVTVSEDANDDNDKE
LDSTFDTFG
Sequence of entity 2 (b, f), FASTA
>7ON1_2 Histone H4 (chains b, f)
GAMSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAV
LKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG
Sequence of entity 3 (d, h), FASTA
>7ON1_3 Histone H2B (chains d, h)
GAMSAKAEKKPASKAPAEKKPAAKKTSTSTDGKKRSKARKETYSSYIYKVLKQTHPDTGI
SQKSMSILNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEG
TRAVTKYSSSTQA
Sequence of entity 4 (a, e), FASTA
>7ON1_4 BJ4_G0007000.mRNA.1.CDS.1 (chains a, e)
GAMSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQRTRATKNLFPRREER
RRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVRTHSYALDRYVRQKRRE
KQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRW
QSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI
Sequence of entity 5 (c, g), FASTA
>7ON1_5 Histone H2A (chains c, g)
GAMSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLE
YLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLL
PKKSAKATKASQEL
Sequence of entity 6 (I), FASTA
>7ON1_6 DNA (152-MER) (chains I)
ATCGAGAATCCCGGTGCCGAGGCCGCTCAATTGGTCGTAGACAGCTCTAGCACCGCTTAA
ACGCACGTACGCGCTGTCCCCCGCGTTTTAACCGCCAAGGGGATTACTCCCTAGTCTCCA
GGCACGTGTCAGATATATACATCCGAT
Sequence of entity 7 (J), FASTA
>7ON1_7 DNA (123-MER) (chains J)
TATCTGACACGTGCCTGGAGACTAGGGAGTAATCCCCTTGGCGGTTAAAACGCGGGGGAC
AGCGCGTACGTGCGTTTAAGCGGTGCTAGAGCTGTCTACGACCAATTGAGCGGCCTCGGC
ACC
Primary citation
Cenp-A nucleosome in complex with Cenp-C. Yan, K., Yang, J., Zhang, Z. et al. To be published.
Other PDB entries of the same protein (UniProt P35201 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 2VPV 2.7 Å, Dimerization Domain of Mif2p
- 6QLD 4.15 Å, Structure of inner kinetochore CCAN-Cenp-A complex
Browse structure collections
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