7QVP: 60S ribosomal protein L8
Human collided disome (di-ribosome) stalled on XBP1 mRNA. Determined by electron microscopy at 3.0 Å resolution. Released 12 Oct 2022.
- Method
- Electron microscopy
- Resolution
- 3.0 Å
- Organism
- Homo sapiens
- Chains
- 162
- Atoms
- 417,512
- Mol. weight
- 7725.76 kDa
- Released
- 12 Oct 2022
Explore 7QVP in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7QVP contains 926 α-helices and 1,038 β-strands across 148 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain La: 6 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-10 | 4 | |
| α-helix | 42-48 | 7 | |
| β-strand | 72-74 | 3 | 143 |
| α-helix | 75-78 | 4 | |
| α-helix | 79-81 | 3 | |
| α-helix | 84-92 | 9 | |
| β-strand | 97-98 | 2 | 281 |
| β-strand | 100-102 | 3 | 144 |
| β-strand | 110-112 | 3 | 143 |
| β-strand | 123-126 | 4 | 144 |
| β-strand | 128-129 | 2 | 143 |
| α-helix | 131-140 | 10 | |
| β-strand | 143-146 | 4 | 144 |
Chain LA: 7 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 4-5 | 2 | |
| α-helix | 30-32 | 3 | |
| α-helix | 34-38 | 5 | |
| β-strand | 41-50 | 10 | 153 |
| β-strand | 57-64 | 8 | 153 |
| β-strand | 71-77 | 7 | 153 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 154 |
| β-strand | 83 | 1 | 5 |
| β-strand | 86-90 | 5 | 153 |
| β-strand | 101-103 | 3 | 153 |
| β-strand | 111-113 | 3 | 155 |
| β-strand | 116 | 1 | 156 |
| β-strand | 126 | 1 | 156 |
| β-strand | 134-140 | 7 | 155 |
| β-strand | 145-149 | 5 | 155 |
| β-strand | 155-159 | 5 | 155 |
| β-strand | 163-165 | 3 | 153 |
| β-strand | 166 | 1 | 155 |
| β-strand | 169 | 1 | 154 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-192 | 11 | |
| β-strand | 224-225 | 2 | 157 |
| α-helix | 229-230 | 2 | |
| β-strand | 237-238 | 2 | 157 |
Chain Lb: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-18 | 7 | |
| α-helix | 37-48 | 12 | |
| α-helix | 54-75 | 22 | |
Chain LB: 13 helices, 21 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 20-22 | 3 | |
| α-helix | 32-35 | 4 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 166 |
| β-strand | 45-59 | 15 | 167 |
| β-strand | 63 | 1 | 168 |
| β-strand | 65 | 1 | 168 |
| β-strand | 71-80 | 10 | 167 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 166 |
| β-strand | 98-106 | 9 | 166 |
| α-helix | 112-118 | 7 | |
| α-helix | 131-138 | 8 | |
| α-helix | 140-156 | 17 | |
| β-strand | 159-165 | 7 | 166 |
| β-strand | 180-186 | 7 | 166 |
| α-helix | 190-199 | 10 | |
| β-strand | 203-205 | 3 | 166 |
| α-helix | 207-210 | 4 | |
| β-strand | 216-222 | 7 | 167 |
| β-strand | 228-229 | 2 | 169 |
| α-helix | 231-234 | 4 | |
| α-helix | 237-241 | 5 | |
| β-strand | 270-271 | 2 | 169 |
| β-strand | 276-289 | 14 | 167 |
| β-strand | 292 | 1 | 170 |
| β-strand | 298 | 1 | 170 |
| α-helix | 300-302 | 3 | |
| β-strand | 320 | 1 | 171 |
| β-strand | 324 | 1 | 171 |
| β-strand | 329-333 | 5 | 167 |
| β-strand | 343-349 | 7 | 167 |
| β-strand | 365-368 | 4 | 167 |
| α-helix | 382-389 | 8 | |
Chain Lc: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-21 | 12 | |
| β-strand | 26-29 | 4 | 172 |
| α-helix | 31-40 | 10 | |
| β-strand | 45-48 | 4 | 172 |
| α-helix | 54-67 | 14 | |
| β-strand | 70-73 | 4 | 172 |
| α-helix | 78-84 | 7 | |
| β-strand | 93-98 | 6 | 172 |
Chain LC: 19 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 7-11 | 5 | 180 |
| β-strand | 17-23 | 7 | 180 |
| α-helix | 24-25 | 2 | |
| α-helix | 34-47 | 14 | |
| β-strand | 64-65 | 2 | 181 |
| β-strand | 78-79 | 2 | 181 |
| β-strand | 89-90 | 2 | 181 |
| α-helix | 100-101 | 2 | |
| α-helix | 117-132 | 16 | |
| α-helix | 134-139 | 6 | |
| β-strand | 152-154 | 3 | 180 |
| α-helix | 156-158 | 3 | |
| α-helix | 164-174 | 11 | |
| α-helix | 177-185 | 9 | |
| β-strand | 188-189 | 2 | 182 |
| β-strand | 201-202 | 2 | 182 |
| β-strand | 208-211 | 4 | 180 |
| α-helix | 217-221 | 5 | |
| β-strand | 228-231 | 4 | 180 |
| α-helix | 237-240 | 4 | |
| β-strand | 250-253 | 4 | 180 |
| α-helix | 254-264 | 11 | |
| α-helix | 279-282 | 4 | |
| α-helix | 289-293 | 5 | |
| α-helix | 296-299 | 4 | |
| α-helix | 302-305 | 4 | |
| α-helix | 311-314 | 4 | |
| α-helix | 316-317 | 2 | |
| α-helix | 322-328 | 7 | |
| α-helix | 332-363 | 32 | |
Chain Ld: 4 helices, 9 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 21-23 | 3 | 183 |
| β-strand | 26-28 | 3 | 184 |
| α-helix | 29-33 | 5 | |
| α-helix | 38-40 | 3 | |
| α-helix | 41-56 | 16 | |
| β-strand | 62-63 | 2 | 183 |
| α-helix | 66-72 | 7 | |
| β-strand | 83-85 | 3 | 184 |
| β-strand | 86 | 1 | 185 |
| β-strand | 88-92 | 5 | 183 |
| β-strand | 102-105 | 4 | 183 |
| β-strand | 108 | 1 | 185 |
| β-strand | 121-122 | 2 | 183 |
Chain LD: 19 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-6 | 4 | |
| α-helix | 10-15 | 6 | |
| α-helix | 21-25 | 5 | |
| α-helix | 30-37 | 8 | |
| α-helix | 38-40 | 3 | |
| β-strand | 50-54 | 5 | 190 |
| β-strand | 61-68 | 8 | 190 |
| β-strand | 71-79 | 9 | 190 |
| α-helix | 83-86 | 4 | |
| α-helix | 95-111 | 17 | |
| α-helix | 139-142 | 4 | |
| β-strand | 143 | 1 | 191 |
| β-strand | 145-147 | 3 | 190 |
| α-helix | 158-169 | 12 | |
| β-strand | 172 | 1 | 191 |
| α-helix | 177-179 | 3 | |
| β-strand | 183-184 | 2 | 192 |
| β-strand | 189-190 | 2 | 192 |
| α-helix | 193-199 | 7 | |
| α-helix | 202-213 | 12 | |
| α-helix | 216-222 | 7 | |
| α-helix | 224-227 | 4 | |
| α-helix | 228-230 | 3 | |
| α-helix | 236-249 | 14 | |
| α-helix | 255-257 | 3 | |
| α-helix | 270-272 | 3 | |
| α-helix | 273-293 | 21 | |
139 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| mRNA | A4 | RNA | 14 | Homo sapiens | |
| mRNA | A5 | RNA | 11 | Homo sapiens | |
| tRNA P/P | B4, D5 | RNA | 76 | Homo sapiens | |
| tRNA P/E | B5 | RNA | 75 | Homo sapiens | |
| tNRA E/E | CC | RNA | 75 | Homo sapiens | |
| 5.8S ribosomal RNA | L1, L8 | RNA | 157 | Homo sapiens | |
| 28S ribosomal RNA | L5, L6 | RNA | 5227 | Homo sapiens | |
| 5S ribosomal RNA | L7, L9 | RNA | 121 | Homo sapiens | |
| 60S ribosomal protein L8 | LA, MA | protein | 257 | Homo sapiens | A0A8B8VPA8 (AlphaFold model) |
| 60S ribosomal protein L3 | LB, MB | protein | 403 | Homo sapiens | P39023 (AlphaFold model) |
| 60S ribosomal protein L4 | LC, MC | protein | 427 | Homo sapiens | P36578 (AlphaFold model) |
| 60S ribosomal protein L5 | LD, MD | protein | 297 | Homo sapiens | P46777 (AlphaFold model) |
73 more molecules are not listed.
Sequence of entity 1 (A4), FASTA
>7QVP_1 mRNA (chains A4)
UUUUUUUUUUUUUU
Sequence of entity 2 (A5), FASTA
>7QVP_2 mRNA (chains A5)
UUUUUUUUUUU
Sequence of entity 3 (B4, D5), FASTA
>7QVP_3 tRNA P/P (chains B4, D5)
GCCCGGAUAGCUCAGUCGGUAGAGCAGGGGAUUGAAAAUCCCCGUGUCCUUGGUUCGAUU
CCGAGUCCGGGCACCA
Sequence of entity 4 (B5), FASTA
>7QVP_4 tRNA P/E (chains B5)
AGCAGAGUGGCGCAGCGGAAGCGUGCUGGGCCCAUAACCCAGAGGUCGAUGGAUCGAAAC
CAUCCUCUGCUACCA
Sequence of entity 5 (CC), FASTA
>7QVP_5 tNRA E/E (chains CC)
UCCGAUAUAGCGUAACGGCUAUCACAUCACGCUUUCACCGUGGAGACCGGGGUUCGACUC
CCCGUAUCGGAGCCA
Sequence of entity 6 (L1, L8), FASTA
>7QVP_6 5.8S ribosomal RNA (chains L1, L8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCUU
Sequence of entity 7 (L5, L6), FASTA
>7QVP_7 28S ribosomal RNA (chains L5, L6)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCUUCGCGACCUCAGAUCAGACGUGGC
GACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAGAAGAAACUAACCAGGAUUCCCUC
AGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGAAUCCCCGCCCCGCGGCGGGGCGC
GGGACAUGUGGCGUACGGAAGACCCGCUCCCCGGCGCCGCUCGUGGGGGGCCCAAGUCCU
UCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCGGUAGCGGCCCCCGGCGCGCCGGG
CCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCAGCCCAAAGCGGGUGGUAAACUCC
AUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAACAAGUACCGUAAGGGAAAGUUGA
AAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAACCGUUAAGAGGUAAACGGGUGGG
GUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGCGGGUCCGGCCGUGUCGGCGGCCC
GGCGGAUCUUUCCCGCCCCCCGUUCCUCCCGACCCCUCCACCCGCCCUCCCUUCCCCCGC
CGCCCCUCCUCCUCCUCCCCGGAGGGGGCGGGCUCCGGCGGGUGCGGGGGUGGGCGGGCG
GGGCCGGGGGUGGGGUCGGCGGGGGACCGUCCCCCGACCGGCGACCGGCCGCCGCCGGGC
GCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCGGGACGGCUGGGAAGGCCCGGCGG
GGAAGGUGGCUCGGGGGGCCCCGUCCGUCCGUCCGUCCGUCCUCCUCCUCCCCCGUCUCC
GCCCCCCGGCCCCGCGUCCUCCCUCGGGAGGGCGCGCGGGUCGGGGCGGCGGCGGCGGCG
GCGGUGGCGGCGGCGGCGGCGGCGGCGGGACCGAAACCCCCCCCGAGUGUUACAGCCCCC
CCGGCAGCAGCACUCGCCGAAUCCCGGGGCCGAGGGAGCGAGACCCGUCGCCGCGCUCUC
CCCCCUCCCGGCGCCCACCCCCGCGGGGAAUCCCCCGCGAGGGGGGUCUCCCCCGCGGGG
GCGCGCCGGCGUCUCCUCGUGGGGGGGCCGGGCCACCCCUCCCACGGCGCGACCGCUCUC
CCACCCCUCCUCCCCGCGCCCCCGCCCCGGCGACGGGGGGGGUGCCGCGCGCGGGUCGGG
GGGCGGGGCGGACUGUCCCCAGUGCGCCCCGGGCGGGUCGCGCCGUCGGGCCCGGGGGAG
GUUCUCUCGGGGCCACGCGCGCGUCCCCCGAAGAGGGGGACGGCGGAGCGAGCGCACGGG
GUCGGCGGCGACGUCGGCUACCCACCCGACCCGUCUUGAAACACGGACCAAGGAGUCUAA
CACGUGCGCGAGUCGGGGGCUCGCACGAAAGCCGCCGUGGCGCAAUGAAGGUGAAGGCCG
GCGCGCUCGCCGGCCGAGGUGGGAUCCCGAGGCCUCUCCAGUCCGCCGAGGGCGCACCAC
CGGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGCACGAGCGCACGUGUUAGGACCCGA
AAGAUGGUGAACUAUGCCUGGGCAGGGCGAAGCCAGAGGAAACUCUGGUGGAGGUCCGUA
GCGGUCCUGACGUGCAAAUCGGUCGUCCGACCUGGGUAUAGGGGCGAAAGACUAAUCGAA
CCAUCUAGUAGCUGGUUCCCUCCGAAGUUUCCCUCAGGAUAGCUGGCGCUCUCGCAGACC
CGACGCACCCCCGCCACGCAGUUUUAUCCGGUAAAGCGAAUGAUUAGAGGUCUUGGGGCC
GAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUAAGAAGCCCGGCUCGCUGGCGUG
GAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUUUUGGUAAGCAGAACUGGCGCUG
CGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCCGACGCUCAUCAGACCCCAGAAA
AGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGAG
UGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAAAAUGGAUGGCGCUGGAGCGUCG
GGCCCAUACCCGGCCGUCGCCGGCAGUCGAGAGUGGACGGGAGCGGCGGGGGCGGCGCGC
GCGCGCGCGCGUGUGGUGUGCGUCGGAGGGCGGCGGCGGCGGCGGCGGCGGGGGUGUGGG
GUCCUUCCCCCGCCCCCCCCCCCACGCCUCCUCCCCUCCUCCCGCCCACGCCCCGCUCCC
CGCCCCCGGAGCCCCGCGGACGCUACGCCGCGACGAGUAGGAGGGCCGCUGCGGUGAGCC
UUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCCGCAGGUGCAGAUCUUGGUGGUAGUA
GCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGUGGAGAAGGGUUCCAUGUGAACAGCA
GUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGCGAGCGCCGUUCCGAAGGGACGGGCG
AUGGCCUCCGUUGCCCUCGGCCGAUCGAAAGGGAGUCGGGUUCAGAUCCCCGAAUCCGGA
GUGGCGGAGAUGGGCGCCGCGAGGCGUCCAGUGCGGUAACGCGACCGAUCCCGGAGAAGC
CGGCGGGAGCCCCGGGGAGAGUUCUCUUUUCUUUGUGAAGGGCAGGGCGCCCUGGAAUGG
GUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAGCGUCGCGGUUCCGGCGGCGUCCGGU
GAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAGGGUGUAAAUCUCGCGCCGGGCCGUA
CCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCCUCUGGCAUGUUGGAACAAUGUAGGU
AAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGCUGGG
UCGGUCGGGCUGGGGCGCGAAGCGGGGCUGGGCGCGCGCCGCGGCUGGACGAGGCGCCGC
CGCCCCCCCCACGCCCGGGGCACCCCCCUCGCGGCCCUCCCCCGCCCCACCCCGCGCGCG
CCGCUCGCUCCCUCCCCGCCCCGCGCCCUCUCUCUCUCUCUCUCCCCCGCUCCCCGUCCU
CCCCCCUCCCCGGGGGAGCGCCGCGUGGGGGCGGCGGCGGGGGGAGAAGGGUCGGGGCGG
CAGGGGCCGGCGGCGGCCCGCCGCGGGGCCCCGGCGGCGGGGGCACGGUCCCCCGCGAGG
GGGGCCCGGGCACCCGGGGGGCCGGCGGCGGCGGCGACUCUGGACGCGAGCCGGGCCCUU
CCCGUGGAUCGCCCCAGCUGCGGCGGGCGUCGCGGCCGCCCCCGGGGAGCCCGGCGGGCG
CCGGCGCGCCCCCCCCCCCACCCCACGUCUCGUCGCGCGCGCGUCCGCUGGGGGCGGGGA
GCGGUCGGGCGGCGGCGGUCGGCGGGCGGCGGGGCGGGGCGGUUCGUCCCCCCGCCCUAC
CCCCCCGGCCCCGUCCGCCCCCCGUUCCCCCCUCCUCCUCGGCGCGCGGCGGCGGCGGCG
GCAGGCGGCGGAGGGGCCGCGGGCCGGUCCCCCCCGCCGGGUCCGCCCCCGGGGCCGCGG
UUCCGCGCGGCGCCUCGCCUCGGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACC
AGGGGAAUCCGACUGUUUAAUUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGAC
GCGAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGG
GUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUA
GUGACGCGCAUGAAUGGAUGAACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAAC
CACAGCCAAGGGAACGGGCUUGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGA
CUCUAGUCUGGCACGGUGAAGAGACAUGAGAGGUGUAGAAUAAGUGGGAGGCCCCCGGCG
CCCCCCCGGUGUCCCCGCGAGGGGCCCGGGGCGGGGUCCGCCGGCCCUGCGGGCCGCCGG
UGAAAUACCACUACUCUGAUCGUUUUUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCCC
GAGGGGCUCUCGCUUCUGGCGCCAAGCGCCCGGCCGCGCGCCGGCCGGGCGCGACCCGCU
CCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCGGUACACCUGUCAAACGGUAACGC
AGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCUCCCGUGGAGCAGAAGGGCAAAAG
CUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCGUGAAAGCGGGGCCUCACGAUCCU
UCUGACCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAAAGUUACCACAGGGAUAACUGGCU
UGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUGAUCCUUCGAUGUCGGCUCUUCCU
AUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGUUCACCCACUAAUAGGGAACGUGA
GCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAUGUGUUGUUGCC
AUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUUCAGACAUUUGGUGUAUGUGCUUG
GCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGGAUUAUGACUGAACGCCUCUAAGU
CAGAAUCCCGCCCAGGCGGAACGAUACGGCAGCGCCGCGGAGCCUCGGUUGGCCUCGGAU
AGCCGGUCCCCCGCCUGUCCCCGCCGGCGGGCCGCCCCCCCCCUCCACGCGCCCCGCGCG
CGCGGGAGGGCGCGUGCCCC
Sequence of entity 8 (L7, L9), FASTA
>7QVP_8 5S ribosomal RNA (chains L7, L9)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
U
Sequence of entity 9 (LA, MA), FASTA
>7QVP_9 60S ribosomal protein L8 (chains LA, MA)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAA
RRTGRLRGTKTVQEKEN
Sequence of entity 10 (LB, MB), FASTA
>7QVP_10 60S ribosomal protein L3 (chains LB, MB)
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREV
DRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYK
NWHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHL
MEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKL
PRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIK
NNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRAL
EKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA
Sequence of entity 11 (LC, MC), FASTA
>7QVP_11 60S ribosomal protein L4 (chains LC, MC)
MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGH
QTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQK
RYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDI
KKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKL
APGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQR
ALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVDKAAAAAAA
LQAKSDEKAAVAGKKPVVGKKGKKAAVGVKKQKKPLVGKKAAATKKPAPEKKPAEKKPTT
EEKKPAA
Sequence of entity 12 (LD, MD), FASTA
>7QVP_12 60S ribosomal protein L5 (chains LD, MD)
MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDI
ICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYE
GQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRF
PGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMMEEMY
KKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES
Primary citation
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. Narita, M., Denk, T., Matsuo, Y. et al. Nat Commun (2022) 13:6411-6411. DOI 10.1038/s41467-022-34097-9 · PubMed
Other PDB entries of the same protein (UniProt A0A8B8VPA8 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7ZJW 2.8 Å, Rabbit 80S ribosome as it decodes the Sec-UGA codon
- 7QGG 2.86 Å, Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state
- 7ZJX 3.1 Å, Rabbit 80S ribosome programmed with SECIS and SBP2
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