P36578: Large ribosomal subunit protein uL4 (RPL4)

Large ribosomal subunit protein uL4 (RPL4) is a 427-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P36578.

Gene
RPL4
Organism
Homo sapiens
Length
427 residues
Mean pLDDT
87.1
Model
AF-P36578-F1 v6
Model created
1 Aug 2025
PDB structures
172

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Model confidence (pLDDT)

The mean pLDDT of this model is 87.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate82%
70 to 90Confident: backbone generally right2%
50 to 70Low: treat with caution2%
Below 50Very low: often disordered regions14%

What pLDDT means and how to read it

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Subunit structure

Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). May bind IPO9 with low affinity (PubMed:11823430). Interacts with RBM3 (By similarity)

Subcellular location

Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8A3DEM1.67 ÅF=1-427
8GLPEM1.67 ÅLC=1-427
8QYXEM1.78 ÅF2=1-427
8QOIEM1.9 ÅLC=1-368
9O3WEM1.9 ÅLC=1-427
8YOOEM2.0 ÅLC=1-427
9C3HEM2.0 ÅLC=1-427
9I2DEM2.19 ÅLC=1-427
9PBEEM2.19 ÅLC=1-368
7OW7EM2.2 ÅF=1-427
8QFDEM2.2 ÅC=1-427
8YOPEM2.2 ÅLC=1-427
9GULEM2.2 ÅLC=1-427
9O3YEM2.2 ÅLC=1-427
8JDKEM2.26 ÅI=1-427
8G5YEM2.29 ÅLC=1-427
9S3DEM2.32 ÅLC=1-427
9RPVEM2.35 ÅLC/MC=1-427
9S3BEM2.38 ÅLC=1-427
8K2CEM2.4 ÅLC=1-427

Showing 20 of 172 experimental structures (best resolution first).

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